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The map label for this gene is yhdH [H]

Identifier: 93006608

GI number: 93006608

Start: 2208148

End: 2209128

Strand: Reverse

Name: yhdH [H]

Synonym: Pcryo_1784

Alternate gene names: 93006608

Gene position: 2209128-2208148 (Counterclockwise)

Preceding gene: 93006614

Following gene: 93006607

Centisome position: 72.2

GC content: 41.59

Gene sequence:

>981_bases
ATGAAAGCCTTTGTAGTAGAGAAAGTAGCGGACAGAGCGTTTTCTTGCGCAATACAAGAAGTTCCTGTACCAGAATGTGA
TAAAGATGAAGTGGTCATAAAGACAACTTATTCATCATTAAATTATAAGGATGCTTTAAGCTCTGTCGGCAATCCGGGTG
TGACTAGAAAGTTCCCGCATATCACCGGTATCGATGTAGCCGGAGTGGTACACCAAACGACATCTGATGCCTTTGCAGTC
GGAGAAAAAGTATTGGTGACTGGCTATGACTTAGGGATGAATACTGATGGCGGTCATGCAGAGTTTGTCAAAGTGCCAGC
GTCATGGGTTGCTCTTATTCCTGACACAATAACTGATAAAGAAATCATGACTTTCGGTACTGCAGGATTAACGGCAGCTT
TGAGTGTTAATGAATTATTAGATAACGGTGTCAAGCCAGAAGATGGTGAGGTTTTAGTCACTGGTGCTACTGGTGGCGTG
GGTTCTTTAGCGGTTTCTATCCTAAATAAAATTGGCTTTACTGTCGTTGCCGTATCAGGAAAAGAGGAACAAATTGATTA
TCTCAAACAAATTGGCGCGTCAGAAGTCATCCTTAGAGATACTTTCAATGAGGATGCTAAAAAACCCATTATGGCTGAAA
GATATGCAGGGGTTGTCGATACGGTTGGCGGTGATATTCTAGCCAATGCCCTAAAATATATAAAATACGATGGGGTTGCT
ACTTGTTGTGGGTTAACAGCGTCACATGAACTCAATACCAATGTATTCCCATTTATTTTAAGGGGCGTCAGACTCATAGG
TATCGACTCGGTTGAATGTAAACTTGAGAAGAAACAAGCGGCATGGGACAAACTGGCTGGTGAGTTTAAAATAGCTACTT
TAGATAGTATCACTAACGAGATTGGCCTAGAAGATATCAAAGACACCTACGCATCGATGTTAGAGGGAAAATCAGTGGGC
AGGTATGTGGTAAAAATATAA

Upstream 100 bases:

>100_bases
TGGTGAAATGCTAACTTCTAATTTAAGTGATTAAAGGCGAACAATCCTCTCGTTACAAATATTGAGGTTTTGTAGTCCTA
AGAATATATAAGGAATGAAT

Downstream 100 bases:

>100_bases
AGGACATCTATTTTCTTGTCGATATGATATGTAGTAAGAAACTCTTAATTTTAAAAAATTAAGAGTTTCTTAGTTTCTAT
AGATAAAGTTTTATCGAATA

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKAFVVEKVADRAFSCAIQEVPVPECDKDEVVIKTTYSSLNYKDALSSVGNPGVTRKFPHITGIDVAGVVHQTTSDAFAV
GEKVLVTGYDLGMNTDGGHAEFVKVPASWVALIPDTITDKEIMTFGTAGLTAALSVNELLDNGVKPEDGEVLVTGATGGV
GSLAVSILNKIGFTVVAVSGKEEQIDYLKQIGASEVILRDTFNEDAKKPIMAERYAGVVDTVGGDILANALKYIKYDGVA
TCCGLTASHELNTNVFPFILRGVRLIGIDSVECKLEKKQAAWDKLAGEFKIATLDSITNEIGLEDIKDTYASMLEGKSVG
RYVVKI

Sequences:

>Translated_326_residues
MKAFVVEKVADRAFSCAIQEVPVPECDKDEVVIKTTYSSLNYKDALSSVGNPGVTRKFPHITGIDVAGVVHQTTSDAFAV
GEKVLVTGYDLGMNTDGGHAEFVKVPASWVALIPDTITDKEIMTFGTAGLTAALSVNELLDNGVKPEDGEVLVTGATGGV
GSLAVSILNKIGFTVVAVSGKEEQIDYLKQIGASEVILRDTFNEDAKKPIMAERYAGVVDTVGGDILANALKYIKYDGVA
TCCGLTASHELNTNVFPFILRGVRLIGIDSVECKLEKKQAAWDKLAGEFKIATLDSITNEIGLEDIKDTYASMLEGKSVG
RYVVKI
>Mature_326_residues
MKAFVVEKVADRAFSCAIQEVPVPECDKDEVVIKTTYSSLNYKDALSSVGNPGVTRKFPHITGIDVAGVVHQTTSDAFAV
GEKVLVTGYDLGMNTDGGHAEFVKVPASWVALIPDTITDKEIMTFGTAGLTAALSVNELLDNGVKPEDGEVLVTGATGGV
GSLAVSILNKIGFTVVAVSGKEEQIDYLKQIGASEVILRDTFNEDAKKPIMAERYAGVVDTVGGDILANALKYIKYDGVA
TCCGLTASHELNTNVFPFILRGVRLIGIDSVECKLEKKQAAWDKLAGEFKIATLDSITNEIGLEDIKDTYASMLEGKSVG
RYVVKI

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789651, Length=328, Percent_Identity=40.5487804878049, Blast_Score=249, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6319621, Length=335, Percent_Identity=24.1791044776119, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=334, Percent_Identity=22.1556886227545, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6323729, Length=334, Percent_Identity=24.8502994011976, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323961, Length=334, Percent_Identity=21.8562874251497, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR014188 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 34760; Mature: 34760

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFVVEKVADRAFSCAIQEVPVPECDKDEVVIKTTYSSLNYKDALSSVGNPGVTRKFPH
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCC
ITGIDVAGVVHQTTSDAFAVGEKVLVTGYDLGMNTDGGHAEFVKVPASWVALIPDTITDK
CCCCCHHHHHHHCCCCHHHCCCEEEEEEEECCCCCCCCCEEEEECCCHHHEECCCCCCCC
EIMTFGTAGLTAALSVNELLDNGVKPEDGEVLVTGATGGVGSLAVSILNKIGFTVVAVSG
HHEEECCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCEEEEEECC
KEEQIDYLKQIGASEVILRDTFNEDAKKPIMAERYAGVVDTVGGDILANALKYIKYDGVA
CHHHHHHHHHCCCCCEEEECCCCCHHCCCHHHHHHCCHHHHCCHHHHHHHHHHHHCCCHH
TCCGLTASHELNTNVFPFILRGVRLIGIDSVECKLEKKQAAWDKLAGEFKIATLDSITNE
HHHCCCCCCCCCCCHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHH
IGLEDIKDTYASMLEGKSVGRYVVKI
CCHHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MKAFVVEKVADRAFSCAIQEVPVPECDKDEVVIKTTYSSLNYKDALSSVGNPGVTRKFPH
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCC
ITGIDVAGVVHQTTSDAFAVGEKVLVTGYDLGMNTDGGHAEFVKVPASWVALIPDTITDK
CCCCCHHHHHHHCCCCHHHCCCEEEEEEEECCCCCCCCCEEEEECCCHHHEECCCCCCCC
EIMTFGTAGLTAALSVNELLDNGVKPEDGEVLVTGATGGVGSLAVSILNKIGFTVVAVSG
HHEEECCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCEEEEEECC
KEEQIDYLKQIGASEVILRDTFNEDAKKPIMAERYAGVVDTVGGDILANALKYIKYDGVA
CHHHHHHHHHCCCCCEEEECCCCCHHCCCHHHHHHCCHHHHCCHHHHHHHHHHHHCCCHH
TCCGLTASHELNTNVFPFILRGVRLIGIDSVECKLEKKQAAWDKLAGEFKIATLDSITNE
HHHCCCCCCCCCCCHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHH
IGLEDIKDTYASMLEGKSVGRYVVKI
CCHHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1370469; 9278503 [H]