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The map label for this gene is ywlC [H]

Identifier: 94309452

GI number: 94309452

Start: 537781

End: 538773

Strand: Direct

Name: ywlC [H]

Synonym: Rmet_0507

Alternate gene names: 94309452

Gene position: 537781-538773 (Clockwise)

Preceding gene: 94309451

Following gene: 94309455

Centisome position: 13.69

GC content: 68.48

Gene sequence:

>993_bases
ATGTCTTCACGTATGCCCACCGCCGCGGAGCTGGACGAAGCCGTCCGCCTGCTCGAAGCCGGCGAGCTGGTGGCCTTCCC
GACCGAGACCGTCTACGGTCTCGGTGCCGATGCCGAGAATCCTGAAGCCGTGGCGCGTATCTTCGCCGCCAAGGGCCGTC
CGTCGAACCATCCGGTGATCGTTCACGTGGTCGATGGCGCCGATGTCGGCTACTGGAGCGACGACGTACCCGAAGCCGCG
CAGAAGCTGATCGATGCGTTCTGGCCCGGTCCGCTGACGATCATCCTGAAACGCGCCGCCCACATCCCGGCAGCGGTTGC
CGGTGGGCAGGACAGCATCGGCTTGCGCTGCCCGTCGCATCCGGTGGCGCAGGCACTGCTGTCGCGCTTCCGCCGTGGCC
GGGGTGGCATTGCTGCGCCATCGGCCAACAAGTTCGGCCAGGTCAGCCCGACCACGGCCGAGCATGTGCGCGACGAGTTC
GGTGGATCGGTCTATGTGCTCGAAGGCGATGGCGTGGACGTTGGCATCGAATCGTCGATCGTCGATCTGTCCCGCCTGGA
TACGGCTGGCCCGGTGCTGCTGCGCCCGGGCGCGATCACGGCGGCGATGATGGCCGACGTGCTCGGCACCATGCCGCTAC
CGCCGGACGCCGCCGCGCCGCGCGCGTCGGGCACGCTCAAGGCCCATTACGCGCCCCGCACCACGCTGACGCTGGCCCAG
GCCGATGCCTTGCCGCAGTACCTGCATGGGCTGTCCGCCGATGGCAGGCTGGCTTGGGTGGGTCGCGCGCCGGCAACCAG
CGATCCGCGCTGCACGTTCGTTGAAGCACCGGCCACGCCGGATGCTTACGCGCAGGAGTTGTACCGGCTGTTGCGCCGGC
TCGACAAGGAAGGATTCCAGCGGCTGGTGTTCGAACCCTTGCCGGAGAGTCTCGAATGGGACGGGGTGCGGGACCGGTTG
GGTCGCGCCGCGGCTGCGTTCGAGGATTGCTGA

Upstream 100 bases:

>100_bases
GCACGTGAACTGCGTTGGCGACCACGCCGAAGCGGCCGACCGCACGTTCGATGCCGCCGCCAAGGCGCTGCACATCCCCA
GCTGAAACCGGTAGTTCGCG

Downstream 100 bases:

>100_bases
GGTTGGGGGAAGGCGAGGGGAAGGCCAGGCGCTCCATCCCCCACCACGCCTGTCACAAGACCCTCACCTCAAGGCGTGCC
CTTATACACCCACTGCATCA

Product: putative translation factor (SUA5)

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MSSRMPTAAELDEAVRLLEAGELVAFPTETVYGLGADAENPEAVARIFAAKGRPSNHPVIVHVVDGADVGYWSDDVPEAA
QKLIDAFWPGPLTIILKRAAHIPAAVAGGQDSIGLRCPSHPVAQALLSRFRRGRGGIAAPSANKFGQVSPTTAEHVRDEF
GGSVYVLEGDGVDVGIESSIVDLSRLDTAGPVLLRPGAITAAMMADVLGTMPLPPDAAAPRASGTLKAHYAPRTTLTLAQ
ADALPQYLHGLSADGRLAWVGRAPATSDPRCTFVEAPATPDAYAQELYRLLRRLDKEGFQRLVFEPLPESLEWDGVRDRL
GRAAAAFEDC

Sequences:

>Translated_330_residues
MSSRMPTAAELDEAVRLLEAGELVAFPTETVYGLGADAENPEAVARIFAAKGRPSNHPVIVHVVDGADVGYWSDDVPEAA
QKLIDAFWPGPLTIILKRAAHIPAAVAGGQDSIGLRCPSHPVAQALLSRFRRGRGGIAAPSANKFGQVSPTTAEHVRDEF
GGSVYVLEGDGVDVGIESSIVDLSRLDTAGPVLLRPGAITAAMMADVLGTMPLPPDAAAPRASGTLKAHYAPRTTLTLAQ
ADALPQYLHGLSADGRLAWVGRAPATSDPRCTFVEAPATPDAYAQELYRLLRRLDKEGFQRLVFEPLPESLEWDGVRDRL
GRAAAAFEDC
>Mature_329_residues
SSRMPTAAELDEAVRLLEAGELVAFPTETVYGLGADAENPEAVARIFAAKGRPSNHPVIVHVVDGADVGYWSDDVPEAAQ
KLIDAFWPGPLTIILKRAAHIPAAVAGGQDSIGLRCPSHPVAQALLSRFRRGRGGIAAPSANKFGQVSPTTAEHVRDEFG
GSVYVLEGDGVDVGIESSIVDLSRLDTAGPVLLRPGAITAAMMADVLGTMPLPPDAAAPRASGTLKAHYAPRTTLTLAQA
DALPQYLHGLSADGRLAWVGRAPATSDPRCTFVEAPATPDAYAQELYRLLRRLDKEGFQRLVFEPLPESLEWDGVRDRLG
RAAAAFEDC

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=212, Percent_Identity=31.1320754716981, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI2367210, Length=159, Percent_Identity=28.9308176100629, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87081864, Length=194, Percent_Identity=26.2886597938144, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6321269, Length=212, Percent_Identity=38.2075471698113, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 34972; Mature: 34841

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRMPTAAELDEAVRLLEAGELVAFPTETVYGLGADAENPEAVARIFAAKGRPSNHPVI
CCCCCCCHHHHHHHHHHHHCCCEEEECCHHHEECCCCCCCHHHHHHHHHHCCCCCCCCEE
VHVVDGADVGYWSDDVPEAAQKLIDAFWPGPLTIILKRAAHIPAAVAGGQDSIGLRCPSH
EEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCC
PVAQALLSRFRRGRGGIAAPSANKFGQVSPTTAEHVRDEFGGSVYVLEGDGVDVGIESSI
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCHHH
VDLSRLDTAGPVLLRPGAITAAMMADVLGTMPLPPDAAAPRASGTLKAHYAPRTTLTLAQ
HHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEHHH
ADALPQYLHGLSADGRLAWVGRAPATSDPRCTFVEAPATPDAYAQELYRLLRRLDKEGFQ
HHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
RLVFEPLPESLEWDGVRDRLGRAAAAFEDC
HHHHHCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSRMPTAAELDEAVRLLEAGELVAFPTETVYGLGADAENPEAVARIFAAKGRPSNHPVI
CCCCCCHHHHHHHHHHHHCCCEEEECCHHHEECCCCCCCHHHHHHHHHHCCCCCCCCEE
VHVVDGADVGYWSDDVPEAAQKLIDAFWPGPLTIILKRAAHIPAAVAGGQDSIGLRCPSH
EEEECCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCC
PVAQALLSRFRRGRGGIAAPSANKFGQVSPTTAEHVRDEFGGSVYVLEGDGVDVGIESSI
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCCCCCCHHH
VDLSRLDTAGPVLLRPGAITAAMMADVLGTMPLPPDAAAPRASGTLKAHYAPRTTLTLAQ
HHHHHCCCCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEHHH
ADALPQYLHGLSADGRLAWVGRAPATSDPRCTFVEAPATPDAYAQELYRLLRRLDKEGFQ
HHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
RLVFEPLPESLEWDGVRDRLGRAAAAFEDC
HHHHHCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]