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The map label for this gene is pilH [H]

Identifier: 94309615

GI number: 94309615

Start: 736776

End: 737144

Strand: Direct

Name: pilH [H]

Synonym: Rmet_0670

Alternate gene names: 94309615

Gene position: 736776-737144 (Clockwise)

Preceding gene: 94309614

Following gene: 94309616

Centisome position: 18.76

GC content: 62.6

Gene sequence:

>369_bases
ATGACCATCAGCAAAATCCTTATCGTCGACGATTCGCCCACCGAAGCCCTGTTCATGTCCGACCTGCTCGGCAAGAAGGG
CTTCAAGGTTTCCGTGGCCGGCAACAGCGACCAGGCCATGGCCCGGCTCGAGGCGGACGCTTTCGACCTGATCCTGATGG
ACGTGGTGATGCCGGGCCAGAACGGCTACCAGGCCACGCGCGCGATCAAGCGCGACGACCGCTTCAAGGACATCCCAGTG
ATCATGTGCACCAGCAAGGGCCTGGAAACCGACCGGATCTGGGGCATGCGCCAGGGCGCGTCGGACTACGTCGTCAAGCC
GGTGGACAGCGAAGAACTGCTGTCGAAGATCGCCGCGCTGGCGAACTGA

Upstream 100 bases:

>100_bases
CTGCAGGCCGTTCAGTCCTGCCTGACGGGTTGCGTGGCCGACGAGGGTGCGGCCGTGGCGGCCTGAGAACCGACCGCCAG
AAGCATCCAGGAACAAGACA

Downstream 100 bases:

>100_bases
GCCAGCCAGCCCATCAGCAAGCGGGCAGCGCGCTCCGGCACCACTGCCCCAAGGTTTCACCAACTGGTATCCCCATCATG
AACGCGCCGCGCCAAGACCT

Product: type IV pilus response regulator PilH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MTISKILIVDDSPTEALFMSDLLGKKGFKVSVAGNSDQAMARLEADAFDLILMDVVMPGQNGYQATRAIKRDDRFKDIPV
IMCTSKGLETDRIWGMRQGASDYVVKPVDSEELLSKIAALAN

Sequences:

>Translated_122_residues
MTISKILIVDDSPTEALFMSDLLGKKGFKVSVAGNSDQAMARLEADAFDLILMDVVMPGQNGYQATRAIKRDDRFKDIPV
IMCTSKGLETDRIWGMRQGASDYVVKPVDSEELLSKIAALAN
>Mature_121_residues
TISKILIVDDSPTEALFMSDLLGKKGFKVSVAGNSDQAMARLEADAFDLILMDVVMPGQNGYQATRAIKRDDRFKDIPVI
MCTSKGLETDRIWGMRQGASDYVVKPVDSEELLSKIAALAN

Specific function: May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction) [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=116, Percent_Identity=37.0689655172414, Blast_Score=86, Evalue=5e-19,
Organism=Escherichia coli, GI1789809, Length=116, Percent_Identity=36.2068965517241, Blast_Score=84, Evalue=3e-18,
Organism=Escherichia coli, GI1788394, Length=116, Percent_Identity=33.6206896551724, Blast_Score=82, Evalue=1e-17,
Organism=Escherichia coli, GI2367329, Length=118, Percent_Identity=39.8305084745763, Blast_Score=71, Evalue=3e-14,
Organism=Escherichia coli, GI1787229, Length=117, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=4e-14,
Organism=Escherichia coli, GI1786784, Length=116, Percent_Identity=31.0344827586207, Blast_Score=68, Evalue=2e-13,
Organism=Escherichia coli, GI87082012, Length=115, Percent_Identity=28.695652173913, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1788191, Length=117, Percent_Identity=33.3333333333333, Blast_Score=61, Evalue=3e-11,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=32.4324324324324, Blast_Score=60, Evalue=4e-11,
Organism=Escherichia coli, GI1789149, Length=108, Percent_Identity=31.4814814814815, Blast_Score=59, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=110, Percent_Identity=31.8181818181818, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 13371; Mature: 13239

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISKILIVDDSPTEALFMSDLLGKKGFKVSVAGNSDQAMARLEADAFDLILMDVVMPGQ
CCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCHHHHHEEEEECCCC
NGYQATRAIKRDDRFKDIPVIMCTSKGLETDRIWGMRQGASDYVVKPVDSEELLSKIAAL
CCHHHHHHHHCCCCCCCCCEEEECCCCCCCHHCCCCCCCCCCCEECCCCHHHHHHHHHHH
AN
CC
>Mature Secondary Structure 
TISKILIVDDSPTEALFMSDLLGKKGFKVSVAGNSDQAMARLEADAFDLILMDVVMPGQ
CCEEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCHHHHHEEEEECCCC
NGYQATRAIKRDDRFKDIPVIMCTSKGLETDRIWGMRQGASDYVVKPVDSEELLSKIAAL
CCHHHHHHHHCCCCCCCCCEEEECCCCCCCHHCCCCCCCCCCCEECCCCHHHHHHHHHHH
AN
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7908398; 10984043 [H]