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The map label for this gene is hsdM [C]

Identifier: 93007189

GI number: 93007189

Start: 2902931

End: 2904511

Strand: Reverse

Name: hsdM [C]

Synonym: Pcryo_2365

Alternate gene names: 93007189

Gene position: 2904511-2902931 (Counterclockwise)

Preceding gene: 93007190

Following gene: 93007188

Centisome position: 94.92

GC content: 41.94

Gene sequence:

>1581_bases
ATGGATATTTCAATCAAACAACTCGAAAGTGATCTATGGAACGCGGCTGACAACCTGCGTGCCAACTCAACCCTTACCGC
TGCTGAATATAAAGATCCTTTACTAGGTTTAGTGTTTTTACGATTTGTACAAAATCGCCATGAAGATGCTAAGGTTAAAA
TTCAAGAGTCATTAGCAATCAATCCTCGTACTGGTCAAAAGCGCGAGGTGACCAAAGACGACTTCGTAGCTGCAGGATCG
ATTCTACTACCTGAAAAAGCCAAATATGATTATTTAGCTGCATTACCTGAAAGCGAAAATATCGCTGAGGCAATCAATAA
CGCGATGAAACTCATCGAGGAAGAGTATCCCTCATTAGTAGGTATACTTCCCAAAAACTACCAAGTCTTTGATAATAAGC
TATTACGCGACTTGGTGCGTGTATTTAACAAAGATGCGGTAAGAAAAGCTAAGGGTGATATCTTCGGTCGTATTTATGAA
TTCTTCCTGATGAAGTTCTCTATGCAAGGTGCTGGTGCACAAGAGGGTGGCGAATTCTTCACACCGCCATCACTGGTCAA
TCTGATTGTCAATTTCATTCAACCTGATCATGGCATTATTCATGATCCTGCCTGTGGCTCCGGTGGCATGTTTGTACAGA
CGGCTCATTTCATACAAGGCCATATGCCAAACAAGAGTGTTAACGAGGCTATTACGGTCTATGGTACAGAGCTTAAAAGT
AATAATACTAAGCTTGCTAAGATGAACCTTGCTGTTCATGGTATCGAAGGGGCAATAATAGAGAGTAATAGTTTTTATAC
TAACCCGCATGATCTCAATGGTAAGTGCGATTTTGTCATGGCAAACCCGCCATTTAACGTAAGTGGTATCGATGGGAAAA
ATAAATTTCTCACAGAAGACGCTCGCTTGCCGTTTGGCGCACCTTTGACCAAAGGCGGTACGATCGGTAATGGCAACTAT
TTGTGGATTCAGTATTTCCACAGTTATCTGAATAAGACTGGGCGCGCAGGATTCGTTATGGCATCATCAGCGACTGACGC
AGGTCATGCTGAAAAGCTTATACGTCAGCAGTTGATAGAGACAGGCGATGTCGAGTGTATCGTCTCTATCGCTAATAATT
TCTTTTATACCCGATCACTACCGTGTCACGTTTGGTTCTTTAATAAAGAAAAGAAGGCGGAAAATAAAGACAAAATCTTG
ATGATCGATGCGCGTAACACTTATCGTAAAGTCAGTAGCACGATTCAAGATTTCAGTGAGGATCAATTAGAGGGTCTAAC
AGCGCTAATTAATGCTTTTCGCGGCGATGAGCTTGGCGTTAGTAAAGACAATGAGTGGTTCACTGAGCATTTCCCTGATG
GCACGTATACGGATGTCGAAGGACTATGCAAAGTAGTGGATCTTGATGCTCTAAAAGAGCAAGACTATAGTTTAACGCCA
GGGCGCTATGTGGGCGTAAATATCGATATTGATATGGATTTTGACTATAAAGGGCGTATGACTGAGATCCGCTCAGAGCT
TAGCAGTCTAAATAAAGAAGCAGCTGAGCTTATGAAAAAGATTCAAGGAGTTGAACTATGA

Upstream 100 bases:

>100_bases
ATCAGAGCAATATGCGATACAAAGTGAGCTTTGGAGTTTATAGACCTTCAAACAACCAAATTTAAAACAATTTAAATATA
CGTTAGGAAAACGATAGTTT

Downstream 100 bases:

>100_bases
AGGAAGACTGGAGAGAATATACTATAGATGACGTTGCTAAAATTATTAATGGCTATGCTTTCAAATCAAAAGATTTTATC
AGTTCAGGTGTACCTATTAT

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.MjaXP [H]

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MDISIKQLESDLWNAADNLRANSTLTAAEYKDPLLGLVFLRFVQNRHEDAKVKIQESLAINPRTGQKREVTKDDFVAAGS
ILLPEKAKYDYLAALPESENIAEAINNAMKLIEEEYPSLVGILPKNYQVFDNKLLRDLVRVFNKDAVRKAKGDIFGRIYE
FFLMKFSMQGAGAQEGGEFFTPPSLVNLIVNFIQPDHGIIHDPACGSGGMFVQTAHFIQGHMPNKSVNEAITVYGTELKS
NNTKLAKMNLAVHGIEGAIIESNSFYTNPHDLNGKCDFVMANPPFNVSGIDGKNKFLTEDARLPFGAPLTKGGTIGNGNY
LWIQYFHSYLNKTGRAGFVMASSATDAGHAEKLIRQQLIETGDVECIVSIANNFFYTRSLPCHVWFFNKEKKAENKDKIL
MIDARNTYRKVSSTIQDFSEDQLEGLTALINAFRGDELGVSKDNEWFTEHFPDGTYTDVEGLCKVVDLDALKEQDYSLTP
GRYVGVNIDIDMDFDYKGRMTEIRSELSSLNKEAAELMKKIQGVEL

Sequences:

>Translated_526_residues
MDISIKQLESDLWNAADNLRANSTLTAAEYKDPLLGLVFLRFVQNRHEDAKVKIQESLAINPRTGQKREVTKDDFVAAGS
ILLPEKAKYDYLAALPESENIAEAINNAMKLIEEEYPSLVGILPKNYQVFDNKLLRDLVRVFNKDAVRKAKGDIFGRIYE
FFLMKFSMQGAGAQEGGEFFTPPSLVNLIVNFIQPDHGIIHDPACGSGGMFVQTAHFIQGHMPNKSVNEAITVYGTELKS
NNTKLAKMNLAVHGIEGAIIESNSFYTNPHDLNGKCDFVMANPPFNVSGIDGKNKFLTEDARLPFGAPLTKGGTIGNGNY
LWIQYFHSYLNKTGRAGFVMASSATDAGHAEKLIRQQLIETGDVECIVSIANNFFYTRSLPCHVWFFNKEKKAENKDKIL
MIDARNTYRKVSSTIQDFSEDQLEGLTALINAFRGDELGVSKDNEWFTEHFPDGTYTDVEGLCKVVDLDALKEQDYSLTP
GRYVGVNIDIDMDFDYKGRMTEIRSELSSLNKEAAELMKKIQGVEL
>Mature_526_residues
MDISIKQLESDLWNAADNLRANSTLTAAEYKDPLLGLVFLRFVQNRHEDAKVKIQESLAINPRTGQKREVTKDDFVAAGS
ILLPEKAKYDYLAALPESENIAEAINNAMKLIEEEYPSLVGILPKNYQVFDNKLLRDLVRVFNKDAVRKAKGDIFGRIYE
FFLMKFSMQGAGAQEGGEFFTPPSLVNLIVNFIQPDHGIIHDPACGSGGMFVQTAHFIQGHMPNKSVNEAITVYGTELKS
NNTKLAKMNLAVHGIEGAIIESNSFYTNPHDLNGKCDFVMANPPFNVSGIDGKNKFLTEDARLPFGAPLTKGGTIGNGNY
LWIQYFHSYLNKTGRAGFVMASSATDAGHAEKLIRQQLIETGDVECIVSIANNFFYTRSLPCHVWFFNKEKKAENKDKIL
MIDARNTYRKVSSTIQDFSEDQLEGLTALINAFRGDELGVSKDNEWFTEHFPDGTYTDVEGLCKVVDLDALKEQDYSLTP
GRYVGVNIDIDMDFDYKGRMTEIRSELSSLNKEAAELMKKIQGVEL

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=415, Percent_Identity=23.855421686747, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 58815; Mature: 58815

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDISIKQLESDLWNAADNLRANSTLTAAEYKDPLLGLVFLRFVQNRHEDAKVKIQESLAI
CCCHHHHHHHHHHHHHHCCCCCCEEEHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEEEEE
NPRTGQKREVTKDDFVAAGSILLPEKAKYDYLAALPESENIAEAINNAMKLIEEEYPSLV
CCCCCCCCCCCCHHHHCCCCEECCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCHHE
GILPKNYQVFDNKLLRDLVRVFNKDAVRKAKGDIFGRIYEFFLMKFSMQGAGAQEGGEFF
EECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TPPSLVNLIVNFIQPDHGIIHDPACGSGGMFVQTAHFIQGHMPNKSVNEAITVYGTELKS
CCHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEHHHHHCCCCCCCCCCEEEEEEEEECC
NNTKLAKMNLAVHGIEGAIIESNSFYTNPHDLNGKCDFVMANPPFNVSGIDGKNKFLTED
CCCEEEEEEEEEECCCCEEEECCCEECCCCCCCCEEEEEECCCCCCCCCCCCCCCEECCC
ARLPFGAPLTKGGTIGNGNYLWIQYFHSYLNKTGRAGFVMASSATDAGHAEKLIRQQLIE
CCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHH
TGDVECIVSIANNFFYTRSLPCHVWFFNKEKKAENKDKILMIDARNTYRKVSSTIQDFSE
CCCHHHHEEHHHCEEEECCCCEEEEEECCHHCCCCCCCEEEEECCHHHHHHHHHHHHHHH
DQLEGLTALINAFRGDELGVSKDNEWFTEHFPDGTYTDVEGLCKVVDLDALKEQDYSLTP
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
GRYVGVNIDIDMDFDYKGRMTEIRSELSSLNKEAAELMKKIQGVEL
CCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDISIKQLESDLWNAADNLRANSTLTAAEYKDPLLGLVFLRFVQNRHEDAKVKIQESLAI
CCCHHHHHHHHHHHHHHCCCCCCEEEHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEEEEE
NPRTGQKREVTKDDFVAAGSILLPEKAKYDYLAALPESENIAEAINNAMKLIEEEYPSLV
CCCCCCCCCCCCHHHHCCCCEECCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCHHE
GILPKNYQVFDNKLLRDLVRVFNKDAVRKAKGDIFGRIYEFFLMKFSMQGAGAQEGGEFF
EECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TPPSLVNLIVNFIQPDHGIIHDPACGSGGMFVQTAHFIQGHMPNKSVNEAITVYGTELKS
CCHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEHHHHHCCCCCCCCCCEEEEEEEEECC
NNTKLAKMNLAVHGIEGAIIESNSFYTNPHDLNGKCDFVMANPPFNVSGIDGKNKFLTED
CCCEEEEEEEEEECCCCEEEECCCEECCCCCCCCEEEEEECCCCCCCCCCCCCCCEECCC
ARLPFGAPLTKGGTIGNGNYLWIQYFHSYLNKTGRAGFVMASSATDAGHAEKLIRQQLIE
CCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHH
TGDVECIVSIANNFFYTRSLPCHVWFFNKEKKAENKDKILMIDARNTYRKVSSTIQDFSE
CCCHHHHEEHHHCEEEECCCCEEEEEECCHHCCCCCCCEEEEECCHHHHHHHHHHHHHHH
DQLEGLTALINAFRGDELGVSKDNEWFTEHFPDGTYTDVEGLCKVVDLDALKEQDYSLTP
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
GRYVGVNIDIDMDFDYKGRMTEIRSELSSLNKEAAELMKKIQGVEL
CCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]