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The map label for this gene is yodT [H]

Identifier: 94309289

GI number: 94309289

Start: 362513

End: 363838

Strand: Direct

Name: yodT [H]

Synonym: Rmet_0344

Alternate gene names: 94309289

Gene position: 362513-363838 (Clockwise)

Preceding gene: 94309287

Following gene: 94309290

Centisome position: 9.23

GC content: 65.99

Gene sequence:

>1326_bases
ATGACGCACGTATTCCACCGCAATCCGAAGCAAACCTTGCCGGTCGCCGTTGGCGGCCAGGGTATCGAACTGATCGACAG
CAATGGCCGGCGCTACCTCGACGCTTCGGGCGGCGCGGCGGTTTCCTGTCTCGGTCATGGCCACCCGCGCGTGATCGAAG
CGATCAAGGCGCAGGTGGACACCATTGCCTACGCGCATACGTCGTTCTTTACCACCGAGGTGTCCGAGACGCTGGCCCAG
ACGCTGGCCGATGCGGCCCCCGGAGATCTCGATCATGTGTACTTCGTGTCCGGCGGCTCCGAGGCGGTGGAAGCCGCGCT
GAAGCTGGCGCGCCAGTACTTCGTGGAGATCGGCCAGACGCAGCGCCGCCACTTCATCGCGCGGCGCCAGAGCTATCACG
GCAATACGCTCGGCGCGCTGGCGATCGGCGGCAACGCGTGGCGGCGCGAGCCGTTCCTGCCGCTGCTGGTGCCGGCGCAC
CATGTGTCGCCGTGCTATGCCTACCGAGATCAGGCGGCCGGCGAAGCCGACACGCAGTACGCGCAGCGTCTGGCCGACGA
ACTTGAAGCAAAGATCCTCGAACTCGGCCCCGACTCGGTGGCCGGCTTCGTCGCCGAGACGGTGGTCGGCGCTACCGCAG
GGGCGGTGCCGCCGGTGGCCGATTACCTGAAGCGTATCCGCGCTGTGTGCGACAAGTACGGCGTGCTGCTGATCCTCGAT
GAAGTGATGTCGGGCATGGGCCGGACGGGTTACCTGTTCGCGTGCGAAGAGGACGGCGTGGTGCCCGACATCGTGACGAT
CGCGAAGGGCCTCGGCGCTGGTTACCAGCCGATCGGCGCAATGCTCTCGACGTCGCGCATCTATGACGCGATCATCGGTG
GCAGCGGTTTCTTCCAGCACGGCCACACCTATATCGGTCATGCGACGGCCTGCGCGGCAGCGCTGGCCGTGCAGCGCACG
ATTGTCGAGGACAAGTTGCTGGACAACGTGCTGGCGCGTGGCGAACAGTTGCGCGCGCGCCTGCGCGAATCGCTCGGCGA
CCATCCGAACCTTGGCGACGTGCGGGGCCGTGGACTGTTCGTCGGCGTGGAGTTCGTGGCCGATCGCGCCACCAAGGCCA
CGCTCGACCCGGCGAAGAAGACGCACGCCGTGCTCAAGCGCACCTGCATGGAGCATGGCGTGCTGGTTTATCCGATGGGC
GGCACGGTCGATGGCATCCACGGTGACCACGTGCTGTTTGCGCCGCCGTTTATCTGCACGCCCACCGACATCGACAACAT
CGTAGACCGCTTCACGCAGGCCGTGAAAACGGTACTGCCGGCTTGA

Upstream 100 bases:

>100_bases
TTCGTGCTGGTGCCTTAATGAAACACTTGTTGCGCTGCCGGGACGTTGTTCCTATACTCACACCTGTTTCCGGGCAGACC
CCCGCATCCCGCACCTCACC

Downstream 100 bases:

>100_bases
GGAGCGCGACGATGCCGAACCAGAATCCTGTCGCTACCGCTGACACCTTGCGTCGCCCGTTCGCTCTGGCGGTGGCCCCG
AATGGCGCGCGCAAGACGCA

Product: hypothetical protein

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MTHVFHRNPKQTLPVAVGGQGIELIDSNGRRYLDASGGAAVSCLGHGHPRVIEAIKAQVDTIAYAHTSFFTTEVSETLAQ
TLADAAPGDLDHVYFVSGGSEAVEAALKLARQYFVEIGQTQRRHFIARRQSYHGNTLGALAIGGNAWRREPFLPLLVPAH
HVSPCYAYRDQAAGEADTQYAQRLADELEAKILELGPDSVAGFVAETVVGATAGAVPPVADYLKRIRAVCDKYGVLLILD
EVMSGMGRTGYLFACEEDGVVPDIVTIAKGLGAGYQPIGAMLSTSRIYDAIIGGSGFFQHGHTYIGHATACAAALAVQRT
IVEDKLLDNVLARGEQLRARLRESLGDHPNLGDVRGRGLFVGVEFVADRATKATLDPAKKTHAVLKRTCMEHGVLVYPMG
GTVDGIHGDHVLFAPPFICTPTDIDNIVDRFTQAVKTVLPA

Sequences:

>Translated_441_residues
MTHVFHRNPKQTLPVAVGGQGIELIDSNGRRYLDASGGAAVSCLGHGHPRVIEAIKAQVDTIAYAHTSFFTTEVSETLAQ
TLADAAPGDLDHVYFVSGGSEAVEAALKLARQYFVEIGQTQRRHFIARRQSYHGNTLGALAIGGNAWRREPFLPLLVPAH
HVSPCYAYRDQAAGEADTQYAQRLADELEAKILELGPDSVAGFVAETVVGATAGAVPPVADYLKRIRAVCDKYGVLLILD
EVMSGMGRTGYLFACEEDGVVPDIVTIAKGLGAGYQPIGAMLSTSRIYDAIIGGSGFFQHGHTYIGHATACAAALAVQRT
IVEDKLLDNVLARGEQLRARLRESLGDHPNLGDVRGRGLFVGVEFVADRATKATLDPAKKTHAVLKRTCMEHGVLVYPMG
GTVDGIHGDHVLFAPPFICTPTDIDNIVDRFTQAVKTVLPA
>Mature_440_residues
THVFHRNPKQTLPVAVGGQGIELIDSNGRRYLDASGGAAVSCLGHGHPRVIEAIKAQVDTIAYAHTSFFTTEVSETLAQT
LADAAPGDLDHVYFVSGGSEAVEAALKLARQYFVEIGQTQRRHFIARRQSYHGNTLGALAIGGNAWRREPFLPLLVPAHH
VSPCYAYRDQAAGEADTQYAQRLADELEAKILELGPDSVAGFVAETVVGATAGAVPPVADYLKRIRAVCDKYGVLLILDE
VMSGMGRTGYLFACEEDGVVPDIVTIAKGLGAGYQPIGAMLSTSRIYDAIIGGSGFFQHGHTYIGHATACAAALAVQRTI
VEDKLLDNVLARGEQLRARLRESLGDHPNLGDVRGRGLFVGVEFVADRATKATLDPAKKTHAVLKRTCMEHGVLVYPMGG
TVDGIHGDHVLFAPPFICTPTDIDNIVDRFTQAVKTVLPA

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=435, Percent_Identity=28.9655172413793, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI37574042, Length=436, Percent_Identity=30.045871559633, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI4557809, Length=432, Percent_Identity=28.0092592592593, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI226442705, Length=436, Percent_Identity=29.3577981651376, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI226442709, Length=409, Percent_Identity=29.8288508557457, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI24119277, Length=416, Percent_Identity=29.0865384615385, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI284507298, Length=343, Percent_Identity=28.8629737609329, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI145693181, Length=347, Percent_Identity=34.2939481268012, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1788044, Length=423, Percent_Identity=32.6241134751773, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1789759, Length=434, Percent_Identity=32.7188940092166, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1786991, Length=439, Percent_Identity=30.2961275626424, Blast_Score=172, Evalue=6e-44,
Organism=Escherichia coli, GI1789016, Length=368, Percent_Identity=32.8804347826087, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1787560, Length=433, Percent_Identity=28.175519630485, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1786349, Length=334, Percent_Identity=30.8383233532934, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71992977, Length=432, Percent_Identity=30.3240740740741, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI32564660, Length=437, Percent_Identity=32.2654462242563, Blast_Score=168, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI25144271, Length=448, Percent_Identity=27.9017857142857, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI25144274, Length=240, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6324432, Length=422, Percent_Identity=30.5687203791469, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6323470, Length=440, Percent_Identity=27.7272727272727, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6324386, Length=476, Percent_Identity=23.5294117647059, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21356575, Length=432, Percent_Identity=32.6388888888889, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI28574759, Length=436, Percent_Identity=30.9633027522936, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI161085790, Length=432, Percent_Identity=30.3240740740741, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI21357415, Length=436, Percent_Identity=28.8990825688073, Blast_Score=155, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 47201; Mature: 47070

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHVFHRNPKQTLPVAVGGQGIELIDSNGRRYLDASGGAAVSCLGHGHPRVIEAIKAQVD
CCCCCCCCCCCCCCEEECCCCEEEEECCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHH
TIAYAHTSFFTTEVSETLAQTLADAAPGDLDHVYFVSGGSEAVEAALKLARQYFVEIGQT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
QRRHFIARRQSYHGNTLGALAIGGNAWRREPFLPLLVPAHHVSPCYAYRDQAAGEADTQY
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEECHHHCCHHHHHHHHCCCCHHHHH
AQRLADELEAKILELGPDSVAGFVAETVVGATAGAVPPVADYLKRIRAVCDKYGVLLILD
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHEEHH
EVMSGMGRTGYLFACEEDGVVPDIVTIAKGLGAGYQPIGAMLSTSRIYDAIIGGSGFFQH
HHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHC
GHTYIGHATACAAALAVQRTIVEDKLLDNVLARGEQLRARLRESLGDHPNLGDVRGRGLF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEE
VGVEFVADRATKATLDPAKKTHAVLKRTCMEHGVLVYPMGGTVDGIHGDHVLFAPPFICT
EEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEECCCCEEC
PTDIDNIVDRFTQAVKTVLPA
CCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
THVFHRNPKQTLPVAVGGQGIELIDSNGRRYLDASGGAAVSCLGHGHPRVIEAIKAQVD
CCCCCCCCCCCCCEEECCCCEEEEECCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHH
TIAYAHTSFFTTEVSETLAQTLADAAPGDLDHVYFVSGGSEAVEAALKLARQYFVEIGQT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHH
QRRHFIARRQSYHGNTLGALAIGGNAWRREPFLPLLVPAHHVSPCYAYRDQAAGEADTQY
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEECHHHCCHHHHHHHHCCCCHHHHH
AQRLADELEAKILELGPDSVAGFVAETVVGATAGAVPPVADYLKRIRAVCDKYGVLLILD
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHEEHH
EVMSGMGRTGYLFACEEDGVVPDIVTIAKGLGAGYQPIGAMLSTSRIYDAIIGGSGFFQH
HHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHC
GHTYIGHATACAAALAVQRTIVEDKLLDNVLARGEQLRARLRESLGDHPNLGDVRGRGLF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEE
VGVEFVADRATKATLDPAKKTHAVLKRTCMEHGVLVYPMGGTVDGIHGDHVLFAPPFICT
EEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEECCCCEEC
PTDIDNIVDRFTQAVKTVLPA
CCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377 [H]