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The map label for this gene is znuA [H]

Identifier: 93007159

GI number: 93007159

Start: 2864769

End: 2865698

Strand: Reverse

Name: znuA [H]

Synonym: Pcryo_2335

Alternate gene names: 93007159

Gene position: 2865698-2864769 (Counterclockwise)

Preceding gene: 93007166

Following gene: 93007158

Centisome position: 93.65

GC content: 44.09

Gene sequence:

>930_bases
ATGATTGCCAATTCTCATAAAGCCACGCCGATTGTAGATAACAGCTTAAACGTTCAGGAAAAGAATCTTTTGCATAAGGT
GCAGCAATTAACACAGCAGTACTTCTTAATAGCTAGCTTGTTGATGTTAGGGTTTTTGGCGTTACCAGCTCAAGCGGCAA
CGGTGAGTGTGAGTAATTATCCATTATTTTTGTTAAGCCAAGCAGTTACTGAAGGCGCACCCCCTGCCAAGCAATTATTA
CAAGCAGGAGAGGTAGGGCATCATGGTAGTATCAGCCCCGGCGATATCAAAGCGATTCAGGACAGTACCTTTGTGGTTTG
GTTTGGTGAGCCGTTAGAAAATAACTTGGCAGCAAATTTAAACGACGCGCCTAACTCTATCGCTTTATTTAAGTTTGATG
CTTTTAATCGCCATCCTTTGCGTGATATCAAAGGCAAGCCTATCGCTGGCACGCTTGATCCACATATTTGGTTGGATCCT
AACAACGCCAAAGCCATTACCCGTGCTCTTGCCGTCATACATAGTCATGCCGATCCGCAATATAAAGAACTTTATCATGC
CAATGCACAAAAATTTGCCCAACGTATGGATGCAGCAGTGGCAAACAGTAGTGCTAAACAAAAACCTTTGCCGTATTGGG
CTTATCATGATGCTTATCAATATATGGAAAACAGCATGAACCTACAGCTCATCGGCAGCTTAAGTACTGACGATCATTTA
GCACCAAAAGCCAGTCAATTACGCTGGCTTAACGAGCAGCGCCCCGCTAAGAAAATGTGTCTGGTCAGTCCAAGTGCGCC
TGCCAAAGGTTTACTTGCCAAGTTACAGCCCGTTCAAGAAACCGTTCAGGCAGAAGATATGAGTAATAGTAAGGACTTTG
TCAGTGGGTGGCAAACGATGGCACAGCAGATTCGCCAATGTATATCATAA

Upstream 100 bases:

>100_bases
ATAAAAGTGGGATTTAATTATGTTATAGTATAACATAATGATTGGAAACTTAATATATTAAAGATATCGCAGTTCAATGA
CTTAATAGGATCAATAACGC

Downstream 100 bases:

>100_bases
TGGACTTATTAGAATAAGTGATTGAAACTGTTAATTAAGAATCCCTAAAGACTGTGATATAGTGCCGGTCAAAGACTGGT
TATCTACGCTTAAGTATATG

Product: periplasmic solute binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MIANSHKATPIVDNSLNVQEKNLLHKVQQLTQQYFLIASLLMLGFLALPAQAATVSVSNYPLFLLSQAVTEGAPPAKQLL
QAGEVGHHGSISPGDIKAIQDSTFVVWFGEPLENNLAANLNDAPNSIALFKFDAFNRHPLRDIKGKPIAGTLDPHIWLDP
NNAKAITRALAVIHSHADPQYKELYHANAQKFAQRMDAAVANSSAKQKPLPYWAYHDAYQYMENSMNLQLIGSLSTDDHL
APKASQLRWLNEQRPAKKMCLVSPSAPAKGLLAKLQPVQETVQAEDMSNSKDFVSGWQTMAQQIRQCIS

Sequences:

>Translated_309_residues
MIANSHKATPIVDNSLNVQEKNLLHKVQQLTQQYFLIASLLMLGFLALPAQAATVSVSNYPLFLLSQAVTEGAPPAKQLL
QAGEVGHHGSISPGDIKAIQDSTFVVWFGEPLENNLAANLNDAPNSIALFKFDAFNRHPLRDIKGKPIAGTLDPHIWLDP
NNAKAITRALAVIHSHADPQYKELYHANAQKFAQRMDAAVANSSAKQKPLPYWAYHDAYQYMENSMNLQLIGSLSTDDHL
APKASQLRWLNEQRPAKKMCLVSPSAPAKGLLAKLQPVQETVQAEDMSNSKDFVSGWQTMAQQIRQCIS
>Mature_309_residues
MIANSHKATPIVDNSLNVQEKNLLHKVQQLTQQYFLIASLLMLGFLALPAQAATVSVSNYPLFLLSQAVTEGAPPAKQLL
QAGEVGHHGSISPGDIKAIQDSTFVVWFGEPLENNLAANLNDAPNSIALFKFDAFNRHPLRDIKGKPIAGTLDPHIWLDP
NNAKAITRALAVIHSHADPQYKELYHANAQKFAQRMDAAVANSSAKQKPLPYWAYHDAYQYMENSMNLQLIGSLSTDDHL
APKASQLRWLNEQRPAKKMCLVSPSAPAKGLLAKLQPVQETVQAEDMSNSKDFVSGWQTMAQQIRQCIS

Specific function: Involved in the high-affinity zinc uptake transport system. Required for survival and normal growth under low Zn (2+) concentrations. Also required for virulence and intracellular growth in macrophages [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=234, Percent_Identity=24.3589743589744, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 34037; Mature: 34037

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIANSHKATPIVDNSLNVQEKNLLHKVQQLTQQYFLIASLLMLGFLALPAQAATVSVSNY
CCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
PLFLLSQAVTEGAPPAKQLLQAGEVGHHGSISPGDIKAIQDSTFVVWFGEPLENNLAANL
CHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCEEECCCEEEEEECCCCCCCCCCCC
NDAPNSIALFKFDAFNRHPLRDIKGKPIAGTLDPHIWLDPNNAKAITRALAVIHSHADPQ
CCCCCCEEEEEECCCCCCCCHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCHH
YKELYHANAQKFAQRMDAAVANSSAKQKPLPYWAYHDAYQYMENSMNLQLIGSLSTDDHL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCC
APKASQLRWLNEQRPAKKMCLVSPSAPAKGLLAKLQPVQETVQAEDMSNSKDFVSGWQTM
CCCHHHHHHHHHCCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AQQIRQCIS
HHHHHHHCC
>Mature Secondary Structure
MIANSHKATPIVDNSLNVQEKNLLHKVQQLTQQYFLIASLLMLGFLALPAQAATVSVSNY
CCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
PLFLLSQAVTEGAPPAKQLLQAGEVGHHGSISPGDIKAIQDSTFVVWFGEPLENNLAANL
CHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCEEECCCEEEEEECCCCCCCCCCCC
NDAPNSIALFKFDAFNRHPLRDIKGKPIAGTLDPHIWLDPNNAKAITRALAVIHSHADPQ
CCCCCCEEEEEECCCCCCCCHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCHH
YKELYHANAQKFAQRMDAAVANSSAKQKPLPYWAYHDAYQYMENSMNLQLIGSLSTDDHL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCC
APKASQLRWLNEQRPAKKMCLVSPSAPAKGLLAKLQPVQETVQAEDMSNSKDFVSGWQTM
CCCHHHHHHHHHCCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AQQIRQCIS
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA