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The map label for this gene is degU [H]

Identifier: 94309557

GI number: 94309557

Start: 666464

End: 667159

Strand: Direct

Name: degU [H]

Synonym: Rmet_0612

Alternate gene names: 94309557

Gene position: 666464-667159 (Clockwise)

Preceding gene: 94309556

Following gene: 94309558

Centisome position: 16.97

GC content: 62.64

Gene sequence:

>696_bases
TTGCCCGACACGGCTGAATCGGTGTTGCCAGCGCCCCTGCTGGTCGTTGAAGACGAGCCGCCGATGCAGTCCAGGCTACG
CACGATCCTGGCCGCACTGGGTTATGGCGACGACGCCATATGGTTTGCCGGCAGTCTCGAGGCTGCCAACACGCTGCTGG
CCACGCAGCCGTTCGCCATGGCGCTGGTTGATGTGGGGCTGCCCGACGGCAACGGCATCGACCTCATTCGGGTGATGCAC
GAGCAAGACCCGGCCCTGCCAATTTTGGTAATCTCCACGTGGAATACGGAACGGGTCATCGTAAGCGCGCTGCAGGCCGG
TGCCACCGGCTACCTGCTCAAGGAGCGCGACGACGTCGAGATCATTCTGTCGATTCGCAGCGCGCTGCGGGGTGGCGCAC
CGATCGACCCCTTCGTGGCCAGGCGCATTCTCGATCTGGCTGGAAAGATGGCGCCGCTGGCTGGCGGCGCGGAAGTCCAG
GCCGGGCCGACGGTCGGTGCGCCGCCACTGAGCGCGCGAGAAATAGAAATCCTCTCGCTGGTAAGCAAGGGTCTGACCAA
TCGGGAAATTGCGGAGGTGCTGTCCTTATCAAAGTTGACGGTCGAATGCCATATCAGAAACTCATACAAGAAACTGGCAG
TTCACTCCCGCACCCAGGCCGTCTTCGAGGCGCGTGCCTCTGGCTTGTTGCGCTGA

Upstream 100 bases:

>100_bases
CATGACCTCGTCCGGAATCGTCCGGACGTTCGCCAAGCCCGGCGGCAGTACGGCTACACTCAGGCCGCGCCCCCACCACT
GTCACTCCATGATCCAACCC

Downstream 100 bases:

>100_bases
TCTGCGGCGTCGTGCTGCTTGCCGGCGCAGCTAGCGCCCGGGCGCAATCGGAGGCCGTCGCCTTTACCCGAATCGAAGCC
GCACAGTCGACCTGGCAGGA

Product: LuxR family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MPDTAESVLPAPLLVVEDEPPMQSRLRTILAALGYGDDAIWFAGSLEAANTLLATQPFAMALVDVGLPDGNGIDLIRVMH
EQDPALPILVISTWNTERVIVSALQAGATGYLLKERDDVEIILSIRSALRGGAPIDPFVARRILDLAGKMAPLAGGAEVQ
AGPTVGAPPLSAREIEILSLVSKGLTNREIAEVLSLSKLTVECHIRNSYKKLAVHSRTQAVFEARASGLLR

Sequences:

>Translated_231_residues
MPDTAESVLPAPLLVVEDEPPMQSRLRTILAALGYGDDAIWFAGSLEAANTLLATQPFAMALVDVGLPDGNGIDLIRVMH
EQDPALPILVISTWNTERVIVSALQAGATGYLLKERDDVEIILSIRSALRGGAPIDPFVARRILDLAGKMAPLAGGAEVQ
AGPTVGAPPLSAREIEILSLVSKGLTNREIAEVLSLSKLTVECHIRNSYKKLAVHSRTQAVFEARASGLLR
>Mature_230_residues
PDTAESVLPAPLLVVEDEPPMQSRLRTILAALGYGDDAIWFAGSLEAANTLLATQPFAMALVDVGLPDGNGIDLIRVMHE
QDPALPILVISTWNTERVIVSALQAGATGYLLKERDDVEIILSIRSALRGGAPIDPFVARRILDLAGKMAPLAGGAEVQA
GPTVGAPPLSAREIEILSLVSKGLTNREIAEVLSLSKLTVECHIRNSYKKLAVHSRTQAVFEARASGLLR

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=211, Percent_Identity=28.9099526066351, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788222, Length=217, Percent_Identity=26.7281105990783, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24602; Mature: 24471

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTAESVLPAPLLVVEDEPPMQSRLRTILAALGYGDDAIWFAGSLEAANTLLATQPFAM
CCCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHCCCHHH
ALVDVGLPDGNGIDLIRVMHEQDPALPILVISTWNTERVIVSALQAGATGYLLKERDDVE
HHEEECCCCCCCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEECCCCHH
IILSIRSALRGGAPIDPFVARRILDLAGKMAPLAGGAEVQAGPTVGAPPLSAREIEILSL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHH
VSKGLTNREIAEVLSLSKLTVECHIRNSYKKLAVHSRTQAVFEARASGLLR
HHCCCCHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PDTAESVLPAPLLVVEDEPPMQSRLRTILAALGYGDDAIWFAGSLEAANTLLATQPFAM
CCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHCCCHHH
ALVDVGLPDGNGIDLIRVMHEQDPALPILVISTWNTERVIVSALQAGATGYLLKERDDVE
HHEEECCCCCCCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEECCCCHH
IILSIRSALRGGAPIDPFVARRILDLAGKMAPLAGGAEVQAGPTVGAPPLSAREIEILSL
HHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHH
VSKGLTNREIAEVLSLSKLTVECHIRNSYKKLAVHSRTQAVFEARASGLLR
HHCCCCHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]