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The map label for this gene is xerC [H]

Identifier: 94309002

GI number: 94309002

Start: 65517

End: 66626

Strand: Direct

Name: xerC [H]

Synonym: Rmet_0057

Alternate gene names: 94309002

Gene position: 65517-66626 (Clockwise)

Preceding gene: 94309001

Following gene: 94309004

Centisome position: 1.67

GC content: 67.21

Gene sequence:

>1110_bases
ATGCGCACGCGCCAGCCGGCACGCAACAGGGCCCATGCGGTCGATGAGGCTGATGAGGCGTCGGCCGAGAAGCCGGCCCC
AGACCCGCTGGTGGTGCGCTATCTCGACTGGCTGGCGACGAGCCGAAAGCTCGCCGCGCACACGCTGACCAGCTACGGGC
ACGATCTGTCCGTGTTGCAGTCGCAAGCCATTCGCCTGGCGCCCGGCGTGGCGTTGCTGGCGCTGGAGACCCGTCACATT
CGTTCGTTTGCGGCGCGGCTGCATGGCAATGGCCTGTCGGCCCGCACCATCGCACGCACGCTGTCGGCGTGGCGCGGCTT
CTATCTCTGGGCGGCGCGGCATGGTCACGGCGTACAGTCCAATCCCGTCGACGGCGTGCGCGCGCCCAAGCGTGGCAGGC
CGCTGCCCAAGGCGCTCTCGGTCGAACATGCGGTGGCGCTGGTCGCCCATCGCCAGGACGACACCAACGAATCGCTACGT
GATCAGGCTGTCTTTGAGCTGTTCTATTCGAGCGGCCTGCGGCTGTCAGAGCTGATCCAGCTAGACGTCCGCTATACGGA
GGACGGCGACTATCGCTCGTCCGGCTGGCTCGATCTCGATGGCGCCGAAGTGACCGTGCTCGGCAAGGGTTCGCGCCGGC
GCACCGTGCCGGTGGGCAGCAAGGCGATCCAGGCGCTGAAAGCCTGGATTCATGTGCGCGAGATGATGCTGCGGCCCGGC
GCGCTGCCCGAGGATGCCCACGCGCTGTTTCTTGGCACGCGCGGCCGGCGGTTGCCGATCAGCACGGTGCAGCAGCGCAT
CAAACGCCAGGCGCTGGCCGCGGGCGTGCCCAGCGATGTCCATCCGCACATGCTGCGCCACTCGTTCGCCACGCATATGC
TGCAGTCGTCCGGTGACCTGCGGGCGGTGCAGGAAATGCTGGGCCACGCCAGCATCTCCACCACGCAGATCTACACTTCG
CTCGATTTCCAGCACCTGGCCAAGGTCTACGATCAGGCCCACCCGCGCGCCGGTCGGGCAAGCAAGTCGCCGAAGGCATC
CAGCGTGAAACCCAGCAAGCCGGACGAATCGGACGAGTTGGCCGAGCCGGACGATTCAGGCGAAGACTAG

Upstream 100 bases:

>100_bases
TTCCATGAGGGTATGGGCACTGCCTATCTGGCCCAGATCGGCGAAGTCGCCGGCGCGGCGCTGAATCGCCTGCGCGACTA
AGCGGGGCAAACACTCCTCC

Downstream 100 bases:

>100_bases
TTCCACTGCGAGAGGATGTTGCGGAATCGCTCCATCTCGGGCAGCAGCCAGTGCCGGAAGGCCTGGACTTTGGGTGTCTC
CAGACTGGCGTGCGTGCAGA

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MRTRQPARNRAHAVDEADEASAEKPAPDPLVVRYLDWLATSRKLAAHTLTSYGHDLSVLQSQAIRLAPGVALLALETRHI
RSFAARLHGNGLSARTIARTLSAWRGFYLWAARHGHGVQSNPVDGVRAPKRGRPLPKALSVEHAVALVAHRQDDTNESLR
DQAVFELFYSSGLRLSELIQLDVRYTEDGDYRSSGWLDLDGAEVTVLGKGSRRRTVPVGSKAIQALKAWIHVREMMLRPG
ALPEDAHALFLGTRGRRLPISTVQQRIKRQALAAGVPSDVHPHMLRHSFATHMLQSSGDLRAVQEMLGHASISTTQIYTS
LDFQHLAKVYDQAHPRAGRASKSPKASSVKPSKPDESDELAEPDDSGED

Sequences:

>Translated_369_residues
MRTRQPARNRAHAVDEADEASAEKPAPDPLVVRYLDWLATSRKLAAHTLTSYGHDLSVLQSQAIRLAPGVALLALETRHI
RSFAARLHGNGLSARTIARTLSAWRGFYLWAARHGHGVQSNPVDGVRAPKRGRPLPKALSVEHAVALVAHRQDDTNESLR
DQAVFELFYSSGLRLSELIQLDVRYTEDGDYRSSGWLDLDGAEVTVLGKGSRRRTVPVGSKAIQALKAWIHVREMMLRPG
ALPEDAHALFLGTRGRRLPISTVQQRIKRQALAAGVPSDVHPHMLRHSFATHMLQSSGDLRAVQEMLGHASISTTQIYTS
LDFQHLAKVYDQAHPRAGRASKSPKASSVKPSKPDESDELAEPDDSGED
>Mature_369_residues
MRTRQPARNRAHAVDEADEASAEKPAPDPLVVRYLDWLATSRKLAAHTLTSYGHDLSVLQSQAIRLAPGVALLALETRHI
RSFAARLHGNGLSARTIARTLSAWRGFYLWAARHGHGVQSNPVDGVRAPKRGRPLPKALSVEHAVALVAHRQDDTNESLR
DQAVFELFYSSGLRLSELIQLDVRYTEDGDYRSSGWLDLDGAEVTVLGKGSRRRTVPVGSKAIQALKAWIHVREMMLRPG
ALPEDAHALFLGTRGRRLPISTVQQRIKRQALAAGVPSDVHPHMLRHSFATHMLQSSGDLRAVQEMLGHASISTTQIYTS
LDFQHLAKVYDQAHPRAGRASKSPKASSVKPSKPDESDELAEPDDSGED

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=315, Percent_Identity=42.5396825396825, Blast_Score=228, Evalue=6e-61,
Organism=Escherichia coli, GI1789261, Length=309, Percent_Identity=33.6569579288026, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1790768, Length=174, Percent_Identity=29.3103448275862, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790767, Length=179, Percent_Identity=29.608938547486, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 40617; Mature: 40617

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTRQPARNRAHAVDEADEASAEKPAPDPLVVRYLDWLATSRKLAAHTLTSYGHDLSVLQ
CCCCCCCHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SQAIRLAPGVALLALETRHIRSFAARLHGNGLSARTIARTLSAWRGFYLWAARHGHGVQS
HHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCC
NPVDGVRAPKRGRPLPKALSVEHAVALVAHRQDDTNESLRDQAVFELFYSSGLRLSELIQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHE
LDVRYTEDGDYRSSGWLDLDGAEVTVLGKGSRRRTVPVGSKAIQALKAWIHVREMMLRPG
EHEEECCCCCCCCCCCEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
ALPEDAHALFLGTRGRRLPISTVQQRIKRQALAAGVPSDVHPHMLRHSFATHMLQSSGDL
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCH
RAVQEMLGHASISTTQIYTSLDFQHLAKVYDQAHPRAGRASKSPKASSVKPSKPDESDEL
HHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AEPDDSGED
CCCCCCCCC
>Mature Secondary Structure
MRTRQPARNRAHAVDEADEASAEKPAPDPLVVRYLDWLATSRKLAAHTLTSYGHDLSVLQ
CCCCCCCHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
SQAIRLAPGVALLALETRHIRSFAARLHGNGLSARTIARTLSAWRGFYLWAARHGHGVQS
HHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEEEECCCCCCCC
NPVDGVRAPKRGRPLPKALSVEHAVALVAHRQDDTNESLRDQAVFELFYSSGLRLSELIQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHE
LDVRYTEDGDYRSSGWLDLDGAEVTVLGKGSRRRTVPVGSKAIQALKAWIHVREMMLRPG
EHEEECCCCCCCCCCCEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
ALPEDAHALFLGTRGRRLPISTVQQRIKRQALAAGVPSDVHPHMLRHSFATHMLQSSGDL
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCH
RAVQEMLGHASISTTQIYTSLDFQHLAKVYDQAHPRAGRASKSPKASSVKPSKPDESDEL
HHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AEPDDSGED
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA