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The map label for this gene is nudL [H]

Identifier: 94309697

GI number: 94309697

Start: 827862

End: 828596

Strand: Direct

Name: nudL [H]

Synonym: Rmet_0752

Alternate gene names: 94309697

Gene position: 827862-828596 (Clockwise)

Preceding gene: 94309696

Following gene: 94309699

Centisome position: 21.08

GC content: 61.5

Gene sequence:

>735_bases
ATGCGTTCTTGCTGCCATGCAACATTACGCGCTTCTGTCATACTTGAAAGCGCTATGCGTCCAACATTCGATCCTGAAAC
GCTACCGATCATCGAGACCGATAGCCGCCACGCCCCCCTCTCCACGCCGCGCATGAGACCGGATTTCATCCGGCATCGTC
TGCTTGCGCCACCGGCGTGGGAACCCGAACTGACCGATGAATCCCGTGTGTACGACCGGACCCGCGGCTTGCGTGAGGCG
GCGGTACTGGTGCCCCTGGTTGAGCGTTCGGATGGTCTGACGGTGCTGCTTACTCAGCGCAATGCGAATCTGAATGCCCA
TGCCGGGCAGATCAGTTTTCCGGGAGGCGGGCAGGAAACCTACGATGCCAATCGCATCGCCACGGCGTTGCGCGAAACCG
AGGAAGAGATCGGGCTGACCCGTAATTACGTCGAAGTGCTGGGATCGCTACCGGACTACATCACCGGTACCGGCTATCAC
GTCAGCCCCGTTGTCGGACTGGTGCATTCAGGGTTCACGCTCCGTGCCGATGAACGCGAAGTGGCCGATATCTTTGAGGT
GCCGCTGGCATTCCTGATGGACCCCGCGCGGCATGAGCGCCGGTTATTCCGCTGGGAAGGCGGCGAGCGCATGTTCTACG
CCATGCCTTATCCGCGCGAAGGCGGCGGTCAGCGCTTTATCTGGGGCGCGACGGCGGGCATGCTGCGCAATCTCTACCAC
CTGCTCGCGGCCTGA

Upstream 100 bases:

>100_bases
CGGAATAAGCTTTCCCTGTCAGGCGCCGGGTAACTGGCGCTGTGCCGGATTGCGAAGGACACCCTCGGGTGTCCTTTTTG
TTTGGCGGCGGCGCAACGCA

Downstream 100 bases:

>100_bases
GCCGCGCCGCCGCCCGCGACGCCGGTCTTCGTCAGGCTGCGGCCTGAGTAGCGGTGTCGACGCAGTGGGGGCAGCTCTTG
CCCACCACGTACTTCGGGTG

Product: putative NTP pyrophosphohydrolase (oxidative damage repair enzyme); MutT/nudix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MRSCCHATLRASVILESAMRPTFDPETLPIIETDSRHAPLSTPRMRPDFIRHRLLAPPAWEPELTDESRVYDRTRGLREA
AVLVPLVERSDGLTVLLTQRNANLNAHAGQISFPGGGQETYDANRIATALRETEEEIGLTRNYVEVLGSLPDYITGTGYH
VSPVVGLVHSGFTLRADEREVADIFEVPLAFLMDPARHERRLFRWEGGERMFYAMPYPREGGGQRFIWGATAGMLRNLYH
LLAA

Sequences:

>Translated_244_residues
MRSCCHATLRASVILESAMRPTFDPETLPIIETDSRHAPLSTPRMRPDFIRHRLLAPPAWEPELTDESRVYDRTRGLREA
AVLVPLVERSDGLTVLLTQRNANLNAHAGQISFPGGGQETYDANRIATALRETEEEIGLTRNYVEVLGSLPDYITGTGYH
VSPVVGLVHSGFTLRADEREVADIFEVPLAFLMDPARHERRLFRWEGGERMFYAMPYPREGGGQRFIWGATAGMLRNLYH
LLAA
>Mature_244_residues
MRSCCHATLRASVILESAMRPTFDPETLPIIETDSRHAPLSTPRMRPDFIRHRLLAPPAWEPELTDESRVYDRTRGLREA
AVLVPLVERSDGLTVLLTQRNANLNAHAGQISFPGGGQETYDANRIATALRETEEEIGLTRNYVEVLGSLPDYITGTGYH
VSPVVGLVHSGFTLRADEREVADIFEVPLAFLMDPARHERRLFRWEGGERMFYAMPYPREGGGQRFIWGATAGMLRNLYH
LLAA

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=155, Percent_Identity=34.8387096774194, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1788115, Length=162, Percent_Identity=43.2098765432099, Blast_Score=101, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17536993, Length=180, Percent_Identity=32.2222222222222, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17510677, Length=180, Percent_Identity=31.6666666666667, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI18859683, Length=172, Percent_Identity=34.3023255813954, Blast_Score=85, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 27442; Mature: 27442

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSCCHATLRASVILESAMRPTFDPETLPIIETDSRHAPLSTPRMRPDFIRHRLLAPPAW
CCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCC
EPELTDESRVYDRTRGLREAAVLVPLVERSDGLTVLLTQRNANLNAHAGQISFPGGGQET
CCCCCCHHHHHHHHCCHHHHHHHHHHEECCCCCEEEEEECCCCCCCCCCEEECCCCCCCC
YDANRIATALRETEEEIGLTRNYVEVLGSLPDYITGTGYHVSPVVGLVHSGFTLRADERE
CHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHCCEEEECCCHH
VADIFEVPLAFLMDPARHERRLFRWEGGERMFYAMPYPREGGGQRFIWGATAGMLRNLYH
HHHHHHHHHHHHCCHHHHHHHEEEECCCCEEEEECCCCCCCCCCEEEEHHHHHHHHHHHH
LLAA
HHCC
>Mature Secondary Structure
MRSCCHATLRASVILESAMRPTFDPETLPIIETDSRHAPLSTPRMRPDFIRHRLLAPPAW
CCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCC
EPELTDESRVYDRTRGLREAAVLVPLVERSDGLTVLLTQRNANLNAHAGQISFPGGGQET
CCCCCCHHHHHHHHCCHHHHHHHHHHEECCCCCEEEEEECCCCCCCCCCEEECCCCCCCC
YDANRIATALRETEEEIGLTRNYVEVLGSLPDYITGTGYHVSPVVGLVHSGFTLRADERE
CHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHCCEEEECCCHH
VADIFEVPLAFLMDPARHERRLFRWEGGERMFYAMPYPREGGGQRFIWGATAGMLRNLYH
HHHHHHHHHHHHCCHHHHHHHEEEECCCCEEEEECCCCCCCCCCEEEEHHHHHHHHHHHH
LLAA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA