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The map label for this gene is pilQ [H]

Identifier: 93006993

GI number: 93006993

Start: 2661288

End: 2663666

Strand: Reverse

Name: pilQ [H]

Synonym: Pcryo_2169

Alternate gene names: 93006993

Gene position: 2663666-2661288 (Counterclockwise)

Preceding gene: 93006994

Following gene: 93006992

Centisome position: 87.05

GC content: 44.43

Gene sequence:

>2379_bases
ATGACAGTACGCAATAACAAGGTAATGACGATGAGCAACCGCGTATCTTCTACTTTTGCCATCTCTGCATTGGCAATGAG
TATGGTAGCTGTAAGTAGCATTGCCCATGCCGAGCAGCGCATCAACAATGTCTCTGTGGTGCAGACTGCGCCAGCCGTAA
CGCAAATGCGTTTAGGGTTTTCAGGTGCGCCAGTATTACCAGCCGCTTATCAGCTCGACAATCCTAGCCGTTTGGTGCTG
GATTTTGAACAGGTGCAAAACGGTCTTGCTAGTCGCTTTAAAGAATATAATATCGGTATGGTCAATGAGGTCACCACCTT
AAATAGTGACAATACCACCCGTCTTATCGTTGGGCTAAAAAAGACGGGCAACTATACCACCGCGATTGATGGCAATGAAT
TATTGCTGACGATTACGGACCCTAATCGTCCAGTGATTGCTCCGGTGGTCACGAAAGTCATTACCAACGACCCTGTACAA
GATGTCCTAAATGGCAATTCGGCTATTACTACCACGGCTGTGGTTACGCCCATTGTTGAAACCAGTAGCGTTGCTGTCCC
GCCTATTAGAACCACAGTCACAAAAAACCAAGTACCTGCTGACACCATGGTCGTACGTGTCAACCCTTTATTAAGCCCAC
AACTTGCCTCTGCACAAGTCAGCAAGCAGTATAGCTATGATGGGCTAAGCGCTGTGAATTTTTCAGCAGGGAATGATGGC
GGTGGTAACGTTAGTATCTCACTTGCCAATGAAGCGATTCCTGTAGACGTTCAGCGTCAAGGTAATAAGCTGGTTGTGCG
TTTGACAGGCAGTACCGTACCTAGAAATCTGCTACGCCGATTGAATGTTAATGGTGGTTTGGTAGACAGTATTGATACTA
AAAACCAAGGTCAAAATGGTGTTATTACCATCAATATGAAAGACGATTTTGAATATCAAGCCTATCAATCAGGCAGTCAG
CTAAATATTGGTATCAGACGACCTGAGCTGCTACGTGAGCCGACGCTTGAAGAAAAAGTCTATACCGGTGCAGCGCTATC
TATGGAGTTTCAAGATGTTGAGATTCGTAGTGTCCTAGATATCTTAGCGCAGTTTACAGAGATGAATATCGTTGCTAGTG
ATTCGGTCGCCGGTAATATTACCTTGCGCCTTATCAACGTACCTTGGGATCAAGCACTTGATATCATTCTTAAAAGTAAA
AATTTGGGCAAACGTGAAAACGGTAACGTAATTTTGGTTGCGCCTTCAACTGAGCTTGCTGAACAAGAAGCACGTGAGCT
TGAAGCCCAGCAAGCGGTTGAGTCTTATGCACCGTTACGTACTGAATATATCCGTCTAAGCTACGCAAAAGCGGCAGATG
TCCTAACCCTGATCTCTCAAGGTAGTGGTGGTGCCTCTGGCGGTAGCAATACTGGCAGCGCCAATGCTAATACTAAAGAT
AGCAATAGCTTGCTCTCTAATCGTGGAACAGTAACAGTCGATGAGCGTACCAATACTCTGATTGTTAAAGATGTGGCAGC
CAGCATTGAAAATATCCATAAGCTGATTGGTAAAATCGACATTCCTGTCCGTCAGGTCATGATTGAAGCGCGTATCGTTA
GCGCGACTGATAGCTTTAGTAAAGAGATTGGAGTGCGTTGGGGTATCTTGTCAAATGGCGCTGCCAATAACCGGAACTTG
TTGGTCGGTGGCAGTAACCAAACTTTATGGGACTTAAAAGATTTTGATGTGCAGACCACGACTATTAATGGTCAGACCGT
CTCTTATCCTAAATACGATATTACTCGTCCTGACAATCTAAACGTTGACTTAGGCGTTGATAATCCAGCAGGTCGTATTG
CCTTTGGTCTGCTAGGTATTTCTGATTTTATGCTCGATCTTGAGTTGTCAGCCATGCAAGCAGACAACCGCGGTGAAGTG
ATTTCTACGCCAAAGATTTTGACCTCTGATAAGCAAACGGCAAAAGTATCTTCTGGTACGCAGATTCCTTATCAAGAAGC
ATCAGCAAGTGGTGCGACTACTACTAGCTTTAAAGAAGCTGCTTTAAGTTTGGAAGCCACGCCAAATATTACTCCAGATG
GTAAGATTGGTTTGCAACTGTTAATCACCAATGGCACACCGACCATTATTAATAATCAGGTTGCCATCGCTGAAGACTCG
ATTTCTACTAACGTTATTGTTGAAGATGGTCAAACCATTGTATTGGGCGGCGTCTTTAAAAACCGTACTAATAATGGCGT
CGATAAAGTACCTTTCTTAGGTGATTTGCCTTATATCGGTCGTGCCTTCCGTAAAGACGTGCGCAGCAATACCAAAGAAG
AGCTGCTGATATTTATCACGCCGAAACTGATCAATGATGGTATTAGTCGCTTAGATTAG

Upstream 100 bases:

>100_bases
GATTGAAATTGTGCCAGACAGCCGTGCTGGGTTTGTTGAAAAACCCCAGTCACTGGTGTCCCCTATAAGCTAAGTCGGCA
GATTTTTTGAGGAATAAATA

Downstream 100 bases:

>100_bases
TCAGATTTTAGTTGGTTTTGAGTCATAAAAAGCAAGCCTTAGTGCTTGCTTTTTTAATGGTTGATTTTTAGGCTGGCAAG
GATTTTACTAACAATAATCA

Product: type II and III secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 792; Mature: 791

Protein sequence:

>792_residues
MTVRNNKVMTMSNRVSSTFAISALAMSMVAVSSIAHAEQRINNVSVVQTAPAVTQMRLGFSGAPVLPAAYQLDNPSRLVL
DFEQVQNGLASRFKEYNIGMVNEVTTLNSDNTTRLIVGLKKTGNYTTAIDGNELLLTITDPNRPVIAPVVTKVITNDPVQ
DVLNGNSAITTTAVVTPIVETSSVAVPPIRTTVTKNQVPADTMVVRVNPLLSPQLASAQVSKQYSYDGLSAVNFSAGNDG
GGNVSISLANEAIPVDVQRQGNKLVVRLTGSTVPRNLLRRLNVNGGLVDSIDTKNQGQNGVITINMKDDFEYQAYQSGSQ
LNIGIRRPELLREPTLEEKVYTGAALSMEFQDVEIRSVLDILAQFTEMNIVASDSVAGNITLRLINVPWDQALDIILKSK
NLGKRENGNVILVAPSTELAEQEARELEAQQAVESYAPLRTEYIRLSYAKAADVLTLISQGSGGASGGSNTGSANANTKD
SNSLLSNRGTVTVDERTNTLIVKDVAASIENIHKLIGKIDIPVRQVMIEARIVSATDSFSKEIGVRWGILSNGAANNRNL
LVGGSNQTLWDLKDFDVQTTTINGQTVSYPKYDITRPDNLNVDLGVDNPAGRIAFGLLGISDFMLDLELSAMQADNRGEV
ISTPKILTSDKQTAKVSSGTQIPYQEASASGATTTSFKEAALSLEATPNITPDGKIGLQLLITNGTPTIINNQVAIAEDS
ISTNVIVEDGQTIVLGGVFKNRTNNGVDKVPFLGDLPYIGRAFRKDVRSNTKEELLIFITPKLINDGISRLD

Sequences:

>Translated_792_residues
MTVRNNKVMTMSNRVSSTFAISALAMSMVAVSSIAHAEQRINNVSVVQTAPAVTQMRLGFSGAPVLPAAYQLDNPSRLVL
DFEQVQNGLASRFKEYNIGMVNEVTTLNSDNTTRLIVGLKKTGNYTTAIDGNELLLTITDPNRPVIAPVVTKVITNDPVQ
DVLNGNSAITTTAVVTPIVETSSVAVPPIRTTVTKNQVPADTMVVRVNPLLSPQLASAQVSKQYSYDGLSAVNFSAGNDG
GGNVSISLANEAIPVDVQRQGNKLVVRLTGSTVPRNLLRRLNVNGGLVDSIDTKNQGQNGVITINMKDDFEYQAYQSGSQ
LNIGIRRPELLREPTLEEKVYTGAALSMEFQDVEIRSVLDILAQFTEMNIVASDSVAGNITLRLINVPWDQALDIILKSK
NLGKRENGNVILVAPSTELAEQEARELEAQQAVESYAPLRTEYIRLSYAKAADVLTLISQGSGGASGGSNTGSANANTKD
SNSLLSNRGTVTVDERTNTLIVKDVAASIENIHKLIGKIDIPVRQVMIEARIVSATDSFSKEIGVRWGILSNGAANNRNL
LVGGSNQTLWDLKDFDVQTTTINGQTVSYPKYDITRPDNLNVDLGVDNPAGRIAFGLLGISDFMLDLELSAMQADNRGEV
ISTPKILTSDKQTAKVSSGTQIPYQEASASGATTTSFKEAALSLEATPNITPDGKIGLQLLITNGTPTIINNQVAIAEDS
ISTNVIVEDGQTIVLGGVFKNRTNNGVDKVPFLGDLPYIGRAFRKDVRSNTKEELLIFITPKLINDGISRLD
>Mature_791_residues
TVRNNKVMTMSNRVSSTFAISALAMSMVAVSSIAHAEQRINNVSVVQTAPAVTQMRLGFSGAPVLPAAYQLDNPSRLVLD
FEQVQNGLASRFKEYNIGMVNEVTTLNSDNTTRLIVGLKKTGNYTTAIDGNELLLTITDPNRPVIAPVVTKVITNDPVQD
VLNGNSAITTTAVVTPIVETSSVAVPPIRTTVTKNQVPADTMVVRVNPLLSPQLASAQVSKQYSYDGLSAVNFSAGNDGG
GNVSISLANEAIPVDVQRQGNKLVVRLTGSTVPRNLLRRLNVNGGLVDSIDTKNQGQNGVITINMKDDFEYQAYQSGSQL
NIGIRRPELLREPTLEEKVYTGAALSMEFQDVEIRSVLDILAQFTEMNIVASDSVAGNITLRLINVPWDQALDIILKSKN
LGKRENGNVILVAPSTELAEQEARELEAQQAVESYAPLRTEYIRLSYAKAADVLTLISQGSGGASGGSNTGSANANTKDS
NSLLSNRGTVTVDERTNTLIVKDVAASIENIHKLIGKIDIPVRQVMIEARIVSATDSFSKEIGVRWGILSNGAANNRNLL
VGGSNQTLWDLKDFDVQTTTINGQTVSYPKYDITRPDNLNVDLGVDNPAGRIAFGLLGISDFMLDLELSAMQADNRGEVI
STPKILTSDKQTAKVSSGTQIPYQEASASGATTTSFKEAALSLEATPNITPDGKIGLQLLITNGTPTIINNQVAIAEDSI
STNVIVEDGQTIVLGGVFKNRTNNGVDKVPFLGDLPYIGRAFRKDVRSNTKEELLIFITPKLINDGISRLD

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=444, Percent_Identity=32.2072072072072, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI87082242, Length=407, Percent_Identity=25.5528255528256, Blast_Score=106, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 85026; Mature: 84895

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRNNKVMTMSNRVSSTFAISALAMSMVAVSSIAHAEQRINNVSVVQTAPAVTQMRLGF
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHEECCC
SGAPVLPAAYQLDNPSRLVLDFEQVQNGLASRFKEYNIGMVNEVTTLNSDNTTRLIVGLK
CCCCCCCCEEECCCCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEEE
KTGNYTTAIDGNELLLTITDPNRPVIAPVVTKVITNDPVQDVLNGNSAITTTAVVTPIVE
CCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHCCCCEEEEEEEEEEEEC
TSSVAVPPIRTTVTKNQVPADTMVVRVNPLLSPQLASAQVSKQYSYDGLSAVNFSAGNDG
CCCEECCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCC
GGNVSISLANEAIPVDVQRQGNKLVVRLTGSTVPRNLLRRLNVNGGLVDSIDTKNQGQNG
CCEEEEEECCCCCEEEEECCCCEEEEEECCCCCHHHHHHHCCCCCCEEECCCCCCCCCCC
VITINMKDDFEYQAYQSGSQLNIGIRRPELLREPTLEEKVYTGAALSMEFQDVEIRSVLD
EEEEEECCCCCCHHHCCCCEEEEECCCHHHHCCCCHHHHHCCCEEEEEEECCCHHHHHHH
ILAQFTEMNIVASDSVAGNITLRLINVPWDQALDIILKSKNLGKRENGNVILVAPSTELA
HHHHHHHCEEEECCCCCCEEEEEEEECCHHHHHHHEEECCCCCCCCCCCEEEEECCHHHH
EQEARELEAQQAVESYAPLRTEYIRLSYAKAADVLTLISQGSGGASGGSNTGSANANTKD
HHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
SNSLLSNRGTVTVDERTNTLIVKDVAASIENIHKLIGKIDIPVRQVMIEARIVSATDSFS
CHHHHHCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHEEHEEEECCHHHH
KEIGVRWGILSNGAANNRNLLVGGSNQTLWDLKDFDVQTTTINGQTVSYPKYDITRPDNL
HHHCEEEEEECCCCCCCCEEEEECCCCEEEECCCCCEEEEEECCEEEECCCCCCCCCCCC
NVDLGVDNPAGRIAFGLLGISDFMLDLELSAMQADNRGEVISTPKILTSDKQTAKVSSGT
EEEECCCCCCCHHEEEHHHHHHHHEEEEEHEECCCCCCCEEECCCEEECCCCCEECCCCC
QIPYQEASASGATTTSFKEAALSLEATPNITPDGKIGLQLLITNGTPTIINNQVAIAEDS
CCCHHHCCCCCCCCCCHHHHHEEEECCCCCCCCCCCEEEEEEECCCCEEECCEEEEEECC
ISTNVIVEDGQTIVLGGVFKNRTNNGVDKVPFLGDLPYIGRAFRKDVRSNTKEELLIFIT
CCCEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEE
PKLINDGISRLD
HHHHHHHHHHCC
>Mature Secondary Structure 
TVRNNKVMTMSNRVSSTFAISALAMSMVAVSSIAHAEQRINNVSVVQTAPAVTQMRLGF
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHEECCC
SGAPVLPAAYQLDNPSRLVLDFEQVQNGLASRFKEYNIGMVNEVTTLNSDNTTRLIVGLK
CCCCCCCCEEECCCCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEEE
KTGNYTTAIDGNELLLTITDPNRPVIAPVVTKVITNDPVQDVLNGNSAITTTAVVTPIVE
CCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHHCCCCHHHHHCCCCEEEEEEEEEEEEC
TSSVAVPPIRTTVTKNQVPADTMVVRVNPLLSPQLASAQVSKQYSYDGLSAVNFSAGNDG
CCCEECCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCC
GGNVSISLANEAIPVDVQRQGNKLVVRLTGSTVPRNLLRRLNVNGGLVDSIDTKNQGQNG
CCEEEEEECCCCCEEEEECCCCEEEEEECCCCCHHHHHHHCCCCCCEEECCCCCCCCCCC
VITINMKDDFEYQAYQSGSQLNIGIRRPELLREPTLEEKVYTGAALSMEFQDVEIRSVLD
EEEEEECCCCCCHHHCCCCEEEEECCCHHHHCCCCHHHHHCCCEEEEEEECCCHHHHHHH
ILAQFTEMNIVASDSVAGNITLRLINVPWDQALDIILKSKNLGKRENGNVILVAPSTELA
HHHHHHHCEEEECCCCCCEEEEEEEECCHHHHHHHEEECCCCCCCCCCCEEEEECCHHHH
EQEARELEAQQAVESYAPLRTEYIRLSYAKAADVLTLISQGSGGASGGSNTGSANANTKD
HHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
SNSLLSNRGTVTVDERTNTLIVKDVAASIENIHKLIGKIDIPVRQVMIEARIVSATDSFS
CHHHHHCCCCEEECCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHEEHEEEECCHHHH
KEIGVRWGILSNGAANNRNLLVGGSNQTLWDLKDFDVQTTTINGQTVSYPKYDITRPDNL
HHHCEEEEEECCCCCCCCEEEEECCCCEEEECCCCCEEEEEECCEEEECCCCCCCCCCCC
NVDLGVDNPAGRIAFGLLGISDFMLDLELSAMQADNRGEVISTPKILTSDKQTAKVSSGT
EEEECCCCCCCHHEEEHHHHHHHHEEEEEHEECCCCCCCEEECCCEEECCCCCEECCCCC
QIPYQEASASGATTTSFKEAALSLEATPNITPDGKIGLQLLITNGTPTIINNQVAIAEDS
CCCHHHCCCCCCCCCCHHHHHEEEECCCCCCCCCCCEEEEEEECCCCEEECCEEEEEECC
ISTNVIVEDGQTIVLGGVFKNRTNNGVDKVPFLGDLPYIGRAFRKDVRSNTKEELLIFIT
CCCEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEE
PKLINDGISRLD
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]