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The map label for this gene is aspC [H]

Identifier: 94309291

GI number: 94309291

Start: 364800

End: 365999

Strand: Direct

Name: aspC [H]

Synonym: Rmet_0346

Alternate gene names: 94309291

Gene position: 364800-365999 (Clockwise)

Preceding gene: 94309290

Following gene: 94309297

Centisome position: 9.29

GC content: 67.0

Gene sequence:

>1200_bases
ATGTCGACCAGCCCGTCCCGCCAGTCTTCCCTGACCGAAGCGCCGCCACGGGCGCGTGACGTCGTGCACGCGCTGCGCGC
GTCGCGCATCCGTGAAGTGGCTAATGCAGGGATCGGCCTGCCCGACGTGCTGCCGTTCTGGTTCGGTGAATCGGACCAGG
TCACGCCGTCATTCATCCGCGATGCCGCGAGCCGCGCGCTCGCAAACGGGGCCACCTTCTACAACCACAATCTTGGCATC
GCGCCGCTGCGGGCGGCGTTGTCGGAGTACGTGACCCGATTGCACGGAGCCACGCCGGTCGACCATATCGCCGTGACCAG
CGCCGGCGTCAATGCGCTGATGCTCGCCGCGCAACTCGTCACCGGCCCCGGCGACCGCGTGGTGGCGGTGACGCCGCTGT
GGCCCAACCTCGTCGAGATTCCGCGCATCCTTGGCGCGGCGGTGGAAACAGTGACGCTCGACTATGGCGCGGATGGCTGG
ACACTCGATGTCGACAAGCTGCTGGCCGCGCTGACGCCGGGCACGCGCGCCGTGATGATCAATTCGCCGAACAACCCGAC
CGGCTGGGTCATGCCCCGCGGCGCGCAACAGGCCGTGCTCGACCACTGCCGCCGCCACGGCATCTGGATCATCGCCGACG
AAGTCTACGAGCGGCTTTACTACGGCGACGAGGGGGCGGTCGCACCATCGTTCCTTGACATCGCCGGCCGCGACGAGCGC
GTTATCGCGGTCAACTCGTTCTCGAAGGCATGGCTGATGACCGGCTGGCGGCTTGGCTGGATGGTGGTGCCATCTTCGAT
GATGGACGACCTGGGCAAGCTCATCGAATACAACACGTCCTGCGCGCCATCGTTCGTGCAGGAGGCCGGCGTGGTGGCCG
TGCGTGAGGGCGAAGCATTCACCCAGGATCTGGTCAAACGGCTGCGTTCGGCGCGTGATCATCTGGTGAGCGCGCTATCG
GCATTACCCGGTATCGACGCGCACGCGCCGGATGGGGCGATGTATGTGTTCTTCCGCCTGAAAGGCGCGACCGACAGCCT
CGATCTGTGCAAGCGGCTCGTGCGCGATGCCCATCTCGGGCTGGCGCCGGGAAGCGCGTTCGGCGACGAGGGCGAGGGCT
TTGTGCGGTGGTGCTATGCGTGCGACGAGGCGCGGCTCGATGAGGGGGTGAAGCGGTTGCGGGGGTATCTGGGGCGGTAG

Upstream 100 bases:

>100_bases
GCGAGCGTTTCGCGGACTGAAAAAGCCCTCTGGCGACGACAGCAGGGCGGGGCGGATTCCGGTACGCTAGGCGTTTCATC
GTTCCCCCGAAGGAGTGCCG

Downstream 100 bases:

>100_bases
CGGTTGATGGGCCTGACCCTCTGGCTCGGCCCCTCCCGCGCTAACGATCCGCTAACGATCGCTAACCACCTCTATTTCAA
ACTCCCCACCGTTTCCGACT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSTSPSRQSSLTEAPPRARDVVHALRASRIREVANAGIGLPDVLPFWFGESDQVTPSFIRDAASRALANGATFYNHNLGI
APLRAALSEYVTRLHGATPVDHIAVTSAGVNALMLAAQLVTGPGDRVVAVTPLWPNLVEIPRILGAAVETVTLDYGADGW
TLDVDKLLAALTPGTRAVMINSPNNPTGWVMPRGAQQAVLDHCRRHGIWIIADEVYERLYYGDEGAVAPSFLDIAGRDER
VIAVNSFSKAWLMTGWRLGWMVVPSSMMDDLGKLIEYNTSCAPSFVQEAGVVAVREGEAFTQDLVKRLRSARDHLVSALS
ALPGIDAHAPDGAMYVFFRLKGATDSLDLCKRLVRDAHLGLAPGSAFGDEGEGFVRWCYACDEARLDEGVKRLRGYLGR

Sequences:

>Translated_399_residues
MSTSPSRQSSLTEAPPRARDVVHALRASRIREVANAGIGLPDVLPFWFGESDQVTPSFIRDAASRALANGATFYNHNLGI
APLRAALSEYVTRLHGATPVDHIAVTSAGVNALMLAAQLVTGPGDRVVAVTPLWPNLVEIPRILGAAVETVTLDYGADGW
TLDVDKLLAALTPGTRAVMINSPNNPTGWVMPRGAQQAVLDHCRRHGIWIIADEVYERLYYGDEGAVAPSFLDIAGRDER
VIAVNSFSKAWLMTGWRLGWMVVPSSMMDDLGKLIEYNTSCAPSFVQEAGVVAVREGEAFTQDLVKRLRSARDHLVSALS
ALPGIDAHAPDGAMYVFFRLKGATDSLDLCKRLVRDAHLGLAPGSAFGDEGEGFVRWCYACDEARLDEGVKRLRGYLGR
>Mature_398_residues
STSPSRQSSLTEAPPRARDVVHALRASRIREVANAGIGLPDVLPFWFGESDQVTPSFIRDAASRALANGATFYNHNLGIA
PLRAALSEYVTRLHGATPVDHIAVTSAGVNALMLAAQLVTGPGDRVVAVTPLWPNLVEIPRILGAAVETVTLDYGADGWT
LDVDKLLAALTPGTRAVMINSPNNPTGWVMPRGAQQAVLDHCRRHGIWIIADEVYERLYYGDEGAVAPSFLDIAGRDERV
IAVNSFSKAWLMTGWRLGWMVVPSSMMDDLGKLIEYNTSCAPSFVQEAGVVAVREGEAFTQDLVKRLRSARDHLVSALSA
LPGIDAHAPDGAMYVFFRLKGATDSLDLCKRLVRDAHLGLAPGSAFGDEGEGFVRWCYACDEARLDEGVKRLRGYLGR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=413, Percent_Identity=24.9394673123487, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI169881279, Length=413, Percent_Identity=24.9394673123487, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI56713254, Length=402, Percent_Identity=26.6169154228856, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI56713256, Length=402, Percent_Identity=26.6169154228856, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI4507369, Length=411, Percent_Identity=22.8710462287105, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI169881281, Length=266, Percent_Identity=25.9398496240602, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI19263340, Length=369, Percent_Identity=24.1192411924119, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI215599424, Length=369, Percent_Identity=24.1192411924119, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1786816, Length=345, Percent_Identity=26.6666666666667, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788722, Length=366, Percent_Identity=25.4098360655738, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788627, Length=364, Percent_Identity=26.9230769230769, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787909, Length=365, Percent_Identity=25.7534246575342, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790797, Length=371, Percent_Identity=24.7978436657682, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1787710, Length=323, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17567663, Length=339, Percent_Identity=24.4837758112094, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17567369, Length=388, Percent_Identity=23.1958762886598, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=443, Percent_Identity=23.9277652370203, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71994476, Length=406, Percent_Identity=23.6453201970443, Blast_Score=95, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6322401, Length=334, Percent_Identity=23.0538922155689, Blast_Score=96, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6320317, Length=364, Percent_Identity=24.4505494505494, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28573069, Length=353, Percent_Identity=24.0793201133144, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24646114, Length=353, Percent_Identity=24.0793201133144, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28573067, Length=353, Percent_Identity=24.0793201133144, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28573065, Length=353, Percent_Identity=24.0793201133144, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI18859735, Length=408, Percent_Identity=23.0392156862745, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43177; Mature: 43045

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSPSRQSSLTEAPPRARDVVHALRASRIREVANAGIGLPDVLPFWFGESDQVTPSFIR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHH
DAASRALANGATFYNHNLGIAPLRAALSEYVTRLHGATPVDHIAVTSAGVNALMLAAQLV
HHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHEEECCCHHHHHHHHHHH
TGPGDRVVAVTPLWPNLVEIPRILGAAVETVTLDYGADGWTLDVDKLLAALTPGTRAVMI
CCCCCCEEEECCCCCCHHHHHHHHHHHHHEEEEECCCCCCEEEHHHHHHHHCCCCEEEEE
NSPNNPTGWVMPRGAQQAVLDHCRRHGIWIIADEVYERLYYGDEGAVAPSFLDIAGRDER
ECCCCCCCCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCCCCCHHHHHCCCCCE
VIAVNSFSKAWLMTGWRLGWMVVPSSMMDDLGKLIEYNTSCAPSFVQEAGVVAVREGEAF
EEEECCCCHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEECCCHH
TQDLVKRLRSARDHLVSALSALPGIDAHAPDGAMYVFFRLKGATDSLDLCKRLVRDAHLG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCC
LAPGSAFGDEGEGFVRWCYACDEARLDEGVKRLRGYLGR
CCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STSPSRQSSLTEAPPRARDVVHALRASRIREVANAGIGLPDVLPFWFGESDQVTPSFIR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHH
DAASRALANGATFYNHNLGIAPLRAALSEYVTRLHGATPVDHIAVTSAGVNALMLAAQLV
HHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHEEECCCHHHHHHHHHHH
TGPGDRVVAVTPLWPNLVEIPRILGAAVETVTLDYGADGWTLDVDKLLAALTPGTRAVMI
CCCCCCEEEECCCCCCHHHHHHHHHHHHHEEEEECCCCCCEEEHHHHHHHHCCCCEEEEE
NSPNNPTGWVMPRGAQQAVLDHCRRHGIWIIADEVYERLYYGDEGAVAPSFLDIAGRDER
ECCCCCCCCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCCCCCHHHHHCCCCCE
VIAVNSFSKAWLMTGWRLGWMVVPSSMMDDLGKLIEYNTSCAPSFVQEAGVVAVREGEAF
EEEECCCCHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEECCCHH
TQDLVKRLRSARDHLVSALSALPGIDAHAPDGAMYVFFRLKGATDSLDLCKRLVRDAHLG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCC
LAPGSAFGDEGEGFVRWCYACDEARLDEGVKRLRGYLGR
CCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]