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The map label for this gene is ttk [H]

Identifier: 94309087

GI number: 94309087

Start: 146595

End: 147245

Strand: Direct

Name: ttk [H]

Synonym: Rmet_0142

Alternate gene names: 94309087

Gene position: 146595-147245 (Clockwise)

Preceding gene: 94309086

Following gene: 94309088

Centisome position: 3.73

GC content: 65.13

Gene sequence:

>651_bases
ATGACTCAAACCATTTCAAGCCAGGCAGAGGCGGACACGCCCGCTGGCCACTCGCCGGAAGCGGCGCCCGCGCGCAAGCG
TCCGCGCCCGGGTGAACGCCGTATCCAGATCCTCCAGACGCTGGCAGGGATGCTCGAACACCCGCGCGGGGAAAAGATCA
CCACCGCGGCGCTGGCTGCGAAGCTCTCGGTATCCGAGGCCGCGCTGTACCGGCACTTTGCCAGCAAGGCGCAGATGTTC
GAAGGCCTGATCGGCTTCATCGAGCAGACCGTCTTCGGCCTGATCAACCAGATCACCACGCAGGAAGAGCATGGGCTGCG
CCAGGCGCAGGCGATCGTGCGCATGCTGCTGTCGTTCGCCGAGAAGAACCCCGGCATGACGCGTGTGCTGACTGGCGAGG
CGCTCGTCGGCGAACACGAGCGCTTGCAGGAGCGCATCAACCAGATGATCGACCGTATCGAGGCGTCGCTGCGTCAGTGT
CTGAAGGTGGCCGTCAGTCAGGCGGCGTTTCCGCCCGATGCCGATATTCCGTTGCGCGTGGCGCTGATCACGGCGGCCGT
GCAGGGGCACTGGCATCGCTTCGTGAAGAGCGGTTTCCGCAAGGCGCCGACCGAGAATATCGATGCGCAACTGCGCATCC
TGCTGGGCTGA

Upstream 100 bases:

>100_bases
TGCCGCGTATGCGGGCACGCGTGACGAATCGGCCCGGCTATGTGGACATAAAAGTACAATCGATGCATCAACTCCTACGA
CGAATGTGGAGAACCGGGTC

Downstream 100 bases:

>100_bases
TCCGAACAGGAGCAGGCACAAAAAACGGTTTGCACTATAATGTGCGGGTCGCGCCGATTTGATGACTGGCTTGCGGGCGC
GCGGCGATGGGAAGGGAAGT

Product: division inhibitor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MTQTISSQAEADTPAGHSPEAAPARKRPRPGERRIQILQTLAGMLEHPRGEKITTAALAAKLSVSEAALYRHFASKAQMF
EGLIGFIEQTVFGLINQITTQEEHGLRQAQAIVRMLLSFAEKNPGMTRVLTGEALVGEHERLQERINQMIDRIEASLRQC
LKVAVSQAAFPPDADIPLRVALITAAVQGHWHRFVKSGFRKAPTENIDAQLRILLG

Sequences:

>Translated_216_residues
MTQTISSQAEADTPAGHSPEAAPARKRPRPGERRIQILQTLAGMLEHPRGEKITTAALAAKLSVSEAALYRHFASKAQMF
EGLIGFIEQTVFGLINQITTQEEHGLRQAQAIVRMLLSFAEKNPGMTRVLTGEALVGEHERLQERINQMIDRIEASLRQC
LKVAVSQAAFPPDADIPLRVALITAAVQGHWHRFVKSGFRKAPTENIDAQLRILLG
>Mature_215_residues
TQTISSQAEADTPAGHSPEAAPARKRPRPGERRIQILQTLAGMLEHPRGEKITTAALAAKLSVSEAALYRHFASKAQMFE
GLIGFIEQTVFGLINQITTQEEHGLRQAQAIVRMLLSFAEKNPGMTRVLTGEALVGEHERLQERINQMIDRIEASLRQCL
KVAVSQAAFPPDADIPLRVALITAAVQGHWHRFVKSGFRKAPTENIDAQLRILLG

Specific function: Required for nucleoid occlusion (NO) phenomenon, which cooperates in the proper positioning of the ftsZ/septal ring at midcell during cell division [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm, nucleoid [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082302, Length=188, Percent_Identity=47.3404255319149, Blast_Score=147, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 23801; Mature: 23670

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTISSQAEADTPAGHSPEAAPARKRPRPGERRIQILQTLAGMLEHPRGEKITTAALAA
CCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
KLSVSEAALYRHFASKAQMFEGLIGFIEQTVFGLINQITTQEEHGLRQAQAIVRMLLSFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKNPGMTRVLTGEALVGEHERLQERINQMIDRIEASLRQCLKVAVSQAAFPPDADIPLRV
HCCCCCEEEECCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
ALITAAVQGHWHRFVKSGFRKAPTENIDAQLRILLG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECC
>Mature Secondary Structure 
TQTISSQAEADTPAGHSPEAAPARKRPRPGERRIQILQTLAGMLEHPRGEKITTAALAA
CCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
KLSVSEAALYRHFASKAQMFEGLIGFIEQTVFGLINQITTQEEHGLRQAQAIVRMLLSFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKNPGMTRVLTGEALVGEHERLQERINQMIDRIEASLRQCLKVAVSQAAFPPDADIPLRV
HCCCCCEEEECCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
ALITAAVQGHWHRFVKSGFRKAPTENIDAQLRILLG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA