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The map label for this gene is metX

Identifier: 94309088

GI number: 94309088

Start: 147516

End: 148688

Strand: Direct

Name: metX

Synonym: Rmet_0143

Alternate gene names: 94309088

Gene position: 147516-148688 (Clockwise)

Preceding gene: 94309087

Following gene: 94309089

Centisome position: 3.76

GC content: 64.88

Gene sequence:

>1173_bases
ATGACCGATGTCGCTCCTCCCGCTGGTGTGCTCGACGTGCCGACCGATTCCGTCGGTGTCGTTACGCCCCAGCGCATGCA
TTTTTCGGAGCCGCTGCAGCTCCGCAACGGCAGCCAGATCGCCGACTACGACCTGATGGTCGAAACCTACGGCACGCTGA
ACGCCGCGCGGACCAATGCCGTGCTGGTCTGTCACGCGCTCAACGCCTCGCACCACGTCGCCGGCATCGCCGCGGACAAT
CCGCGCGATATCGGCTGGTGGGACAACATGGTGGGCCCCGGCAAGCCGCTCGACACCAACCGCTTCTTCGTGATCGGCGT
GAACAACCTCGGCTCGTGCTTCGGATCGACCGGGCCGATGAGCACCAATCCGTCGACCGGGGCGCCGTATGGCGCGTTGT
TCCCGGTGGTGACGGTGGAAGACTGGGTCAACGCGCAGGCGCGCGTGGCCGACATATTCGGCATTCAACAGTTCGCCGCC
GTGATGGGCGGCAGCCTGGGCGGCATGCAGGCGCTGGCCTGGAGCCTGATGTATCCGGAGCGGCTGCGCCACTGCATCGT
GGTGGCTTCCACGCCGAAACTGTCCGCGCAGAACATCGCGTTCAACGAGGTCGCGCGCAGTTCCATCCTGTCGGACCCGG
ATTTCCACGGCGGCAACTACTACGCGCACAACGTCAAGCCGAAGCGCGGCCTGCGCGTGGCGCGGATGATCGGCCATATC
ACCTATCTGTCCGACGAGGACATGGCCGAGAAATTCGGCCGCTCGCTGAAGGCCGAGGACATCCGCTTCTCGTTTGACGT
CGAGTTCCAGGTGGAAAGCTACCTGCGTTACCAGGGCGACAAATTCGCCGAGTACTTCGACGCGAATACCTACCTGCTGA
TCACGCGCGCGCTCGACTACTTCGATCCGGCGCTGGCGCACGGTGGCGACCTGACGCGCGCCATGGCGCAGACGCAGGCC
GGCTTCCTGGTCGTCAGTTTCACCACGGACTGGCGCTTTGCGCCGAACCGCAGCCGCGAGATCGTCAAGGCGCTGCTCGA
CAACAAGCGACCGGTGTCGTACGCGGAGATCGACGCTCCGCACGGCCACGATGCCTTCCTGCTCGACGACGCCCGCTATC
ACAACCTGATGCGCGCCTACTACGACCGCATCGCAGAGGAGATCGGCGCATGA

Upstream 100 bases:

>100_bases
CCGGCACGCGGGACACCGCGAACGCCCGACTTGGCTGCGAAGCATCACACGCACTGCCAGTCGGGTTTTTTTATGCCTGC
CTCACTCGCGGGCCCCGCTC

Downstream 100 bases:

>100_bases
ACGCGGCTTCCAATCCGAATATCCTCGCGCTGCGTCCGGACTTCCGCGCTATCGCGCGCTGGATCGAACCGAACTCCACC
GTGCTCGACGCCGGCTGCGG

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MTDVAPPAGVLDVPTDSVGVVTPQRMHFSEPLQLRNGSQIADYDLMVETYGTLNAARTNAVLVCHALNASHHVAGIAADN
PRDIGWWDNMVGPGKPLDTNRFFVIGVNNLGSCFGSTGPMSTNPSTGAPYGALFPVVTVEDWVNAQARVADIFGIQQFAA
VMGGSLGGMQALAWSLMYPERLRHCIVVASTPKLSAQNIAFNEVARSSILSDPDFHGGNYYAHNVKPKRGLRVARMIGHI
TYLSDEDMAEKFGRSLKAEDIRFSFDVEFQVESYLRYQGDKFAEYFDANTYLLITRALDYFDPALAHGGDLTRAMAQTQA
GFLVVSFTTDWRFAPNRSREIVKALLDNKRPVSYAEIDAPHGHDAFLLDDARYHNLMRAYYDRIAEEIGA

Sequences:

>Translated_390_residues
MTDVAPPAGVLDVPTDSVGVVTPQRMHFSEPLQLRNGSQIADYDLMVETYGTLNAARTNAVLVCHALNASHHVAGIAADN
PRDIGWWDNMVGPGKPLDTNRFFVIGVNNLGSCFGSTGPMSTNPSTGAPYGALFPVVTVEDWVNAQARVADIFGIQQFAA
VMGGSLGGMQALAWSLMYPERLRHCIVVASTPKLSAQNIAFNEVARSSILSDPDFHGGNYYAHNVKPKRGLRVARMIGHI
TYLSDEDMAEKFGRSLKAEDIRFSFDVEFQVESYLRYQGDKFAEYFDANTYLLITRALDYFDPALAHGGDLTRAMAQTQA
GFLVVSFTTDWRFAPNRSREIVKALLDNKRPVSYAEIDAPHGHDAFLLDDARYHNLMRAYYDRIAEEIGA
>Mature_389_residues
TDVAPPAGVLDVPTDSVGVVTPQRMHFSEPLQLRNGSQIADYDLMVETYGTLNAARTNAVLVCHALNASHHVAGIAADNP
RDIGWWDNMVGPGKPLDTNRFFVIGVNNLGSCFGSTGPMSTNPSTGAPYGALFPVVTVEDWVNAQARVADIFGIQQFAAV
MGGSLGGMQALAWSLMYPERLRHCIVVASTPKLSAQNIAFNEVARSSILSDPDFHGGNYYAHNVKPKRGLRVARMIGHIT
YLSDEDMAEKFGRSLKAEDIRFSFDVEFQVESYLRYQGDKFAEYFDANTYLLITRALDYFDPALAHGGDLTRAMAQTQAG
FLVVSFTTDWRFAPNRSREIVKALLDNKRPVSYAEIDAPHGHDAFLLDDARYHNLMRAYYDRIAEEIGA

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=238, Percent_Identity=36.9747899159664, Blast_Score=157, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_RALME (Q1LS47)

Other databases:

- EMBL:   CP000352
- RefSeq:   YP_582298.1
- STRING:   Q1LS47
- GeneID:   4036927
- GenomeReviews:   CP000352_GR
- KEGG:   rme:Rmet_0143
- eggNOG:   COG2021
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- PhylomeDB:   Q1LS47
- ProtClustDB:   PRK00175
- BioCyc:   RMET266264:RMET_0143-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 43010; Mature: 42879

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: ACT_SITE 165-165 ACT_SITE 363-363

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDVAPPAGVLDVPTDSVGVVTPQRMHFSEPLQLRNGSQIADYDLMVETYGTLNAARTNA
CCCCCCCCCEEECCCCCCCCCCCHHHCCCCCHHHCCCCCCCCCEEEEEECCCCCCCCCCE
VLVCHALNASHHVAGIAADNPRDIGWWDNMVGPGKPLDTNRFFVIGVNNLGSCFGSTGPM
EEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCC
STNPSTGAPYGALFPVVTVEDWVNAQARVADIFGIQQFAAVMGGSLGGMQALAWSLMYPE
CCCCCCCCCCHHHEEEEEEHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHH
RLRHCIVVASTPKLSAQNIAFNEVARSSILSDPDFHGGNYYAHNVKPKRGLRVARMIGHI
HCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHH
TYLSDEDMAEKFGRSLKAEDIRFSFDVEFQVESYLRYQGDKFAEYFDANTYLLITRALDY
EECCCHHHHHHHCCCCCCCCEEEEEEEEEEHHHHHHHCCCHHHHHHCCCCEEEEEHHHHH
FDPALAHGGDLTRAMAQTQAGFLVVSFTTDWRFAPNRSREIVKALLDNKRPVSYAEIDAP
HCHHHHCCCHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEECCCC
HGHDAFLLDDARYHNLMRAYYDRIAEEIGA
CCCCEEEECCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDVAPPAGVLDVPTDSVGVVTPQRMHFSEPLQLRNGSQIADYDLMVETYGTLNAARTNA
CCCCCCCCEEECCCCCCCCCCCHHHCCCCCHHHCCCCCCCCCEEEEEECCCCCCCCCCE
VLVCHALNASHHVAGIAADNPRDIGWWDNMVGPGKPLDTNRFFVIGVNNLGSCFGSTGPM
EEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCC
STNPSTGAPYGALFPVVTVEDWVNAQARVADIFGIQQFAAVMGGSLGGMQALAWSLMYPE
CCCCCCCCCCHHHEEEEEEHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHH
RLRHCIVVASTPKLSAQNIAFNEVARSSILSDPDFHGGNYYAHNVKPKRGLRVARMIGHI
HCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHH
TYLSDEDMAEKFGRSLKAEDIRFSFDVEFQVESYLRYQGDKFAEYFDANTYLLITRALDY
EECCCHHHHHHHCCCCCCCCEEEEEEEEEEHHHHHHHCCCHHHHHHCCCCEEEEEHHHHH
FDPALAHGGDLTRAMAQTQAGFLVVSFTTDWRFAPNRSREIVKALLDNKRPVSYAEIDAP
HCHHHHCCCHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEECCCC
HGHDAFLLDDARYHNLMRAYYDRIAEEIGA
CCCCEEEECCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA