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The map label for this gene is avtA [H]

Identifier: 93007264

GI number: 93007264

Start: 3015244

End: 3016578

Strand: Direct

Name: avtA [H]

Synonym: Pcryo_2440

Alternate gene names: 93007264

Gene position: 3015244-3016578 (Clockwise)

Preceding gene: 93007260

Following gene: 93007268

Centisome position: 98.54

GC content: 45.99

Gene sequence:

>1335_bases
ATGAAATTCTCAAAGTTCGGTCAAAAATTTACCCAGCCCACTGGCATCTCACAATTAATGGACGATCTAGGCGACGCGCT
AAAAAGCGATCAGCCTGTAAATATGCTGGGCGGTGGTAACCCTGCCAAAATTGATGCCGTCAATGAGTTATTTTTGGAAA
CGTATAAAGCGCTTGGTAATGACAATGATGCGGGTGAGGCCAATAGTAGCGCTATCATCAGCATGGCGAATTACTCTAAT
CCACAAGGTGATTCGGCCTTTATCGATGCCTTGGTTGGCTTCTTTAACCGTCATTATGATTGGAATCTGACCTCAGAAAA
TATCGCGCTGACCAATGGCTCACAGAATGCATTTTTCTATCTATTCAACCTATTCGGTGGCGCTTTCATTGATGAACAGA
GCCAGTCTTTAGACAAATCCATTCTACTGCCATTGACCCCTGAGTATATCGGCTATAGCGACGTGCATGTCGAAGGTCAG
CATTTCGCAGCGGTACTACCGCATATCGATGAAGTGACGCATGATGGCGAGGAAGGTTTCTTTAAATATCGCGTCGACTT
TGAAGCGTTAGAGAACTTGCCAGCATTAAAGGAAGGTCGCATCGGCGCGATTTGCTGCTCACGCCCGACCAATCCTACTG
GCAACGTGCTGACCGATGACGAAATGGCGCATTTGGCCGAGATTGCCAAACAGTATGACATACCGCTGATTATCGATAAC
GCCTACGGTATGCCCTTCCCTAACATCATCTACTCTGACGCGCATCTGAATTGGGATAACAATACGATTCTATGCTTTAG
CCTGTCTAAAATTGGCCTGCCCGGTATGCGTACGGGGATTATCGTGGCCGATGCGAAAGTGATCGAAGCCGTCAGCGCGA
TGAATGCGGTGGTGAATCTAGCACCGACAAGATTTGGTGCAGCGATTGCCACGCCATTGGTAGAAAACGATCGTATCAAG
CAATTAGCTGATAATGAGATTAAGCCGTTTTATCAAAAGCAGGTCACCCTTGCCGTGAAGCTGTTAAAAGAAGCATTGGG
CGATTATCCATTGATGATTCATAAGCCTGAAGGCGCGATTTTCCTATGGTTGTGGTTTAAAGACTTGCCGATTAGTACGC
TTGAGCTGTACGAGCGCCTAAAAGAAAAAGGTACGCTTATTGTACCAAGCGAGTACTTCTTCCCCGGTGTCGATGTCAGC
GATTATCAGCACGCACACGAGTGTATTCGTATGAGTATCGCTGCTGATGAGCAAACACTGACTGATGGTATTAGAGCAAT
TGGTGAAGTAGTACGTGAGTTGTATGATGAAGCTAAAAATAACAAAGCATCATAA

Upstream 100 bases:

>100_bases
TAGACTTAGCTCTCCTCACCCCAGTCATTTGCTATACTAGCCTAACTTTTATCAATCAAATTCCTTCTTACAAAATCCTC
CAAAACAGTATGGTAGTCTT

Downstream 100 bases:

>100_bases
CTTCAATGATAAAAATAGTTCAATAGTAAAAAACGGACTTATGAATAGTCCGTTTTTTTCTGCCTTTTAATCATAGGTTT
GACTGTACTGATTGACTGAA

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MKFSKFGQKFTQPTGISQLMDDLGDALKSDQPVNMLGGGNPAKIDAVNELFLETYKALGNDNDAGEANSSAIISMANYSN
PQGDSAFIDALVGFFNRHYDWNLTSENIALTNGSQNAFFYLFNLFGGAFIDEQSQSLDKSILLPLTPEYIGYSDVHVEGQ
HFAAVLPHIDEVTHDGEEGFFKYRVDFEALENLPALKEGRIGAICCSRPTNPTGNVLTDDEMAHLAEIAKQYDIPLIIDN
AYGMPFPNIIYSDAHLNWDNNTILCFSLSKIGLPGMRTGIIVADAKVIEAVSAMNAVVNLAPTRFGAAIATPLVENDRIK
QLADNEIKPFYQKQVTLAVKLLKEALGDYPLMIHKPEGAIFLWLWFKDLPISTLELYERLKEKGTLIVPSEYFFPGVDVS
DYQHAHECIRMSIAADEQTLTDGIRAIGEVVRELYDEAKNNKAS

Sequences:

>Translated_444_residues
MKFSKFGQKFTQPTGISQLMDDLGDALKSDQPVNMLGGGNPAKIDAVNELFLETYKALGNDNDAGEANSSAIISMANYSN
PQGDSAFIDALVGFFNRHYDWNLTSENIALTNGSQNAFFYLFNLFGGAFIDEQSQSLDKSILLPLTPEYIGYSDVHVEGQ
HFAAVLPHIDEVTHDGEEGFFKYRVDFEALENLPALKEGRIGAICCSRPTNPTGNVLTDDEMAHLAEIAKQYDIPLIIDN
AYGMPFPNIIYSDAHLNWDNNTILCFSLSKIGLPGMRTGIIVADAKVIEAVSAMNAVVNLAPTRFGAAIATPLVENDRIK
QLADNEIKPFYQKQVTLAVKLLKEALGDYPLMIHKPEGAIFLWLWFKDLPISTLELYERLKEKGTLIVPSEYFFPGVDVS
DYQHAHECIRMSIAADEQTLTDGIRAIGEVVRELYDEAKNNKAS
>Mature_444_residues
MKFSKFGQKFTQPTGISQLMDDLGDALKSDQPVNMLGGGNPAKIDAVNELFLETYKALGNDNDAGEANSSAIISMANYSN
PQGDSAFIDALVGFFNRHYDWNLTSENIALTNGSQNAFFYLFNLFGGAFIDEQSQSLDKSILLPLTPEYIGYSDVHVEGQ
HFAAVLPHIDEVTHDGEEGFFKYRVDFEALENLPALKEGRIGAICCSRPTNPTGNVLTDDEMAHLAEIAKQYDIPLIIDN
AYGMPFPNIIYSDAHLNWDNNTILCFSLSKIGLPGMRTGIIVADAKVIEAVSAMNAVVNLAPTRFGAAIATPLVENDRIK
QLADNEIKPFYQKQVTLAVKLLKEALGDYPLMIHKPEGAIFLWLWFKDLPISTLELYERLKEKGTLIVPSEYFFPGVDVS
DYQHAHECIRMSIAADEQTLTDGIRAIGEVVRELYDEAKNNKAS

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=438, Percent_Identity=44.5205479452055, Blast_Score=387, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 49121; Mature: 49121

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSKFGQKFTQPTGISQLMDDLGDALKSDQPVNMLGGGNPAKIDAVNELFLETYKALGN
CCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCC
DNDAGEANSSAIISMANYSNPQGDSAFIDALVGFFNRHYDWNLTSENIALTNGSQNAFFY
CCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHEE
LFNLFGGAFIDEQSQSLDKSILLPLTPEYIGYSDVHVEGQHFAAVLPHIDEVTHDGEEGF
HHHHHCCCCCCCHHHHCCCEEECCCCHHHCCCCEEEECCHHHHHHHHHHHHHCCCCCCCE
FKYRVDFEALENLPALKEGRIGAICCSRPTNPTGNVLTDDEMAHLAEIAKQYDIPLIIDN
EEEEEEHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEC
AYGMPFPNIIYSDAHLNWDNNTILCFSLSKIGLPGMRTGIIVADAKVIEAVSAMNAVVNL
CCCCCCCCEEEECCEECCCCCEEEEEEEHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHH
APTRFGAAIATPLVENDRIKQLADNEIKPFYQKQVTLAVKLLKEALGDYPLMIHKPEGAI
CCHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCE
FLWLWFKDLPISTLELYERLKEKGTLIVPSEYFFPGVDVSDYQHAHECIRMSIAADEQTL
EEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
TDGIRAIGEVVRELYDEAKNNKAS
HHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKFSKFGQKFTQPTGISQLMDDLGDALKSDQPVNMLGGGNPAKIDAVNELFLETYKALGN
CCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCC
DNDAGEANSSAIISMANYSNPQGDSAFIDALVGFFNRHYDWNLTSENIALTNGSQNAFFY
CCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHEE
LFNLFGGAFIDEQSQSLDKSILLPLTPEYIGYSDVHVEGQHFAAVLPHIDEVTHDGEEGF
HHHHHCCCCCCCHHHHCCCEEECCCCHHHCCCCEEEECCHHHHHHHHHHHHHCCCCCCCE
FKYRVDFEALENLPALKEGRIGAICCSRPTNPTGNVLTDDEMAHLAEIAKQYDIPLIIDN
EEEEEEHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEC
AYGMPFPNIIYSDAHLNWDNNTILCFSLSKIGLPGMRTGIIVADAKVIEAVSAMNAVVNL
CCCCCCCCEEEECCEECCCCCEEEEEEEHHCCCCCCCCCEEEECHHHHHHHHHHHHHHHH
APTRFGAAIATPLVENDRIKQLADNEIKPFYQKQVTLAVKLLKEALGDYPLMIHKPEGAI
CCHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCE
FLWLWFKDLPISTLELYERLKEKGTLIVPSEYFFPGVDVSDYQHAHECIRMSIAADEQTL
EEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
TDGIRAIGEVVRELYDEAKNNKAS
HHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]