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The map label for this gene is kdsA [H]

Identifier: 93006698

GI number: 93006698

Start: 2313950

End: 2314825

Strand: Reverse

Name: kdsA [H]

Synonym: Pcryo_1874

Alternate gene names: 93006698

Gene position: 2314825-2313950 (Counterclockwise)

Preceding gene: 93006699

Following gene: 93006697

Centisome position: 75.65

GC content: 44.98

Gene sequence:

>876_bases
ATGGAAAACCTACTAACCGCGCAGTCGCATATTCAACTTAATACACCTGATAATAAAAACATCAGTATCGGTAATGATCA
GCCATTTGTCTTATTTGGTGGCATGAATGTTTTAGAGTCTAAAGAGATGGCATTTGAGATCGCTGAGCAGTATGTTGATA
TTTGCCAGCGTTTGGGTATCGGCTATGTGTTTAAAGCCAGTTTTGATAAGGCCAATCGCTCAAGTTTGACCTCGTATCGT
GGTCCGGGGCTAGAGAAAGGTATCGATTGGCTTGGGCAAATCAAAGAAAAATTCCAAGTACCGATTATTACGGATGTCCA
CGAACCTTATCAAGCGGCACCAGTCGCTGAAGTAGCTGATATTATCCAGTTGCCTGCGTTTTTATCCCGTCAGACGGATT
TAGTACATGCGATGGCGAAGACGGATGCGATTATTAATATTAAAAAAGCGCAGTTTTTAGCCCCACATGAGATGCGTCAT
ATCGTCAATAAATGTCTTGAGGGCGGTAACGATAAGCTTATCCTGTGTGAGCGCGGTAGTGCCTTTGGTTATAATAACCT
AGTGGTTGATATGCTGGGTTTTGATACCATGAAGCAGATGGAGATACCAGTGTTCTTTGATGTGACGCATAGTTTGCAGC
AGCCAGGCGGCCGTAGTGATAGTGCAGGTGGTCGCCGTGAGCAGATCACCACGCTGGCACGTGCTGGCATGGCAACAGGG
ATTGCAGGATTGTTTTTAGAGGCGCATCCAAATCCAGAAGTGGCAAAATGTGATGGTCCTTGTGCGCTACGTATGAGCCA
ATTAGAGCCTTTCTTACGCCAGCTTAAACAGCTTGATGACTTGGTCAAAGGCTTTGAGACCTTGGATACTCATTAA

Upstream 100 bases:

>100_bases
CTGATTTTTCTAATGGTTTGCCGCTAATTACGCTTATAGCCTTTTTTTAATTGACCTATCGGTTACAATAAGAGATAACA
ATAAAGAGGATACCTACTCA

Downstream 100 bases:

>100_bases
TATCATAAGTAATGTGAGGATAAGACAGTGGCGATTAAAGTGGCACAAGTAAGCATTGAAAATATCAATGATTCAGAAGG
TTTAGATAGCGTCATGACCG

Product: 2-dehydro-3-deoxyphosphooctonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MENLLTAQSHIQLNTPDNKNISIGNDQPFVLFGGMNVLESKEMAFEIAEQYVDICQRLGIGYVFKASFDKANRSSLTSYR
GPGLEKGIDWLGQIKEKFQVPIITDVHEPYQAAPVAEVADIIQLPAFLSRQTDLVHAMAKTDAIINIKKAQFLAPHEMRH
IVNKCLEGGNDKLILCERGSAFGYNNLVVDMLGFDTMKQMEIPVFFDVTHSLQQPGGRSDSAGGRREQITTLARAGMATG
IAGLFLEAHPNPEVAKCDGPCALRMSQLEPFLRQLKQLDDLVKGFETLDTH

Sequences:

>Translated_291_residues
MENLLTAQSHIQLNTPDNKNISIGNDQPFVLFGGMNVLESKEMAFEIAEQYVDICQRLGIGYVFKASFDKANRSSLTSYR
GPGLEKGIDWLGQIKEKFQVPIITDVHEPYQAAPVAEVADIIQLPAFLSRQTDLVHAMAKTDAIINIKKAQFLAPHEMRH
IVNKCLEGGNDKLILCERGSAFGYNNLVVDMLGFDTMKQMEIPVFFDVTHSLQQPGGRSDSAGGRREQITTLARAGMATG
IAGLFLEAHPNPEVAKCDGPCALRMSQLEPFLRQLKQLDDLVKGFETLDTH
>Mature_291_residues
MENLLTAQSHIQLNTPDNKNISIGNDQPFVLFGGMNVLESKEMAFEIAEQYVDICQRLGIGYVFKASFDKANRSSLTSYR
GPGLEKGIDWLGQIKEKFQVPIITDVHEPYQAAPVAEVADIIQLPAFLSRQTDLVHAMAKTDAIINIKKAQFLAPHEMRH
IVNKCLEGGNDKLILCERGSAFGYNNLVVDMLGFDTMKQMEIPVFFDVTHSLQQPGGRSDSAGGRREQITTLARAGMATG
IAGLFLEAHPNPEVAKCDGPCALRMSQLEPFLRQLKQLDDLVKGFETLDTH

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2877

COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsA family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=273, Percent_Identity=65.2014652014652, Blast_Score=372, Evalue=1e-104,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006269 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.55 [H]

Molecular weight: Translated: 32218; Mature: 32218

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENLLTAQSHIQLNTPDNKNISIGNDQPFVLFGGMNVLESKEMAFEIAEQYVDICQRLGI
CCCCCCCCCEEEEECCCCCCEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
GYVFKASFDKANRSSLTSYRGPGLEKGIDWLGQIKEKFQVPIITDVHEPYQAAPVAEVAD
CEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCHHCCCHHHHHH
IIQLPAFLSRQTDLVHAMAKTDAIINIKKAQFLAPHEMRHIVNKCLEGGNDKLILCERGS
HHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCC
AFGYNNLVVDMLGFDTMKQMEIPVFFDVTHSLQQPGGRSDSAGGRREQITTLARAGMATG
CCCCCHHHHHHHCCCHHHHCCCCEEEECHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
IAGLFLEAHPNPEVAKCDGPCALRMSQLEPFLRQLKQLDDLVKGFETLDTH
HHHHEEECCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MENLLTAQSHIQLNTPDNKNISIGNDQPFVLFGGMNVLESKEMAFEIAEQYVDICQRLGI
CCCCCCCCCEEEEECCCCCCEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
GYVFKASFDKANRSSLTSYRGPGLEKGIDWLGQIKEKFQVPIITDVHEPYQAAPVAEVAD
CEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCHHCCCHHHHHH
IIQLPAFLSRQTDLVHAMAKTDAIINIKKAQFLAPHEMRHIVNKCLEGGNDKLILCERGS
HHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCC
AFGYNNLVVDMLGFDTMKQMEIPVFFDVTHSLQQPGGRSDSAGGRREQITTLARAGMATG
CCCCCHHHHHHHCCCHHHHCCCCEEEECHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
IAGLFLEAHPNPEVAKCDGPCALRMSQLEPFLRQLKQLDDLVKGFETLDTH
HHHHEEECCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA