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The map label for this gene is atpA [H]

Identifier: 93007153

GI number: 93007153

Start: 2859384

End: 2860928

Strand: Reverse

Name: atpA [H]

Synonym: Pcryo_2329

Alternate gene names: 93007153

Gene position: 2860928-2859384 (Counterclockwise)

Preceding gene: 93007154

Following gene: 93007152

Centisome position: 93.5

GC content: 44.4

Gene sequence:

>1545_bases
ATGCAACAATTGAATCCAGCGGAAATCAGTAACCTGATTAAGCAGCGCATTCAAGACCTTGATGCGGGTGCAACTGCAAA
GAATGAAGGCACGATTGTCAAAGTATCTGACGGTATCGTGCAGATTCATGGTCTTGAAGATGCCATGTACGGCGAAATGA
TTGAGTTTGAAGGTGAAGTCTACGGAATGGCGCTCAACTTAGAGCGTGATTCTGTTGGCGCAGTAGTACTGGGTGACTTC
CTAAAACTACAAGAAGGTCAAAAAGCCTATTGTACTGGTCGTATCCTTGAAGTTCCGGTAGGTCCTGAGTTGCTAGGCCG
TGTTGTTGATGCTTTAGGTAACCCTATTGATGGCAAAGGTCCTATTAATGCCAAAATGACTGACAAAGTTGAGAAGATCG
CTCCAGGCGTTATCGATCGTCAGTCAGTTGATCAGCCAGTAATGACAGGTTATAAGTCTGTTGATACCATGATTCCAATC
GGTCGTGGTCAGCGTGAGCTTATCATTGGTGATCGTCAGACGGGTAAAACCGCGATGGCTATCGATGCGATCATTGCACA
GAAATCATCTGGTATTAAATGTGTCTATGTTGCAATCGGTCAGAAACGTTCTACCATTGCCAACGTCGTACGTAAGCTTG
AGCAAACTGGCGCCCTTGAATATACTACTGTTGTAGTAGCGTCAGCATCAGAGCCAGCAGCACTGCAATATATCGCACCG
TACTCAGGTTGTACGATGGGTGAATACTTCCGTGACCGCGGCGAAGATGCACTGATTGTATTTGATGATTTATCAAAACA
AGCAGTCGCGTATCGTCAAATCTCACTACTATTACGTCGTCCGCCAGGTCGTGAAGCGTATCCTGGTGATGTATTCTATT
TACACTCACGTTTACTTGAGCGTGCATCACGCGTAAACGCGGCGTATGTAGAAAAATTCACCAATGGTGAAGTGGTCGGT
AAAACAGGTTCTTTAACTGCTCTACCTATCATTGAAACCCAAGCAGGTGACGTATCTGCATTTGTACCGACTAACGTGAT
TTCAATCACTGATGGTCAGATTTTCTTAGAGTCAAGCCTATTCAACTCAGGTATCCGTCCGGCTGTGAACGCTGGTATTT
CGGTATCACGTGTTGGTGGTGCGGCTCAGACTAAGATTATTAAGAAACTGTCTGGTGGTATCCGTACCGCACTGGCTCAG
TATCGTGAACTTGCAGCATTCGCTCAGTTTGCATCAGATCTTGATGATGTGACTCGTGAACAGCTTGACCACGGTGAGCG
TGTGACTGAATTGATGAAGCAAAAACAGTATCAGCCAATGTCAATCTCTGAGCAAGCCGCTGTTATCTATGCGTCAAACG
AAGGTTTCTTAGCAGACGTACCAGTTGAAAAAATCGGTTCTTTTGAAGAAGCTTACTTACGCTACATGCATGATGAGCAA
GCTGACTTAATGAAAGAGATTGATGACACTGCGAATTATAACGATGATATCGCAGGTCGTTTAAAGTCTTCTTTAGAGAC
TTTTAAACAAAATCACAGTTATTAA

Upstream 100 bases:

>100_bases
ACGGCCTAATGCCAATCATTAACGTAGCTTAATTAAGCATGCGTGATATAAGAGCATTTACGTCAGTGGCGGGTTATCAT
AAATTAAAGGAAACAAGGCA

Downstream 100 bases:

>100_bases
TTTAACGGGTTAAGCCAGTTTTGTTGTGGCTTTAGTGTTAGAGCTTATGGAGTGGCGCGTTGTCTGATAAGCTTTTTATT
AAGACAGCAGCGCCACTTTA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MQQLNPAEISNLIKQRIQDLDAGATAKNEGTIVKVSDGIVQIHGLEDAMYGEMIEFEGEVYGMALNLERDSVGAVVLGDF
LKLQEGQKAYCTGRILEVPVGPELLGRVVDALGNPIDGKGPINAKMTDKVEKIAPGVIDRQSVDQPVMTGYKSVDTMIPI
GRGQRELIIGDRQTGKTAMAIDAIIAQKSSGIKCVYVAIGQKRSTIANVVRKLEQTGALEYTTVVVASASEPAALQYIAP
YSGCTMGEYFRDRGEDALIVFDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVNAAYVEKFTNGEVVG
KTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSLFNSGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRTALAQ
YRELAAFAQFASDLDDVTREQLDHGERVTELMKQKQYQPMSISEQAAVIYASNEGFLADVPVEKIGSFEEAYLRYMHDEQ
ADLMKEIDDTANYNDDIAGRLKSSLETFKQNHSY

Sequences:

>Translated_514_residues
MQQLNPAEISNLIKQRIQDLDAGATAKNEGTIVKVSDGIVQIHGLEDAMYGEMIEFEGEVYGMALNLERDSVGAVVLGDF
LKLQEGQKAYCTGRILEVPVGPELLGRVVDALGNPIDGKGPINAKMTDKVEKIAPGVIDRQSVDQPVMTGYKSVDTMIPI
GRGQRELIIGDRQTGKTAMAIDAIIAQKSSGIKCVYVAIGQKRSTIANVVRKLEQTGALEYTTVVVASASEPAALQYIAP
YSGCTMGEYFRDRGEDALIVFDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVNAAYVEKFTNGEVVG
KTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSLFNSGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRTALAQ
YRELAAFAQFASDLDDVTREQLDHGERVTELMKQKQYQPMSISEQAAVIYASNEGFLADVPVEKIGSFEEAYLRYMHDEQ
ADLMKEIDDTANYNDDIAGRLKSSLETFKQNHSY
>Mature_514_residues
MQQLNPAEISNLIKQRIQDLDAGATAKNEGTIVKVSDGIVQIHGLEDAMYGEMIEFEGEVYGMALNLERDSVGAVVLGDF
LKLQEGQKAYCTGRILEVPVGPELLGRVVDALGNPIDGKGPINAKMTDKVEKIAPGVIDRQSVDQPVMTGYKSVDTMIPI
GRGQRELIIGDRQTGKTAMAIDAIIAQKSSGIKCVYVAIGQKRSTIANVVRKLEQTGALEYTTVVVASASEPAALQYIAP
YSGCTMGEYFRDRGEDALIVFDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVNAAYVEKFTNGEVVG
KTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSLFNSGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRTALAQ
YRELAAFAQFASDLDDVTREQLDHGERVTELMKQKQYQPMSISEQAAVIYASNEGFLADVPVEKIGSFEEAYLRYMHDEQ
ADLMKEIDDTANYNDDIAGRLKSSLETFKQNHSY

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=516, Percent_Identity=55.6201550387597, Blast_Score=570, Evalue=1e-162,
Organism=Homo sapiens, GI4757810, Length=516, Percent_Identity=55.6201550387597, Blast_Score=570, Evalue=1e-162,
Organism=Homo sapiens, GI32189394, Length=328, Percent_Identity=27.1341463414634, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI19913426, Length=323, Percent_Identity=27.5541795665635, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI19913428, Length=317, Percent_Identity=27.4447949526814, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI19913424, Length=262, Percent_Identity=29.0076335877863, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1790172, Length=512, Percent_Identity=74.8046875, Blast_Score=786, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=388, Percent_Identity=25.2577319587629, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788251, Length=281, Percent_Identity=25.6227758007117, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=515, Percent_Identity=55.3398058252427, Blast_Score=565, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI71988080, Length=515, Percent_Identity=55.3398058252427, Blast_Score=565, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI71988074, Length=515, Percent_Identity=51.8446601941748, Blast_Score=519, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI17510931, Length=384, Percent_Identity=26.0416666666667, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17570191, Length=311, Percent_Identity=26.6881028938907, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25144756, Length=305, Percent_Identity=27.2131147540984, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17565854, Length=254, Percent_Identity=26.7716535433071, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=60, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=511, Percent_Identity=54.4031311154599, Blast_Score=565, Evalue=1e-162,
Organism=Saccharomyces cerevisiae, GI6319603, Length=315, Percent_Identity=29.5238095238095, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6322581, Length=331, Percent_Identity=27.190332326284, Blast_Score=111, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320016, Length=309, Percent_Identity=25.2427184466019, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24658560, Length=510, Percent_Identity=55.8823529411765, Blast_Score=560, Evalue=1e-160,
Organism=Drosophila melanogaster, GI281361666, Length=314, Percent_Identity=27.0700636942675, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24646341, Length=314, Percent_Identity=27.0700636942675, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17136796, Length=314, Percent_Identity=27.0700636942675, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24638766, Length=418, Percent_Identity=25.3588516746411, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28574560, Length=410, Percent_Identity=24.6341463414634, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24583988, Length=255, Percent_Identity=27.4509803921569, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24583986, Length=255, Percent_Identity=27.4509803921569, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24583984, Length=255, Percent_Identity=27.4509803921569, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24583992, Length=255, Percent_Identity=27.4509803921569, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20129479, Length=255, Percent_Identity=27.843137254902, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55965; Mature: 55965

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLNPAEISNLIKQRIQDLDAGATAKNEGTIVKVSDGIVQIHGLEDAMYGEMIEFEGEV
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEECCCHHHHHHHEEECCEE
YGMALNLERDSVGAVVLGDFLKLQEGQKAYCTGRILEVPVGPELLGRVVDALGNPIDGKG
EEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCEEEECCCCHHHHHHHHHHHCCCCCCCC
PINAKMTDKVEKIAPGVIDRQSVDQPVMTGYKSVDTMIPIGRGQRELIIGDRQTGKTAMA
CCCCCHHHHHHHHCCCCCCHHCCCCHHHHCHHHHHCEECCCCCCEEEEEECCCCCCHHHH
IDAIIAQKSSGIKCVYVAIGQKRSTIANVVRKLEQTGALEYTTVVVASASEPAALQYIAP
HHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEECC
YSGCTMGEYFRDRGEDALIVFDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLE
CCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RASRVNAAYVEKFTNGEVVGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSL
HHHHCCHHHHHHCCCCCEEECCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEEHHH
FNSGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFAQFASDLDDVTRE
HCCCCCHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLDHGERVTELMKQKQYQPMSISEQAAVIYASNEGFLADVPVEKIGSFEEAYLRYMHDEQ
HHHCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEECCHHHHCCHHHHHHHHHCCHH
ADLMKEIDDTANYNDDIAGRLKSSLETFKQNHSY
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQQLNPAEISNLIKQRIQDLDAGATAKNEGTIVKVSDGIVQIHGLEDAMYGEMIEFEGEV
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEECCCHHHHHHHEEECCEE
YGMALNLERDSVGAVVLGDFLKLQEGQKAYCTGRILEVPVGPELLGRVVDALGNPIDGKG
EEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCEEEECCCCHHHHHHHHHHHCCCCCCCC
PINAKMTDKVEKIAPGVIDRQSVDQPVMTGYKSVDTMIPIGRGQRELIIGDRQTGKTAMA
CCCCCHHHHHHHHCCCCCCHHCCCCHHHHCHHHHHCEECCCCCCEEEEEECCCCCCHHHH
IDAIIAQKSSGIKCVYVAIGQKRSTIANVVRKLEQTGALEYTTVVVASASEPAALQYIAP
HHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEECC
YSGCTMGEYFRDRGEDALIVFDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLE
CCCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RASRVNAAYVEKFTNGEVVGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSL
HHHHCCHHHHHHCCCCCEEECCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEEHHH
FNSGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFAQFASDLDDVTRE
HCCCCCHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLDHGERVTELMKQKQYQPMSISEQAAVIYASNEGFLADVPVEKIGSFEEAYLRYMHDEQ
HHHCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEECCHHHHCCHHHHHHHHHCCHH
ADLMKEIDDTANYNDDIAGRLKSSLETFKQNHSY
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA