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The map label for this gene is thrB [H]

Identifier: 93007214

GI number: 93007214

Start: 2938664

End: 2939833

Strand: Reverse

Name: thrB [H]

Synonym: Pcryo_2390

Alternate gene names: 93007214

Gene position: 2939833-2938664 (Counterclockwise)

Preceding gene: 93007222

Following gene: 93007213

Centisome position: 96.08

GC content: 42.39

Gene sequence:

>1170_bases
ATGTCCGTCTATACCCAGTTAACCGATGACCAATTTGCTACCTTTTGCCAACGTTTTGGCGTATCGTTCGCCCGTGCCAT
TCCGATTACCCAAGGTATCAAAAACTCTAACTGGTTTATTCAGACGACTGACGATGTAGATGGCGCACATTCTTATGTGT
TTACCTTGTTTGAAGAGCGTCCACCAGAAGACATCGAAAAAATGGCGGTTATCTTAAACCAATTAGATGGTAAATTGCCG
GTAGCGGCGCCATTATCATTGGTTGATAGCGCAGAAAAATGTTATGTCATACGTTATGACAACAAAGCTATTACGCTAGT
GCCATGTTTGGCAGGCTCGCATCCACAGCAGACGACGCAAGCGATGTGTCATGAAATTGGCGCGTCTTTGGCAGTATTGC
ATGAAACGCTACAACAGCTACAGCCTGCGGAAGAATATGGCGTGCCTTTATATCCATGGAGCGAGGTACGCGACCGTGAA
AAGCAGTTTATGCCAGCTGATGAAGCCAAGCTGATGAGTGATATTTGGCAATCTTATACGGACTTGCCACTTGCCACTTT
GCCAAAAGGCTTATGTCATTTAGACATGTTTGCTGATAATACTTTATGGAACTTATCTTTAAATAACAGTCAAAAAGGTG
AAGCGCATCTGACTGGGTTATTAGATTTCACCGAAGTCAGCGTTGAACATTATGTGATGGATATTGCCATTACGATTAAT
GATTTTTGTACCACATGGGGTATGGCTGAACAAGGCGAGTCGGTGAATTTTGACCGCAGTAAAATGGCGGCTTTTTTGCA
AGGCTATGAGTCGAAACGCATGCTCGGTGAAGATGAAAAGCGTGCACTACCAGTGATGCTCGCAAAAGCTGCGGTGATTT
TTTGGCTATTACGTCTCAACGTCATTCATTATAACCGTACCGAAGGTCGTACCGGTGATAACATCATGGTCAAAAACCCT
GACTTAATGAAGCGTCTAGCCGCTTATCATTGGTCACATGTTGAAAAAGCACAAAATACGGTATTTGTACTGTTAGCTAT
TAATAATAAGATCGAAAAGCCGATAGCTGGTGTGTTTAGCAGTATTACGCAAGCTGAGCAAACATGTGATAGTTTAGGTA
ATAGCAGCGATTTTATTATTAAAGAATATACGCTCGATCAATTAGTATAA

Upstream 100 bases:

>100_bases
AAGATTATTATGCTTTTAACCAAAGTTTGCTCATGCACGGTACAATCATTGTCATTACCGTATCTATTTACCTTCTTTTA
ATTGCCATAAGTGAGATGTC

Downstream 100 bases:

>100_bases
TTTTTTTAAGCATTCTTGTATCACAAATATAAAGGCGACCTCATGACCGATCAAGTTGATAACTGGCACAAACTGGCACG
CTACGATACCAATATCCAAG

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK [H]

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MSVYTQLTDDQFATFCQRFGVSFARAIPITQGIKNSNWFIQTTDDVDGAHSYVFTLFEERPPEDIEKMAVILNQLDGKLP
VAAPLSLVDSAEKCYVIRYDNKAITLVPCLAGSHPQQTTQAMCHEIGASLAVLHETLQQLQPAEEYGVPLYPWSEVRDRE
KQFMPADEAKLMSDIWQSYTDLPLATLPKGLCHLDMFADNTLWNLSLNNSQKGEAHLTGLLDFTEVSVEHYVMDIAITIN
DFCTTWGMAEQGESVNFDRSKMAAFLQGYESKRMLGEDEKRALPVMLAKAAVIFWLLRLNVIHYNRTEGRTGDNIMVKNP
DLMKRLAAYHWSHVEKAQNTVFVLLAINNKIEKPIAGVFSSITQAEQTCDSLGNSSDFIIKEYTLDQLV

Sequences:

>Translated_389_residues
MSVYTQLTDDQFATFCQRFGVSFARAIPITQGIKNSNWFIQTTDDVDGAHSYVFTLFEERPPEDIEKMAVILNQLDGKLP
VAAPLSLVDSAEKCYVIRYDNKAITLVPCLAGSHPQQTTQAMCHEIGASLAVLHETLQQLQPAEEYGVPLYPWSEVRDRE
KQFMPADEAKLMSDIWQSYTDLPLATLPKGLCHLDMFADNTLWNLSLNNSQKGEAHLTGLLDFTEVSVEHYVMDIAITIN
DFCTTWGMAEQGESVNFDRSKMAAFLQGYESKRMLGEDEKRALPVMLAKAAVIFWLLRLNVIHYNRTEGRTGDNIMVKNP
DLMKRLAAYHWSHVEKAQNTVFVLLAINNKIEKPIAGVFSSITQAEQTCDSLGNSSDFIIKEYTLDQLV
>Mature_388_residues
SVYTQLTDDQFATFCQRFGVSFARAIPITQGIKNSNWFIQTTDDVDGAHSYVFTLFEERPPEDIEKMAVILNQLDGKLPV
AAPLSLVDSAEKCYVIRYDNKAITLVPCLAGSHPQQTTQAMCHEIGASLAVLHETLQQLQPAEEYGVPLYPWSEVRDREK
QFMPADEAKLMSDIWQSYTDLPLATLPKGLCHLDMFADNTLWNLSLNNSQKGEAHLTGLLDFTEVSVEHYVMDIAITIND
FCTTWGMAEQGESVNFDRSKMAAFLQGYESKRMLGEDEKRALPVMLAKAAVIFWLLRLNVIHYNRTEGRTGDNIMVKNPD
LMKRLAAYHWSHVEKAQNTVFVLLAINNKIEKPIAGVFSSITQAEQTCDSLGNSSDFIIKEYTLDQLV

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: =2.7.1.39 [H]

Molecular weight: Translated: 43847; Mature: 43716

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVYTQLTDDQFATFCQRFGVSFARAIPITQGIKNSNWFIQTTDDVDGAHSYVFTLFEER
CCCCCCCCCHHHHHHHHHHCCHHHHHCCHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCC
PPEDIEKMAVILNQLDGKLPVAAPLSLVDSAEKCYVIRYDNKAITLVPCLAGSHPQQTTQ
CCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEEEECCCEEEEEEECCCCCCHHHHH
AMCHEIGASLAVLHETLQQLQPAEEYGVPLYPWSEVRDREKQFMPADEAKLMSDIWQSYT
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DLPLATLPKGLCHLDMFADNTLWNLSLNNSQKGEAHLTGLLDFTEVSVEHYVMDIAITIN
CCCHHHHCCHHHEEHEECCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHEEEEEEEEEH
DFCTTWGMAEQGESVNFDRSKMAAFLQGYESKRMLGEDEKRALPVMLAKAAVIFWLLRLN
HHHHHCCCCCCCCCCCCCHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VIHYNRTEGRTGDNIMVKNPDLMKRLAAYHWSHVEKAQNTVFVLLAINNKIEKPIAGVFS
HHEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHH
SITQAEQTCDSLGNSSDFIIKEYTLDQLV
HHHHHHHHHHHCCCCCCEEEEECCHHHCC
>Mature Secondary Structure 
SVYTQLTDDQFATFCQRFGVSFARAIPITQGIKNSNWFIQTTDDVDGAHSYVFTLFEER
CCCCCCCCHHHHHHHHHHCCHHHHHCCHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCC
PPEDIEKMAVILNQLDGKLPVAAPLSLVDSAEKCYVIRYDNKAITLVPCLAGSHPQQTTQ
CCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEEEECCCEEEEEEECCCCCCHHHHH
AMCHEIGASLAVLHETLQQLQPAEEYGVPLYPWSEVRDREKQFMPADEAKLMSDIWQSYT
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DLPLATLPKGLCHLDMFADNTLWNLSLNNSQKGEAHLTGLLDFTEVSVEHYVMDIAITIN
CCCHHHHCCHHHEEHEECCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHEEEEEEEEEH
DFCTTWGMAEQGESVNFDRSKMAAFLQGYESKRMLGEDEKRALPVMLAKAAVIFWLLRLN
HHHHHCCCCCCCCCCCCCHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VIHYNRTEGRTGDNIMVKNPDLMKRLAAYHWSHVEKAQNTVFVLLAINNKIEKPIAGVFS
HHEEECCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHH
SITQAEQTCDSLGNSSDFIIKEYTLDQLV
HHHHHHHHHHHCCCCCCEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA