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The map label for this gene is ttuB [H]

Identifier: 94309286

GI number: 94309286

Start: 358986

End: 360347

Strand: Direct

Name: ttuB [H]

Synonym: Rmet_0341

Alternate gene names: 94309286

Gene position: 358986-360347 (Clockwise)

Preceding gene: 94309285

Following gene: 94309287

Centisome position: 9.14

GC content: 65.64

Gene sequence:

>1362_bases
ATGCATACCCAGAGCCTGGGCGCCGCCCCCGTCTTGCCTGAAATCCCGTCACACGCAATACCGCAAGTCCTTCCCACGCA
GCAGGAGGACGCGCTGTACCGCAAGGTCTGGCTGCGCATCATCCCGTTCCTGTTCATCTGCTACGTCGTGTCGTTCCTGG
ACCGGATCAACATCGGCTTCGCGCAATTGCAGATGAAGCATGACCTTGGGTTCAGTGACGCGATGTACGGGCTGGGCGCA
GCAGTGTTCTACGTCGGCTACGTGCTGTGCGAAGTCCCCAGCAACATGCTGTTGGCACGCTTTGGCGCGCGCCGCACGTT
CACGCGGATCATGCTGCTGTGGGGTGTCGCATCGGTGGGCATGATGCTGGTGTCGCAGCCGTCGCACTTCTATCTGCTGC
GCTTCCTGCTCGGCGTGTTCGAAGCGGGCTTCTTCCCGGGCATTGTGCTGTACCTGACCTACTGGTTCCCGGCGCGCCGT
CGCGCGGCGGTGATGGCGATCTTCTTTGCGGGCGTGGCCGTGGCCGGCGTGCTTGGCGGGCTGATCTCGGGCTGGATCAT
GCGCGACATGGCCGGTGTGCTTGGGATGCGCGGCTGGCAATGGATGTTCGCGATCGAAGGCGCGCCGGCAGTGCTGCTGG
GCCTGATCGCCGCCGTGTGCCTCGTCGATGGCCCACGCCAGGCGCGCTGGCTGACACCGGCCGAGCAGGACTACCTGGTG
GCCCAACATGAGGCGGAGTCGCGCGGTGCGGGTGGCCACGCCCATTCGATGCAGGCCCTGCGTCAGGCCCTGGCCAACCC
ACGGGTCTATCTGTTCGCGTTCATCTACTTCGCGCTGACGTGCGGCTCGCTGACGCTGTCATTCTGGATGCCGCTCATGA
TTCGCGACTTCGGCATCCAGGACGTGGTGGCCGTCAGCCTCTACTCGGTCATCCCGAACGCCATCGGCGCGGTGGGCTTG
ATCCTTATTGCGCGGCGCTCCGACCGCCTCGGCGAGCGTCACGGGCATTTTCTCTGCTGCACTGCAGGAGGCGCACTGGC
GCTGGCCGCGTTGACGCTACATGTGCCGAGCCTTGGCGTGTCGTTGGCGATCCTATCTGTTGCCGCCGTGCTGATCTTCG
CCGCGCTGCCGATCTTCTGGGCGCTGCCGCCAAGCCATCTGCCGGCCCAGACCGCCGCCACCGGCATTGCCTTCATCTCC
AGCATCGGTATCACCAGCGGCATCGTCAGCCCCTGGGTCATCGGCCAGATCAAGGCGCACACGGGCAGCATGGACAACGC
GCTGTACCTGTTGGCCGGGCTGCTGCTGGCCAGCGGGCTGGCGCTGTGGAAGGGCGTGCCGCGCACACCGACGGCGCACT
AG

Upstream 100 bases:

>100_bases
AGCCTGCCGCAAGCTAGCCACTTCATTCCTGCCCGCCAGTGACCCGACAGGGGCGCGACAGACGCCCCGGGGCCAACTCG
ACCCTATTCCGGAGACAACC

Downstream 100 bases:

>100_bases
CAGGGCGGTGTTCCCCGATACCGGGCGGTTCATGCCCGATATCGGGGAAAAATCATTTGTTTCATGGTTATCCATGATGG
AACACTTGTTGCTCTATGCC

Product: major facilitator superfamily transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MHTQSLGAAPVLPEIPSHAIPQVLPTQQEDALYRKVWLRIIPFLFICYVVSFLDRINIGFAQLQMKHDLGFSDAMYGLGA
AVFYVGYVLCEVPSNMLLARFGARRTFTRIMLLWGVASVGMMLVSQPSHFYLLRFLLGVFEAGFFPGIVLYLTYWFPARR
RAAVMAIFFAGVAVAGVLGGLISGWIMRDMAGVLGMRGWQWMFAIEGAPAVLLGLIAAVCLVDGPRQARWLTPAEQDYLV
AQHEAESRGAGGHAHSMQALRQALANPRVYLFAFIYFALTCGSLTLSFWMPLMIRDFGIQDVVAVSLYSVIPNAIGAVGL
ILIARRSDRLGERHGHFLCCTAGGALALAALTLHVPSLGVSLAILSVAAVLIFAALPIFWALPPSHLPAQTAATGIAFIS
SIGITSGIVSPWVIGQIKAHTGSMDNALYLLAGLLLASGLALWKGVPRTPTAH

Sequences:

>Translated_453_residues
MHTQSLGAAPVLPEIPSHAIPQVLPTQQEDALYRKVWLRIIPFLFICYVVSFLDRINIGFAQLQMKHDLGFSDAMYGLGA
AVFYVGYVLCEVPSNMLLARFGARRTFTRIMLLWGVASVGMMLVSQPSHFYLLRFLLGVFEAGFFPGIVLYLTYWFPARR
RAAVMAIFFAGVAVAGVLGGLISGWIMRDMAGVLGMRGWQWMFAIEGAPAVLLGLIAAVCLVDGPRQARWLTPAEQDYLV
AQHEAESRGAGGHAHSMQALRQALANPRVYLFAFIYFALTCGSLTLSFWMPLMIRDFGIQDVVAVSLYSVIPNAIGAVGL
ILIARRSDRLGERHGHFLCCTAGGALALAALTLHVPSLGVSLAILSVAAVLIFAALPIFWALPPSHLPAQTAATGIAFIS
SIGITSGIVSPWVIGQIKAHTGSMDNALYLLAGLLLASGLALWKGVPRTPTAH
>Mature_453_residues
MHTQSLGAAPVLPEIPSHAIPQVLPTQQEDALYRKVWLRIIPFLFICYVVSFLDRINIGFAQLQMKHDLGFSDAMYGLGA
AVFYVGYVLCEVPSNMLLARFGARRTFTRIMLLWGVASVGMMLVSQPSHFYLLRFLLGVFEAGFFPGIVLYLTYWFPARR
RAAVMAIFFAGVAVAGVLGGLISGWIMRDMAGVLGMRGWQWMFAIEGAPAVLLGLIAAVCLVDGPRQARWLTPAEQDYLV
AQHEAESRGAGGHAHSMQALRQALANPRVYLFAFIYFALTCGSLTLSFWMPLMIRDFGIQDVVAVSLYSVIPNAIGAVGL
ILIARRSDRLGERHGHFLCCTAGGALALAALTLHVPSLGVSLAILSVAAVLIFAALPIFWALPPSHLPAQTAATGIAFIS
SIGITSGIVSPWVIGQIKAHTGSMDNALYLLAGLLLASGLALWKGVPRTPTAH

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=442, Percent_Identity=34.841628959276, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1789152, Length=418, Percent_Identity=24.6411483253589, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87082320, Length=234, Percent_Identity=25.6410256410256, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI2367379, Length=381, Percent_Identity=25.1968503937008, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789515, Length=428, Percent_Identity=22.6635514018692, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI2367193, Length=268, Percent_Identity=22.3880597014925, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=205, Percent_Identity=29.7560975609756, Blast_Score=100, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6321698, Length=371, Percent_Identity=23.4501347708895, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6322612, Length=291, Percent_Identity=24.7422680412371, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319876, Length=173, Percent_Identity=27.1676300578035, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319250, Length=302, Percent_Identity=22.8476821192053, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324410, Length=167, Percent_Identity=23.3532934131737, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321502, Length=179, Percent_Identity=25.6983240223464, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583789, Length=367, Percent_Identity=23.433242506812, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584153, Length=377, Percent_Identity=21.2201591511936, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48920; Mature: 48920

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure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CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]