Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 94309736

GI number: 94309736

Start: 867319

End: 868035

Strand: Direct

Name: fabG [H]

Synonym: Rmet_0791

Alternate gene names: 94309736

Gene position: 867319-868035 (Clockwise)

Preceding gene: 335055504

Following gene: 94309737

Centisome position: 22.08

GC content: 68.34

Gene sequence:

>717_bases
GTGTGCCGATGCGCTCGCGGCGGAAGGCGTGGATGTGGTGATCGTGGCGCCGAGGCGCTGGAGAAGGCTGCAGCCGATCT
GCGCGCCCGTCACGGCCGCCGCGTGCTGGCGGTGGCTACCGACATTACCACGGCGGAAGGCCGCAAGCTTGCCCTCGACG
CAGCCACGAAGCTGGGCGATCTCGACATCCTGGTCAACAATGCCGGCGGCCCGCCTCCGGGCAACTTCCGCGATTGGGGC
CGCGACGAATGGCTCAAGGCGCTCGACGCCAACATGCTGACCCCGATCGAGCTGATCAAGGCCACGGTCGATGGCATGAT
CGCGCGCCGCTGGGGCCGCATCATCAACATCACGAGTGGCGCGGTGAAGGCGCCGATCGACGTGCTGGGCCTGTCCAACG
GCGCCCGCTCGGGGCTGACCGGTTTCGTCGCCGGCCTGGCGCGCGAAGTGGCGCAGCATGGCGTGACCGTCAACAACCTG
CTGCCCGGACCGTTCAACACCGATCGTCTCTACAAGACGATGGAAGGCGGCGCGCAGAAGGCCGGCATCAGCGTCGATGA
AATGGCGCAGCGCCGCGCGGCGTCCAACCCGACGCGCCGCTTTGGCGACCCGGCTGAGTTCGGCGCTACCTGCGCGTTCC
TGTGCAGCCGCCAGGCCGCATACATGACCGGCCAGAATGTGCTGCTCGACGGCGGTGCGTATCCGGGGACGTTCTGA

Upstream 100 bases:

>100_bases
TTCGAGAAGAATCAACCAAGGAAGGAGAGCAAGAAATGGATCTCGGACTGCGCGGTAAGCATGCGCTGGTGTGTGGCGCC
AGCAAGGGGCTCGGGTTTGC

Downstream 100 bases:

>100_bases
CATGCGCAGCAAGCCACGCATCGCGCTGATCGCGCACGATCGCAAGAAGGATGACATCGTCGCGTTCGCGGGTCGCCATC
GGGACTTCCTGGCTCAATGC

Product: dehydrogenase with different specificities (short-chain alcohol dehydrogenases)

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MCRCARGGRRGCGDRGAEALEKAAADLRARHGRRVLAVATDITTAEGRKLALDAATKLGDLDILVNNAGGPPPGNFRDWG
RDEWLKALDANMLTPIELIKATVDGMIARRWGRIINITSGAVKAPIDVLGLSNGARSGLTGFVAGLAREVAQHGVTVNNL
LPGPFNTDRLYKTMEGGAQKAGISVDEMAQRRAASNPTRRFGDPAEFGATCAFLCSRQAAYMTGQNVLLDGGAYPGTF

Sequences:

>Translated_238_residues
MCRCARGGRRGCGDRGAEALEKAAADLRARHGRRVLAVATDITTAEGRKLALDAATKLGDLDILVNNAGGPPPGNFRDWG
RDEWLKALDANMLTPIELIKATVDGMIARRWGRIINITSGAVKAPIDVLGLSNGARSGLTGFVAGLAREVAQHGVTVNNL
LPGPFNTDRLYKTMEGGAQKAGISVDEMAQRRAASNPTRRFGDPAEFGATCAFLCSRQAAYMTGQNVLLDGGAYPGTF
>Mature_238_residues
MCRCARGGRRGCGDRGAEALEKAAADLRARHGRRVLAVATDITTAEGRKLALDAATKLGDLDILVNNAGGPPPGNFRDWG
RDEWLKALDANMLTPIELIKATVDGMIARRWGRIINITSGAVKAPIDVLGLSNGARSGLTGFVAGLAREVAQHGVTVNNL
LPGPFNTDRLYKTMEGGAQKAGISVDEMAQRRAASNPTRRFGDPAEFGATCAFLCSRQAAYMTGQNVLLDGGAYPGTF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=228, Percent_Identity=30.2631578947368, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI5031737, Length=232, Percent_Identity=28.0172413793103, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI66933014, Length=224, Percent_Identity=26.7857142857143, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI19923817, Length=224, Percent_Identity=27.2321428571429, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI40254992, Length=236, Percent_Identity=26.6949152542373, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1787335, Length=233, Percent_Identity=33.4763948497854, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI87082100, Length=220, Percent_Identity=35.4545454545455, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788459, Length=204, Percent_Identity=30.8823529411765, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=29.4354838709677, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790717, Length=233, Percent_Identity=26.1802575107296, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1789208, Length=208, Percent_Identity=27.4038461538462, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1787905, Length=220, Percent_Identity=28.1818181818182, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI2367365, Length=194, Percent_Identity=29.3814432989691, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=186, Percent_Identity=31.1827956989247, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560220, Length=239, Percent_Identity=28.8702928870293, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=240, Percent_Identity=30, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=208, Percent_Identity=27.8846153846154, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=238, Percent_Identity=27.3109243697479, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=199, Percent_Identity=28.1407035175879, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=230, Percent_Identity=26.9565217391304, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=213, Percent_Identity=26.7605633802817, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=230, Percent_Identity=28.2608695652174, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=216, Percent_Identity=28.7037037037037, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=240, Percent_Identity=25.8333333333333, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=234, Percent_Identity=26.9230769230769, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=206, Percent_Identity=27.6699029126214, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=199, Percent_Identity=26.1306532663317, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=207, Percent_Identity=28.0193236714976, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI23397609, Length=225, Percent_Identity=31.1111111111111, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21355319, Length=223, Percent_Identity=26.9058295964126, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28571526, Length=222, Percent_Identity=28.3783783783784, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21357041, Length=230, Percent_Identity=27.3913043478261, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24644339, Length=222, Percent_Identity=25.6756756756757, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25153; Mature: 25153

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRCARGGRRGCGDRGAEALEKAAADLRARHGRRVLAVATDITTAEGRKLALDAATKLGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEHHHHHCCCC
LDILVNNAGGPPPGNFRDWGRDEWLKALDANMLTPIELIKATVDGMIARRWGRIINITSG
EEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCC
AVKAPIDVLGLSNGARSGLTGFVAGLAREVAQHGVTVNNLLPGPFNTDRLYKTMEGGAQK
CHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHCCHHH
AGISVDEMAQRRAASNPTRRFGDPAEFGATCAFLCSRQAAYMTGQNVLLDGGAYPGTF
CCCCHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHCHHHHCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MCRCARGGRRGCGDRGAEALEKAAADLRARHGRRVLAVATDITTAEGRKLALDAATKLGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEHHHHHCCCC
LDILVNNAGGPPPGNFRDWGRDEWLKALDANMLTPIELIKATVDGMIARRWGRIINITSG
EEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCC
AVKAPIDVLGLSNGARSGLTGFVAGLAREVAQHGVTVNNLLPGPFNTDRLYKTMEGGAQK
CHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHCCHHH
AGISVDEMAQRRAASNPTRRFGDPAEFGATCAFLCSRQAAYMTGQNVLLDGGAYPGTF
CCCCHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHCHHHHCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]