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The map label for this gene is argE [H]

Identifier: 93006873

GI number: 93006873

Start: 2518471

End: 2519721

Strand: Reverse

Name: argE [H]

Synonym: Pcryo_2049

Alternate gene names: 93006873

Gene position: 2519721-2518471 (Counterclockwise)

Preceding gene: 93006874

Following gene: 93006872

Centisome position: 82.35

GC content: 45.08

Gene sequence:

>1251_bases
ATGACTGTATCAACTCGTACTGATGGCTTATCTCACGCTGTAATGGATACTGATTATCCATCGAATAGCATTGACTGGCT
TACAAGGCTGATTGCTTTTGATACGGTCAGTCGCCATTCAAACTTGGCATTGATTGAAGACGTGCAACGCTATTGTGAGC
AATTAGGCTTAAGCGTAGATTTGACCTTTAATGATGCCAAAAATAAAGCCAATTTATTTGTCACCGTAGCAGCAGGTGGT
AATGCTAATAGCAGTGCTGATATCATCAATCATGGTTTGGTGCTATCAGGGCATACTGATGTCGTACCAGTTGATGGTCA
AGCATGGACATCAGAGCCATTTACTGCGACGATTCGTGGTGACAAGCTATATGGACGCGGTGCTTGCGATATGAAAGGCT
TTATTGCGTGTGCGCTAACTTTATTACCAAAAGCGGTGAAGTTATCGAGTAGTGGTCAGCTGAGTCGTCCTCTTCATTTG
GCATTGTCATTTGATGAAGAGGTTGGCTGCTTGGGTGCGCCATTAATTTTGGCAGACTTAAAAGCTCGCGGTATTACGCC
TGATTATTGTATCGTCGGTGAGCCCACCAATATGGCAATGGTCGTGGCGCATAAAGGTATTGCTGTTTATCGCTGCCGCG
TCCACGGCAAATCTGCGCACTCATCATTAACAGCAACAGGTGTAAACGCCATCAGTTATGCCAGTCGTTTGATTGGCTAT
GTTGATACCTTGGCAGAAGAAATAAGCCATCGTGATGATAATGATGCACTGTTCGATGTCCCTTATTCGACATTGTCTGT
GGGCACCATACAAGGTGGTACAGCGACCAATATTGTGCCCAATTTGTGTGAGTTCACCTTTGATTATCGCAACCTGCCAC
ATATGACGCAGGACGACATTCTGCTACCGATTCAAGCAAAAGTTGCAGAATTAAGCGCACAAATGCAAGCGCGCGCTGCC
GATACCGGCATTGAGCTGACACAAGAAGAAAGCGTACCGGCAATGACAGATAATGATAGTGCCGAGCTACAAGCATTGAT
AGCAGCACTGACAGGTGACACTCAACGCCATAAAGTTGCTTACGCTACTGAAGGCGGGCAGTTTACTAATAGCGGTATCC
CAACGATTATCTGTGGTCCCGGCAGTATTGAGCAGGCGCATAAAGCCGATGAATATGTTAAGTTAAATGAGATTGAGCGC
TGTGATAGCTTCTTACAGCGTCTATTAGAAAGTTGTACTATGGATAAATAA

Upstream 100 bases:

>100_bases
GGTCCGATTGCTGGATTAGATGCAGAAGTAAAAATGCTGCAACAACGTGCATTTCAAAGACGCTAAGCTCTTTTTATCTT
TATCGTATTAAGGATTTTTT

Downstream 100 bases:

>100_bases
ACCGCAAGGTTTAGGTCGTGGTTGGTATAATAAACACCGTCTTTATGGCGGTGTTTATTTTTTCGTTCAGTCAGTTTAAA
ATAAAAAAGTAAGGGTTGGT

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MTVSTRTDGLSHAVMDTDYPSNSIDWLTRLIAFDTVSRHSNLALIEDVQRYCEQLGLSVDLTFNDAKNKANLFVTVAAGG
NANSSADIINHGLVLSGHTDVVPVDGQAWTSEPFTATIRGDKLYGRGACDMKGFIACALTLLPKAVKLSSSGQLSRPLHL
ALSFDEEVGCLGAPLILADLKARGITPDYCIVGEPTNMAMVVAHKGIAVYRCRVHGKSAHSSLTATGVNAISYASRLIGY
VDTLAEEISHRDDNDALFDVPYSTLSVGTIQGGTATNIVPNLCEFTFDYRNLPHMTQDDILLPIQAKVAELSAQMQARAA
DTGIELTQEESVPAMTDNDSAELQALIAALTGDTQRHKVAYATEGGQFTNSGIPTIICGPGSIEQAHKADEYVKLNEIER
CDSFLQRLLESCTMDK

Sequences:

>Translated_416_residues
MTVSTRTDGLSHAVMDTDYPSNSIDWLTRLIAFDTVSRHSNLALIEDVQRYCEQLGLSVDLTFNDAKNKANLFVTVAAGG
NANSSADIINHGLVLSGHTDVVPVDGQAWTSEPFTATIRGDKLYGRGACDMKGFIACALTLLPKAVKLSSSGQLSRPLHL
ALSFDEEVGCLGAPLILADLKARGITPDYCIVGEPTNMAMVVAHKGIAVYRCRVHGKSAHSSLTATGVNAISYASRLIGY
VDTLAEEISHRDDNDALFDVPYSTLSVGTIQGGTATNIVPNLCEFTFDYRNLPHMTQDDILLPIQAKVAELSAQMQARAA
DTGIELTQEESVPAMTDNDSAELQALIAALTGDTQRHKVAYATEGGQFTNSGIPTIICGPGSIEQAHKADEYVKLNEIER
CDSFLQRLLESCTMDK
>Mature_415_residues
TVSTRTDGLSHAVMDTDYPSNSIDWLTRLIAFDTVSRHSNLALIEDVQRYCEQLGLSVDLTFNDAKNKANLFVTVAAGGN
ANSSADIINHGLVLSGHTDVVPVDGQAWTSEPFTATIRGDKLYGRGACDMKGFIACALTLLPKAVKLSSSGQLSRPLHLA
LSFDEEVGCLGAPLILADLKARGITPDYCIVGEPTNMAMVVAHKGIAVYRCRVHGKSAHSSLTATGVNAISYASRLIGYV
DTLAEEISHRDDNDALFDVPYSTLSVGTIQGGTATNIVPNLCEFTFDYRNLPHMTQDDILLPIQAKVAELSAQMQARAAD
TGIELTQEESVPAMTDNDSAELQALIAALTGDTQRHKVAYATEGGQFTNSGIPTIICGPGSIEQAHKADEYVKLNEIERC
DSFLQRLLESCTMDK

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=374, Percent_Identity=34.2245989304813, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1788816, Length=236, Percent_Identity=28.8135593220339, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24649206, Length=257, Percent_Identity=29.5719844357977, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24649202, Length=369, Percent_Identity=27.10027100271, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24649204, Length=369, Percent_Identity=27.10027100271, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24649212, Length=398, Percent_Identity=26.1306532663317, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 44714; Mature: 44583

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSTRTDGLSHAVMDTDYPSNSIDWLTRLIAFDTVSRHSNLALIEDVQRYCEQLGLSVD
CCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEE
LTFNDAKNKANLFVTVAAGGNANSSADIINHGLVLSGHTDVVPVDGQAWTSEPFTATIRG
EEECCCCCCCEEEEEEEECCCCCCCHHHHHCCEEEECCCCEEECCCCCCCCCCCEEEEEC
DKLYGRGACDMKGFIACALTLLPKAVKLSSSGQLSRPLHLALSFDEEVGCLGAPLILADL
CEEECCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEEECCCCCCCCCCCHHEEHH
KARGITPDYCIVGEPTNMAMVVAHKGIAVYRCRVHGKSAHSSLTATGVNAISYASRLIGY
HHCCCCCCEEEEECCCCEEEEEEECCEEEEEEEECCCCCCCCEEHHCCHHHHHHHHHHHH
VDTLAEEISHRDDNDALFDVPYSTLSVGTIQGGTATNIVPNLCEFTFDYRNLPHMTQDDI
HHHHHHHHHCCCCCCCEEECCCCCEEEEEECCCCHHHHHHHHHHHEECCCCCCCCCCCCE
LLPIQAKVAELSAQMQARAADTGIELTQEESVPAMTDNDSAELQALIAALTGDTQRHKVA
EEEHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEE
YATEGGQFTNSGIPTIICGPGSIEQAHKADEYVKLNEIERCDSFLQRLLESCTMDK
EEECCCCEECCCCCEEEECCCCCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TVSTRTDGLSHAVMDTDYPSNSIDWLTRLIAFDTVSRHSNLALIEDVQRYCEQLGLSVD
CCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEE
LTFNDAKNKANLFVTVAAGGNANSSADIINHGLVLSGHTDVVPVDGQAWTSEPFTATIRG
EEECCCCCCCEEEEEEEECCCCCCCHHHHHCCEEEECCCCEEECCCCCCCCCCCEEEEEC
DKLYGRGACDMKGFIACALTLLPKAVKLSSSGQLSRPLHLALSFDEEVGCLGAPLILADL
CEEECCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEEECCCCCCCCCCCHHEEHH
KARGITPDYCIVGEPTNMAMVVAHKGIAVYRCRVHGKSAHSSLTATGVNAISYASRLIGY
HHCCCCCCEEEEECCCCEEEEEEECCEEEEEEEECCCCCCCCEEHHCCHHHHHHHHHHHH
VDTLAEEISHRDDNDALFDVPYSTLSVGTIQGGTATNIVPNLCEFTFDYRNLPHMTQDDI
HHHHHHHHHCCCCCCCEEECCCCCEEEEEECCCCHHHHHHHHHHHEECCCCCCCCCCCCE
LLPIQAKVAELSAQMQARAADTGIELTQEESVPAMTDNDSAELQALIAALTGDTQRHKVA
EEEHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEE
YATEGGQFTNSGIPTIICGPGSIEQAHKADEYVKLNEIERCDSFLQRLLESCTMDK
EEECCCCEECCCCCEEEECCCCCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA