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The map label for this gene is lytH [H]

Identifier: 93007038

GI number: 93007038

Start: 2719231

End: 2719827

Strand: Direct

Name: lytH [H]

Synonym: Pcryo_2214

Alternate gene names: 93007038

Gene position: 2719231-2719827 (Clockwise)

Preceding gene: 93007036

Following gene: 93007042

Centisome position: 88.87

GC content: 46.4

Gene sequence:

>597_bases
ATGTCGATGCGACCAGATGGCAATCACGAACAACCAAATCCTACATTTATCAGCCGCGCAATTAGCGTACTCATCAAGGC
CGCAGTATTGCTGATGCTATTATTCGTATTTGACAGATTATTACCGAGTATCAGCCAACAAACTCAATCATTTTTCATAG
CAAAATGGCAGCAGCTTAGCCTATTGCAACATCCGCTACCAACAGAGAATAGCCTGCCAAATCCGCTACCCAAGCAGCCT
CTAACAGATACGTGGGGCGCTGCTCGTAGTCAAGGTCGCTCACATGAAGGGATTGATATTTTTGCAGCGCGCGGCACGCC
AATACAAGCAACGACCCAAGGTATCGTTAGCAAGGTAGGCGAAAATACGTTAGGAGGTCGCATCGTTGTGATAGTAGGAC
CTGGCGGCGCCGGACACTATTATGCACATTTGGAAAACTATGCTGACATTTCTCCCAATGACTGGGTAAATGCCGGTGAT
ACCATTGGTTACGTGGGTGATAGCGGCAATGCTAAAGGCACACCGCCGCATGTTCATTATGGAATTTATATTAATGGTAG
CGCGGTAAATCCTTATCCACTTTTGCAAAAGGATTAA

Upstream 100 bases:

>100_bases
TTTTTATTTATGGGGATAAAAGTCAGGTATAACAATGCTATACGAAGAGCCAAAGGTAATATCTATATAATATTAGTGAA
AGCAATAACAAGACAAAGAG

Downstream 100 bases:

>100_bases
AGTGTATCAAGCATTAATTTATTGCGGCAGATCGTACATGGTTATTTGGGAACACGGCACTAAATGTCGAGCCAATGCCT
TCTACTGACTCAATTTGCAA

Product: peptidase M23B

Products: NA

Alternate protein names: Peptidoglycan hydrolase; Sporulation-specific endopeptidase [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MSMRPDGNHEQPNPTFISRAISVLIKAAVLLMLLFVFDRLLPSISQQTQSFFIAKWQQLSLLQHPLPTENSLPNPLPKQP
LTDTWGAARSQGRSHEGIDIFAARGTPIQATTQGIVSKVGENTLGGRIVVIVGPGGAGHYYAHLENYADISPNDWVNAGD
TIGYVGDSGNAKGTPPHVHYGIYINGSAVNPYPLLQKD

Sequences:

>Translated_198_residues
MSMRPDGNHEQPNPTFISRAISVLIKAAVLLMLLFVFDRLLPSISQQTQSFFIAKWQQLSLLQHPLPTENSLPNPLPKQP
LTDTWGAARSQGRSHEGIDIFAARGTPIQATTQGIVSKVGENTLGGRIVVIVGPGGAGHYYAHLENYADISPNDWVNAGD
TIGYVGDSGNAKGTPPHVHYGIYINGSAVNPYPLLQKD
>Mature_197_residues
SMRPDGNHEQPNPTFISRAISVLIKAAVLLMLLFVFDRLLPSISQQTQSFFIAKWQQLSLLQHPLPTENSLPNPLPKQPL
TDTWGAARSQGRSHEGIDIFAARGTPIQATTQGIVSKVGENTLGGRIVVIVGPGGAGHYYAHLENYADISPNDWVNAGDT
IGYVGDSGNAKGTPPHVHYGIYINGSAVNPYPLLQKD

Specific function: L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore, is required for the endospore cortex maturation [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047 [H]

Pfam domain/function: PF01551 Peptidase_M23 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 21406; Mature: 21274

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMRPDGNHEQPNPTFISRAISVLIKAAVLLMLLFVFDRLLPSISQQTQSFFIAKWQQLS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQHPLPTENSLPNPLPKQPLTDTWGAARSQGRSHEGIDIFAARGTPIQATTQGIVSKVG
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHC
ENTLGGRIVVIVGPGGAGHYYAHLENYADISPNDWVNAGDTIGYVGDSGNAKGTPPHVHY
CCCCCCEEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEE
GIYINGSAVNPYPLLQKD
EEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SMRPDGNHEQPNPTFISRAISVLIKAAVLLMLLFVFDRLLPSISQQTQSFFIAKWQQLS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQHPLPTENSLPNPLPKQPLTDTWGAARSQGRSHEGIDIFAARGTPIQATTQGIVSKVG
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHC
ENTLGGRIVVIVGPGGAGHYYAHLENYADISPNDWVNAGDTIGYVGDSGNAKGTPPHVHY
CCCCCCEEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEE
GIYINGSAVNPYPLLQKD
EEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12813075 [H]