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The map label for this gene is fdsG [H]

Identifier: 94309498

GI number: 94309498

Start: 590893

End: 591402

Strand: Direct

Name: fdsG [H]

Synonym: Rmet_0553

Alternate gene names: 94309498

Gene position: 590893-591402 (Clockwise)

Preceding gene: 94309496

Following gene: 94309499

Centisome position: 15.04

GC content: 68.43

Gene sequence:

>510_bases
ATGCCAGATACCATCCCCACCGGCGGTGACGCCGCGGGCGTTGCCGACGCCGTCGCACGCATCGTGGCCGCCCGGCGCGA
TATGCCAGGCGCGCTGCTGCCGATCCTGCACGACATCCAGGACAGCCAGGGTTTCATTCCGGCCGATGCGGTATCGGTCG
TCGCACGCGCGCTCAATCTGTCGCGCGCCGAGGTCCATGGCGTGATCACGTTCTATCACCACTTCCGCGAGCGGCCGGCT
GGCCGTACCGTGGTGCAGGTCTGTCGCGCAGAGGCTTGCCAGTCCGTCGGCGCCGACGCGCTTGCCGCCCATGCGCGCAA
GGCACTCGGGTGCGACTTCCACGAGACCACCGCGGATGGCCAGTTCACGCTCGAGCCGGTCTACTGCCTCGGCCAGTGCG
CCTGCGGCCCGGCAATGACGATCGGCGATCGTTTGCATGGGCGCGTCGACATGCAGCGATTCGACAAGCTGATCGACGCA
GTCCGCGAGCGCGAGGAGGCCCAGGCATGA

Upstream 100 bases:

>100_bases
AGTCGCACAAAGCGGCAAAAAAGCCAGCCTCGGTACCACCAAATATGTAGAAAAAAGCCGATATCGGTGGGTGCCGCAAA
ACGGTACGGAGACACAGTTC

Downstream 100 bases:

>100_bases
GCACGACGATCTTTGTACCCCGCGACTCCACCGCATTGGCGCTGGGCGCCGATGAAGTGGCGCAGGCCATCGCGCGCGAG
GCGGAAAAGCGCGGCGCGGA

Product: NAD-dependent formate dehydrogenase gamma subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E 2; NDH-1 subunit E 2 [H]

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MPDTIPTGGDAAGVADAVARIVAARRDMPGALLPILHDIQDSQGFIPADAVSVVARALNLSRAEVHGVITFYHHFRERPA
GRTVVQVCRAEACQSVGADALAAHARKALGCDFHETTADGQFTLEPVYCLGQCACGPAMTIGDRLHGRVDMQRFDKLIDA
VREREEAQA

Sequences:

>Translated_169_residues
MPDTIPTGGDAAGVADAVARIVAARRDMPGALLPILHDIQDSQGFIPADAVSVVARALNLSRAEVHGVITFYHHFRERPA
GRTVVQVCRAEACQSVGADALAAHARKALGCDFHETTADGQFTLEPVYCLGQCACGPAMTIGDRLHGRVDMQRFDKLIDA
VREREEAQA
>Mature_168_residues
PDTIPTGGDAAGVADAVARIVAARRDMPGALLPILHDIQDSQGFIPADAVSVVARALNLSRAEVHGVITFYHHFRERPAG
RTVVQVCRAEACQSVGADALAAHARKALGCDFHETTADGQFTLEPVYCLGQCACGPAMTIGDRLHGRVDMQRFDKLIDAV
REREEAQA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=152, Percent_Identity=30.9210526315789, Blast_Score=88, Evalue=3e-18,
Organism=Escherichia coli, GI1788621, Length=152, Percent_Identity=29.6052631578947, Blast_Score=82, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561328, Length=133, Percent_Identity=34.5864661654135, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21355353, Length=134, Percent_Identity=32.089552238806, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI18859877, Length=133, Percent_Identity=31.5789473684211, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18074; Mature: 17943

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTIPTGGDAAGVADAVARIVAARRDMPGALLPILHDIQDSQGFIPADAVSVVARALNL
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
SRAEVHGVITFYHHFRERPAGRTVVQVCRAEACQSVGADALAAHARKALGCDFHETTADG
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCC
QFTLEPVYCLGQCACGPAMTIGDRLHGRVDMQRFDKLIDAVREREEAQA
CEEEHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PDTIPTGGDAAGVADAVARIVAARRDMPGALLPILHDIQDSQGFIPADAVSVVARALNL
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
SRAEVHGVITFYHHFRERPAGRTVVQVCRAEACQSVGADALAAHARKALGCDFHETTADG
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCC
QFTLEPVYCLGQCACGPAMTIGDRLHGRVDMQRFDKLIDAVREREEAQA
CEEEHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]