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The map label for this gene is crp1 [H]

Identifier: 94309158

GI number: 94309158

Start: 225859

End: 226638

Strand: Reverse

Name: crp1 [H]

Synonym: Rmet_0213

Alternate gene names: 94309158

Gene position: 226638-225859 (Counterclockwise)

Preceding gene: 94309166

Following gene: 94309153

Centisome position: 5.77

GC content: 60.64

Gene sequence:

>780_bases
ATGTGCTGGCAAAGGCCGGTTCCGCGTGATCGTAAGATAGCCGATGCCATCCCCCGGGGTTGTCACGCCGATGACAATTC
CGGGTTAATCCCTACGATTGAGATGACCGCCACCAACAACGACTTCATCGACCGATGCGCCTGGGCCACCAACCTGAGCC
CCGAACAACGCGCGCGTGTCAAACGCGTGACTACGGTGCGCGAGTACACCCAGGGCGAGTATGTCTGCCACAAGGGCGAG
ATGGCCGAGCACTGGCTCGGCGTCGTGGAAGGCGTGGTCAAGATCACAACTGTCTCGCCGTCGGGCAAGTCGGTCACGTT
CACGGGCGTGCCCACGGGCGGATGGTTTGGCGAAGGCGCGGTGCTCAAGCACGAGATCCGCAAGTACGACGTCATGGCGC
TGCGCCGATCACGTATCGCCTTCATTCCCATCGAGACTTTTCAGTGGTTGCTGGATACCAGCCTGCCGTTCACGCGATTT
CTGCTGATGCAGCTCAATGACCGGCTTGGCCAGTTCATCGCGGCGGTCGAATACGAACGGCTGCTCGACATCGATTCACG
CGTGGCACGCGCCGTGTCGTCGCTGTTCAATGAGAGCCTCTATCCCGGCATTGGCACCACGCTCGAAATCTCGCAGGAGG
AGATCGGACTGCTCGCAGGCATCTCGCGTCAGCGCGCGAACCAGGCCCTCAAGGTGCTGGAACAACAGGGGCTGGTGCGT
GTGGATTATGGTGTGATCGAAGCACTCGATCTGGAGGGACTGCGGCAGTATGGGGAATGA

Upstream 100 bases:

>100_bases
GGTATCAAGCCCCCAGACCGGTCGTTATACTGGGCACGTCACATGCGGCGCTGCCGCACTGCATCATGCCTGCCTTGCCT
GTTTGTGCAATCGCACCTGG

Downstream 100 bases:

>100_bases
CGATCAGCCAGCGCTGCGCAGCCATTTCCGGTAGGCCTTTCGCCACCTTCGGCCCCTCCTCGCCGTGGCGGAAGGGGCCG
GATCAGCGCGCAACGCGCGC

Product: CRP family transcriptional regulator

Products: NA

Alternate protein names: cAMP receptor protein; cAMP regulatory protein [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MCWQRPVPRDRKIADAIPRGCHADDNSGLIPTIEMTATNNDFIDRCAWATNLSPEQRARVKRVTTVREYTQGEYVCHKGE
MAEHWLGVVEGVVKITTVSPSGKSVTFTGVPTGGWFGEGAVLKHEIRKYDVMALRRSRIAFIPIETFQWLLDTSLPFTRF
LLMQLNDRLGQFIAAVEYERLLDIDSRVARAVSSLFNESLYPGIGTTLEISQEEIGLLAGISRQRANQALKVLEQQGLVR
VDYGVIEALDLEGLRQYGE

Sequences:

>Translated_259_residues
MCWQRPVPRDRKIADAIPRGCHADDNSGLIPTIEMTATNNDFIDRCAWATNLSPEQRARVKRVTTVREYTQGEYVCHKGE
MAEHWLGVVEGVVKITTVSPSGKSVTFTGVPTGGWFGEGAVLKHEIRKYDVMALRRSRIAFIPIETFQWLLDTSLPFTRF
LLMQLNDRLGQFIAAVEYERLLDIDSRVARAVSSLFNESLYPGIGTTLEISQEEIGLLAGISRQRANQALKVLEQQGLVR
VDYGVIEALDLEGLRQYGE
>Mature_259_residues
MCWQRPVPRDRKIADAIPRGCHADDNSGLIPTIEMTATNNDFIDRCAWATNLSPEQRARVKRVTTVREYTQGEYVCHKGE
MAEHWLGVVEGVVKITTVSPSGKSVTFTGVPTGGWFGEGAVLKHEIRKYDVMALRRSRIAFIPIETFQWLLDTSLPFTRF
LLMQLNDRLGQFIAAVEYERLLDIDSRVARAVSSLFNESLYPGIGTTLEISQEEIGLLAGISRQRANQALKVLEQQGLVR
VDYGVIEALDLEGLRQYGE

Specific function: This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR018488
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 29115; Mature: 29115

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCWQRPVPRDRKIADAIPRGCHADDNSGLIPTIEMTATNNDFIDRCAWATNLSPEQRARV
CCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCHHHHHHH
KRVTTVREYTQGEYVCHKGEMAEHWLGVVEGVVKITTVSPSGKSVTFTGVPTGGWFGEGA
HHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHEEEEEECCCCCEEEEEECCCCCCCCCCH
VLKHEIRKYDVMALRRSRIAFIPIETFQWLLDTSLPFTRFLLMQLNDRLGQFIAAVEYER
HHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLDIDSRVARAVSSLFNESLYPGIGTTLEISQEEIGLLAGISRQRANQALKVLEQQGLVR
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VDYGVIEALDLEGLRQYGE
ECCHHHHHHCHHHHHHHCC
>Mature Secondary Structure
MCWQRPVPRDRKIADAIPRGCHADDNSGLIPTIEMTATNNDFIDRCAWATNLSPEQRARV
CCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCHHHHHHH
KRVTTVREYTQGEYVCHKGEMAEHWLGVVEGVVKITTVSPSGKSVTFTGVPTGGWFGEGA
HHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHEEEEEECCCCCEEEEEECCCCCCCCCCH
VLKHEIRKYDVMALRRSRIAFIPIETFQWLLDTSLPFTRFLLMQLNDRLGQFIAAVEYER
HHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLDIDSRVARAVSSLFNESLYPGIGTTLEISQEEIGLLAGISRQRANQALKVLEQQGLVR
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VDYGVIEALDLEGLRQYGE
ECCHHHHHHCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]