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The map label for this gene is lolA [H]

Identifier: 93006577

GI number: 93006577

Start: 2168727

End: 2169428

Strand: Reverse

Name: lolA [H]

Synonym: Pcryo_1753

Alternate gene names: 93006577

Gene position: 2169428-2168727 (Counterclockwise)

Preceding gene: 93006578

Following gene: 93006568

Centisome position: 70.9

GC content: 43.45

Gene sequence:

>702_bases
ATGACTTTATTAACCAACCAATCAACTAAACAGACAACAACGCTAAAACAAAAGATGATGGGCGGAGCATTGGCAGGCGT
CTTAATGACTACGCTTGGCGTCGCAGCGCCTATGATGGCGATAACGCAATCGGCGATGGCAGCGCCAGCTGACAATATAA
CGGCAGCTAAGCGTTTAAACAAGCTGTTGACCAATACTAAGAGCATGACGGCCAACTTTAGCCAGACGACTAAAGGCGCT
AATAGTGGTACGTTCAGTGGTACCATGAGCGTGCAACGTCCAAATAATTTCCGCTGGGAAACCAAGTCACCGTCAGAACA
GCTGATTGTGGCAAATGGTAGCTCGATGTGGGTTTATGATAAGGACTTGGAGCAAGCCACTAAACAAAACGTAGACAGCC
AAGTGGGTAATACGCCAGCGCTATTACTATCAGGTGATCCAAGTAAAATTGATAAGAACTTTAAAATCACCCAGCCGTAT
GCCAATAAAAACTACTATGTGCTGTATCCAAAGTCAGATAGTGCTAGCTTTAAAAGCTTATCAATGAGCTTTAGCGGTGG
CAAGCCTGTGATGATGGTGTTAAATGATAGCTTAGGACAGACTACTTCTATTAAATTTAGCGGTATCAAAATGAACCCAA
GCATTAGCAGCAATCAGTTTAAGTTTACCCCGCCAAAAGGTGTTGATATTATCAATCAGTAG

Upstream 100 bases:

>100_bases
ACACCGGTTTTGTACTCGTATGATAAACATTTACCGAAAACAAAAATTTGATAAAACGTTTTATTTTTATGCTATTTTGC
ATTTTTAGAGAGGATTTATA

Downstream 100 bases:

>100_bases
AAGTGATCAGCATTTTATTCATTAAGCTAGCTGATTAGAATAATAAAAAAGGACATACCTAATAGGCGTGTCCTTTTTTA
TTGAGCAAGAGTATTTTATC

Product: outer membrane lipoprotein carrier protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MTLLTNQSTKQTTTLKQKMMGGALAGVLMTTLGVAAPMMAITQSAMAAPADNITAAKRLNKLLTNTKSMTANFSQTTKGA
NSGTFSGTMSVQRPNNFRWETKSPSEQLIVANGSSMWVYDKDLEQATKQNVDSQVGNTPALLLSGDPSKIDKNFKITQPY
ANKNYYVLYPKSDSASFKSLSMSFSGGKPVMMVLNDSLGQTTSIKFSGIKMNPSISSNQFKFTPPKGVDIINQ

Sequences:

>Translated_233_residues
MTLLTNQSTKQTTTLKQKMMGGALAGVLMTTLGVAAPMMAITQSAMAAPADNITAAKRLNKLLTNTKSMTANFSQTTKGA
NSGTFSGTMSVQRPNNFRWETKSPSEQLIVANGSSMWVYDKDLEQATKQNVDSQVGNTPALLLSGDPSKIDKNFKITQPY
ANKNYYVLYPKSDSASFKSLSMSFSGGKPVMMVLNDSLGQTTSIKFSGIKMNPSISSNQFKFTPPKGVDIINQ
>Mature_232_residues
TLLTNQSTKQTTTLKQKMMGGALAGVLMTTLGVAAPMMAITQSAMAAPADNITAAKRLNKLLTNTKSMTANFSQTTKGAN
SGTFSGTMSVQRPNNFRWETKSPSEQLIVANGSSMWVYDKDLEQATKQNVDSQVGNTPALLLSGDPSKIDKNFKITQPYA
NKNYYVLYPKSDSASFKSLSMSFSGGKPVMMVLNDSLGQTTSIKFSGIKMNPSISSNQFKFTPPKGVDIINQ

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family [H]

Homologues:

Organism=Escherichia coli, GI145693108, Length=196, Percent_Identity=28.0612244897959, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004564
- InterPro:   IPR018323 [H]

Pfam domain/function: PF03548 LolA [H]

EC number: NA

Molecular weight: Translated: 25136; Mature: 25005

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLTNQSTKQTTTLKQKMMGGALAGVLMTTLGVAAPMMAITQSAMAAPADNITAAKRLN
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KLLTNTKSMTANFSQTTKGANSGTFSGTMSVQRPNNFRWETKSPSEQLIVANGSSMWVYD
HHHHCCHHHCCCCHHHCCCCCCCCCEEEEEEECCCCCEECCCCCCCEEEEECCCEEEEEE
KDLEQATKQNVDSQVGNTPALLLSGDPSKIDKNFKITQPYANKNYYVLYPKSDSASFKSL
CHHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCEEEECCCCCCCEEEEEECCCCCCCEEE
SMSFSGGKPVMMVLNDSLGQTTSIKFSGIKMNPSISSNQFKFTPPKGVDIINQ
EEEECCCCEEEEEEECCCCCEEEEEEEEEEECCCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
TLLTNQSTKQTTTLKQKMMGGALAGVLMTTLGVAAPMMAITQSAMAAPADNITAAKRLN
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
KLLTNTKSMTANFSQTTKGANSGTFSGTMSVQRPNNFRWETKSPSEQLIVANGSSMWVYD
HHHHCCHHHCCCCHHHCCCCCCCCCEEEEEEECCCCCEECCCCCCCEEEEECCCEEEEEE
KDLEQATKQNVDSQVGNTPALLLSGDPSKIDKNFKITQPYANKNYYVLYPKSDSASFKSL
CHHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCEEEECCCCCCCEEEEEECCCCCCCEEE
SMSFSGGKPVMMVLNDSLGQTTSIKFSGIKMNPSISSNQFKFTPPKGVDIINQ
EEEECCCCEEEEEEECCCCCEEEEEEEEEEECCCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA