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The map label for this gene is erpA [H]

Identifier: 94309359

GI number: 94309359

Start: 439723

End: 440091

Strand: Direct

Name: erpA [H]

Synonym: Rmet_0414

Alternate gene names: 94309359

Gene position: 439723-440091 (Clockwise)

Preceding gene: 94309358

Following gene: 94309362

Centisome position: 11.19

GC content: 57.99

Gene sequence:

>369_bases
ATGAACGCAGTCGCAGAGGCACCCGCAACCGAGGACGTGCCGGCACCGTTCGTCTTTACCGACAGCGCAGCCGACAAGGT
CAAGCAGTTGATCGAGGAAGAGGGCAATGCCGAACTGAAGCTGCGCGTGTTTGTGCAGGGTGGCGGCTGCTCGGGCTTCC
AGTACGGCTTCACCTTCGATGAAGATGTGAACGAAGACGACACCACGATGGTCAAGAACGGCGTCACGCTGTTGATTGAC
TCGATGAGCTACCAGTATCTGGTGGGCGCCGAGATCGACTACAAGGAAGACATCAACGGTGCGCAGTTCGTGATCAAGAA
CCCGAACGCATCGACCACCTGCGGTTGCGGTTCGTCGTTCTCGGTCTGA

Upstream 100 bases:

>100_bases
AGCGGTACCCCGAGGGCCCAGAGCCCCTTGAAAACAAGGGGTTTCGGCACGATTTGCCAGTAACGCTTAGAATACGGGCG
TATCTAACCAGGAGATTCCC

Downstream 100 bases:

>100_bases
GCCGGGTTCGTCCCCCAAAGAAAAAGCGCACCAGTCGGTGCGCTTTTTTTGTTTTCGGGCCGTCGAAAATCCGACCGGAT
CAGCGTGCAGCCTATCTCGG

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MNAVAEAPATEDVPAPFVFTDSAADKVKQLIEEEGNAELKLRVFVQGGGCSGFQYGFTFDEDVNEDDTTMVKNGVTLLID
SMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSFSV

Sequences:

>Translated_122_residues
MNAVAEAPATEDVPAPFVFTDSAADKVKQLIEEEGNAELKLRVFVQGGGCSGFQYGFTFDEDVNEDDTTMVKNGVTLLID
SMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSFSV
>Mature_122_residues
MNAVAEAPATEDVPAPFVFTDSAADKVKQLIEEEGNAELKLRVFVQGGGCSGFQYGFTFDEDVNEDDTTMVKNGVTLLID
SMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSFSV

Specific function: Required for insertion of 4Fe-4S clusters (Potential) [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=105, Percent_Identity=40.9523809523809, Blast_Score=84, Evalue=3e-17,
Organism=Homo sapiens, GI52426768, Length=108, Percent_Identity=34.2592592592593, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786351, Length=113, Percent_Identity=61.0619469026549, Blast_Score=153, Evalue=3e-39,
Organism=Escherichia coli, GI1788877, Length=105, Percent_Identity=36.1904761904762, Blast_Score=66, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71998452, Length=105, Percent_Identity=39.0476190476191, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25146411, Length=116, Percent_Identity=30.1724137931034, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193209025, Length=108, Percent_Identity=31.4814814814815, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323001, Length=97, Percent_Identity=37.1134020618557, Blast_Score=70, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=46.9879518072289, Blast_Score=81, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24642263, Length=108, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 13096; Mature: 13096

Theoretical pI: Translated: 3.77; Mature: 3.77

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAVAEAPATEDVPAPFVFTDSAADKVKQLIEEEGNAELKLRVFVQGGGCSGFQYGFTFD
CCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCEECCCEEC
EDVNEDDTTMVKNGVTLLIDSMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSF
CCCCCCCCEEECCCEEEEEECCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC
SV
CC
>Mature Secondary Structure
MNAVAEAPATEDVPAPFVFTDSAADKVKQLIEEEGNAELKLRVFVQGGGCSGFQYGFTFD
CCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCEECCCEEC
EDVNEDDTTMVKNGVTLLIDSMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSF
CCCCCCCCEEECCCEEEEEECCCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCC
SV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA