Click here to switch to the map view.

The map label for this gene is fadR [H]

Identifier: 94309556

GI number: 94309556

Start: 665546

End: 666292

Strand: Direct

Name: fadR [H]

Synonym: Rmet_0611

Alternate gene names: 94309556

Gene position: 665546-666292 (Clockwise)

Preceding gene: 94309549

Following gene: 94309557

Centisome position: 16.94

GC content: 68.81

Gene sequence:

>747_bases
ATGCAGCAGATCGTGAATCAGCGTCGTATCCCGGCAGGCGCCAAGGCGGAGCAGCGTATTCGCGACATCCTGCGCGTGGG
CCGCGAAGTGTTCTCGGAGCTTGGCTACGAGCGGGCGACCACGACCGAGATCGCGCAGCGCCTGGGGATTTCCGAGGGCA
CGATCTTCACGTACTTCCACAGCAAGCGGGACCTGTGTGTCCGCGTGATCCAGGACTGGTACGACGAGATCATCGCGGCG
ATGGAGGGCGGCATGCCGCGCGAGGGCACCGCCCGGGCGCAACTGGAGTTTTTTATCGGCACGCACCTCCGGCTGTTCCT
GATCCATGGCACCGGCCTGTGCGCGCTGGTGCTGTCGGAGGGGCGCGCCAAGGGGCAGGGGCTCGACGAGGTGTTCGTGC
CGTTGCAACGGCGCTACACGGCGCCGCTGATGGCGCTGCTGGCCGCCGCCCAGGCGGGCGGGGAGATCCGGGCCGACATG
CCGTTGCGGCTGATGCGTTCGGCCATTCTGGGGCCGATGGAGCATATTCTCTGGGATGCCATCGTGAGCGGCCGCCCGGT
CGACATCGACCGCACCACGCAGGACATGATCGCGCTGCTGTGGCCCGCGCTGCAGCCGCAGAACCTGCAGGCCGCCGCGC
TGGGGCAGTTCTATGGCGAGGTCAGCGCGGCGCTGGCCCGGGTGCAGGCGGCGGGAGGGACGGCGGGCTCCGCTGAAGGC
TCCGCCGAGGGTTCCGAAGCTTCCTGA

Upstream 100 bases:

>100_bases
TCAACTTTCGGGCGCGCGCGGTCGGACAGGCGTGCCGAGCGCCGCTCGCGCCCTATAATTCCGGGCCATCACCGTTCAGG
TTACGCAACAGGGACCGCAA

Downstream 100 bases:

>100_bases
CGCCGCTTCGCCGGCATCCCCGGCTACCTGTATTCGGGGATGCCACATCCGGCCCGTTTCTGGCAGGCTGCCATGACCTC
GTCCGGAATCGTCCGGACGT

Product: TetR/AcrR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MQQIVNQRRIPAGAKAEQRIRDILRVGREVFSELGYERATTTEIAQRLGISEGTIFTYFHSKRDLCVRVIQDWYDEIIAA
MEGGMPREGTARAQLEFFIGTHLRLFLIHGTGLCALVLSEGRAKGQGLDEVFVPLQRRYTAPLMALLAAAQAGGEIRADM
PLRLMRSAILGPMEHILWDAIVSGRPVDIDRTTQDMIALLWPALQPQNLQAAALGQFYGEVSAALARVQAAGGTAGSAEG
SAEGSEAS

Sequences:

>Translated_248_residues
MQQIVNQRRIPAGAKAEQRIRDILRVGREVFSELGYERATTTEIAQRLGISEGTIFTYFHSKRDLCVRVIQDWYDEIIAA
MEGGMPREGTARAQLEFFIGTHLRLFLIHGTGLCALVLSEGRAKGQGLDEVFVPLQRRYTAPLMALLAAAQAGGEIRADM
PLRLMRSAILGPMEHILWDAIVSGRPVDIDRTTQDMIALLWPALQPQNLQAAALGQFYGEVSAALARVQAAGGTAGSAEG
SAEGSEAS
>Mature_248_residues
MQQIVNQRRIPAGAKAEQRIRDILRVGREVFSELGYERATTTEIAQRLGISEGTIFTYFHSKRDLCVRVIQDWYDEIIAA
MEGGMPREGTARAQLEFFIGTHLRLFLIHGTGLCALVLSEGRAKGQGLDEVFVPLQRRYTAPLMALLAAAQAGGEIRADM
PLRLMRSAILGPMEHILWDAIVSGRPVDIDRTTQDMIALLWPALQPQNLQAAALGQFYGEVSAALARVQAAGGTAGSAEG
SAEGSEAS

Specific function: Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifical

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- InterPro:   IPR013570 [H]

Pfam domain/function: PF08359 TetR_C_4; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 27005; Mature: 27005

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQIVNQRRIPAGAKAEQRIRDILRVGREVFSELGYERATTTEIAQRLGISEGTIFTYFH
CCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEC
SKRDLCVRVIQDWYDEIIAAMEGGMPREGTARAQLEFFIGTHLRLFLIHGTGLCALVLSE
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEEEEEECCCHHHHHHHC
GRAKGQGLDEVFVPLQRRYTAPLMALLAAAQAGGEIRADMPLRLMRSAILGPMEHILWDA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHH
IVSGRPVDIDRTTQDMIALLWPALQPQNLQAAALGQFYGEVSAALARVQAAGGTAGSAEG
HHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SAEGSEAS
CCCCCCCC
>Mature Secondary Structure
MQQIVNQRRIPAGAKAEQRIRDILRVGREVFSELGYERATTTEIAQRLGISEGTIFTYFH
CCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEC
SKRDLCVRVIQDWYDEIIAAMEGGMPREGTARAQLEFFIGTHLRLFLIHGTGLCALVLSE
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCEEEEEEECCCHHHHHHHC
GRAKGQGLDEVFVPLQRRYTAPLMALLAAAQAGGEIRADMPLRLMRSAILGPMEHILWDA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHH
IVSGRPVDIDRTTQDMIALLWPALQPQNLQAAALGQFYGEVSAALARVQAAGGTAGSAEG
HHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SAEGSEAS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]