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The map label for this gene is dehH1 [H]

Identifier: 94309147

GI number: 94309147

Start: 210611

End: 211489

Strand: Direct

Name: dehH1 [H]

Synonym: Rmet_0202

Alternate gene names: 94309147

Gene position: 210611-211489 (Clockwise)

Preceding gene: 94309146

Following gene: 94309148

Centisome position: 5.36

GC content: 65.98

Gene sequence:

>879_bases
ATGTTCGAAGGATTCACGACCCAGCGCATTGATCACGACGGCGTGGCGATCCATGCGGTGGTCGGCGGAGAAGGTCCGCC
GCTGCTGCTGTTGCACGGCCATCCGCAGACCCATGTGATCTGGCACAAGGTGGCCGGTGAACTGGCCCGGCATTTCACGG
TGGTGGCCACCGATCTGCGTGGCTACGGCGATAGCGACAAGCCGGCGGGTCTGCCCGACCACAGCAACTACAGCAAGCGG
ACAATGGCGGCCGATCAGATGGCGGTGATGCGGGCACTCGGCTTCGAGCGTTTCCGCGTGCTCGCTCACGACCGCGGCGC
GCGCGTGGCGCACCGGCTGGCCGTCGATCATCCGCAGGCTGTGGAGAAGCTCGTGACGCTCGATATCGCCCCGACGCTGG
CGATGTACGCGCAGACCAACGAGGCGTTTGCCCGGGCCTACTATCACTGGTTCTTCCTGATCCGTCCCGCGCCGTTCCCG
GAGACGTTGATCGAGGCCGACCCTGAGCTTTACCTGCGCCAGACCATGGGTAGCCGCAGCGCCGGCCTGGCGCCATTCAC
CGACGAGGCGCTGGCCGAATACCTGCGCGGGCTGCGCCAGCCGGGCGCGGCGCATGGACTGTGCGAGGACTATCGCGCCA
GCGCGGGCATCGATCTCGATCACGACCGCGCCGATATCGAGGCTGGCCGCATGATCGAATGCGAGATGCTGGCGTTGTGG
GGAGCCGACGGGGCTGTCGGAAAGTGTTTTCAGCCACTTGAAGAATGGCGCAAGGTCGCCCGCCGTGTGACCGGTCACGC
ACTACCATGCGGGCACTACATCGCCGAGGAAATCCCGGAGCAACTGCTGGCGGAAGTGCTCCCGTTCCTGCGCGCCTGA

Upstream 100 bases:

>100_bases
TTCACAAGTCGGCACCACGCGGACAACCCCTGGCTACGCGACGTGGCCGCGACTACCATGGCACGGCTCGGCCGCATGGC
TGGCTGACGGAGGAGATACG

Downstream 100 bases:

>100_bases
GCGCGGCAACCTGTTGATTCCGCGATGTTTATCCTTCTCCCGCAGTCAGCCGGGAGAGGGATAATCGGCATCGGCGTGTG
ACTCGCGCCGATCGCGCCCG

Product: Haloacetate dehalogenase H-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MFEGFTTQRIDHDGVAIHAVVGGEGPPLLLLHGHPQTHVIWHKVAGELARHFTVVATDLRGYGDSDKPAGLPDHSNYSKR
TMAADQMAVMRALGFERFRVLAHDRGARVAHRLAVDHPQAVEKLVTLDIAPTLAMYAQTNEAFARAYYHWFFLIRPAPFP
ETLIEADPELYLRQTMGSRSAGLAPFTDEALAEYLRGLRQPGAAHGLCEDYRASAGIDLDHDRADIEAGRMIECEMLALW
GADGAVGKCFQPLEEWRKVARRVTGHALPCGHYIAEEIPEQLLAEVLPFLRA

Sequences:

>Translated_292_residues
MFEGFTTQRIDHDGVAIHAVVGGEGPPLLLLHGHPQTHVIWHKVAGELARHFTVVATDLRGYGDSDKPAGLPDHSNYSKR
TMAADQMAVMRALGFERFRVLAHDRGARVAHRLAVDHPQAVEKLVTLDIAPTLAMYAQTNEAFARAYYHWFFLIRPAPFP
ETLIEADPELYLRQTMGSRSAGLAPFTDEALAEYLRGLRQPGAAHGLCEDYRASAGIDLDHDRADIEAGRMIECEMLALW
GADGAVGKCFQPLEEWRKVARRVTGHALPCGHYIAEEIPEQLLAEVLPFLRA
>Mature_292_residues
MFEGFTTQRIDHDGVAIHAVVGGEGPPLLLLHGHPQTHVIWHKVAGELARHFTVVATDLRGYGDSDKPAGLPDHSNYSKR
TMAADQMAVMRALGFERFRVLAHDRGARVAHRLAVDHPQAVEKLVTLDIAPTLAMYAQTNEAFARAYYHWFFLIRPAPFP
ETLIEADPELYLRQTMGSRSAGLAPFTDEALAEYLRGLRQPGAAHGLCEDYRASAGIDLDHDRADIEAGRMIECEMLALW
GADGAVGKCFQPLEEWRKVARRVTGHALPCGHYIAEEIPEQLLAEVLPFLRA

Specific function: Unknown

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=297, Percent_Identity=27.9461279461279, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI13376164, Length=297, Percent_Identity=27.9461279461279, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI218777837, Length=247, Percent_Identity=29.5546558704453, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17554012, Length=301, Percent_Identity=26.2458471760797, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17562298, Length=238, Percent_Identity=25.6302521008403, Blast_Score=84, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.3 [H]

Molecular weight: Translated: 32389; Mature: 32389

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEGFTTQRIDHDGVAIHAVVGGEGPPLLLLHGHPQTHVIWHKVAGELARHFTVVATDLR
CCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHEEEHHC
GYGDSDKPAGLPDHSNYSKRTMAADQMAVMRALGFERFRVLAHDRGARVAHRLAVDHPQA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHH
VEKLVTLDIAPTLAMYAQTNEAFARAYYHWFFLIRPAPFPETLIEADPELYLRQTMGSRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHCCHHHHHHHHCCCCC
AGLAPFTDEALAEYLRGLRQPGAAHGLCEDYRASAGIDLDHDRADIEAGRMIECEMLALW
CCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEE
GADGAVGKCFQPLEEWRKVARRVTGHALPCGHYIAEEIPEQLLAEVLPFLRA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFEGFTTQRIDHDGVAIHAVVGGEGPPLLLLHGHPQTHVIWHKVAGELARHFTVVATDLR
CCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHEEEHHC
GYGDSDKPAGLPDHSNYSKRTMAADQMAVMRALGFERFRVLAHDRGARVAHRLAVDHPQA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHH
VEKLVTLDIAPTLAMYAQTNEAFARAYYHWFFLIRPAPFPETLIEADPELYLRQTMGSRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHCCHHHHHHHHCCCCC
AGLAPFTDEALAEYLRGLRQPGAAHGLCEDYRASAGIDLDHDRADIEAGRMIECEMLALW
CCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEE
GADGAVGKCFQPLEEWRKVARRVTGHALPCGHYIAEEIPEQLLAEVLPFLRA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1512562 [H]