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The map label for this gene is pknB [H]

Identifier: 93006542

GI number: 93006542

Start: 2127569

End: 2128591

Strand: Reverse

Name: pknB [H]

Synonym: Pcryo_1718

Alternate gene names: 93006542

Gene position: 2128591-2127569 (Counterclockwise)

Preceding gene: 93006544

Following gene: 93006539

Centisome position: 69.56

GC content: 40.18

Gene sequence:

>1023_bases
ATGAAAAATAGTGCCAGTATTCCTTGTGTATTACAAGCAGATGCAAAACAAGCGTTACGAGTGCAAGCGCAGCAAATCCT
GCCAGCATTAACGGCATTCTTTTTCAGCCTAAATTATAGCGAGATCTCGCATCAACGACTCAGTCAGCAACATAATGGTA
GTGACCTTGACTATCAGGGCTTAACACGCGCCCAACACTCGCAGTTTGGGAATGTGATGATTAAATGGCAGTTATATGCT
AATGCTAATCAAGACCTGTCTGATTTAACCTATGAAGCTGACGTTCTAACATCTATAAACAACTTATCAAATAATCAAAA
CAAGCTTCAAAATAGCCTTTCCGCTATCGTACCACCACTATTGTTTTATGAAAATATTACTTCGGAAATATTAACGCAGC
TGCAGCAGCTGACTATCCTGGTCATGCCTTATTATCCAAATGGCAGCTTGGCAAATCAGCTGAGTGCTCAAAAGCATTTC
TTATTAACACAGGCACAAAAGAATCAATTTATCCTACAATCTGCTAATCTTATTTACCGCTTACATAATATCGGCTGGCT
ACATAATGATATTAAGCCCAGTAATATTTTGCTAGAAGGTTTTTTGCCAAATAATGCGGATAATAGCCGTATCACCTTTG
ATTTATTATTGACGGATTTTACTTTAACGAGCACTCTTTATCAGCCAAGTGTGGCAAATATTGCTGGCACGCCTGCCTAT
CTTGCTCCTGAGCGTTGGCAAGGGTATGGCTCAACGGTTCAAAGCGATATATACGCTTTTGGGATTATGTTGTATGAGAT
ATTAGTCGGCGAGCGACCATTTGCCGTTGATGTTCGAAGTAGTGATTCAATGATTGATTGGGCGACACAACATTGCCAAA
AGTCTGTTCCGACCTTGCCATTAGAATATAGTCGCTATCAGGACGTTGTTGATAAGGCATTGGCGAAGCAGATAGAGAAA
AGGTATCAGAGTATGGGTGAGATGCTTTTAGATTTAGAAAGTATGGAATGGCAAGGTAACTGA

Upstream 100 bases:

>100_bases
AATTCATAACGGGCTTAGTAGATTGAGGCATAATACTCAGTCGCTTATAAAAATTAAAATGACGTTTGGCTTAATAGATA
TATAAAGGCATCACTTTACC

Downstream 100 bases:

>100_bases
GCCCAACAACTAAGGTTGAAAGGATAAATCCAGTAAATCCCAGACACAAAAAAACCTGCTAAAAAGCAGGCTTTAATATT
TGGTCTAAGATGTACTATCC

Product: serine/threonine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKNSASIPCVLQADAKQALRVQAQQILPALTAFFFSLNYSEISHQRLSQQHNGSDLDYQGLTRAQHSQFGNVMIKWQLYA
NANQDLSDLTYEADVLTSINNLSNNQNKLQNSLSAIVPPLLFYENITSEILTQLQQLTILVMPYYPNGSLANQLSAQKHF
LLTQAQKNQFILQSANLIYRLHNIGWLHNDIKPSNILLEGFLPNNADNSRITFDLLLTDFTLTSTLYQPSVANIAGTPAY
LAPERWQGYGSTVQSDIYAFGIMLYEILVGERPFAVDVRSSDSMIDWATQHCQKSVPTLPLEYSRYQDVVDKALAKQIEK
RYQSMGEMLLDLESMEWQGN

Sequences:

>Translated_340_residues
MKNSASIPCVLQADAKQALRVQAQQILPALTAFFFSLNYSEISHQRLSQQHNGSDLDYQGLTRAQHSQFGNVMIKWQLYA
NANQDLSDLTYEADVLTSINNLSNNQNKLQNSLSAIVPPLLFYENITSEILTQLQQLTILVMPYYPNGSLANQLSAQKHF
LLTQAQKNQFILQSANLIYRLHNIGWLHNDIKPSNILLEGFLPNNADNSRITFDLLLTDFTLTSTLYQPSVANIAGTPAY
LAPERWQGYGSTVQSDIYAFGIMLYEILVGERPFAVDVRSSDSMIDWATQHCQKSVPTLPLEYSRYQDVVDKALAKQIEK
RYQSMGEMLLDLESMEWQGN
>Mature_340_residues
MKNSASIPCVLQADAKQALRVQAQQILPALTAFFFSLNYSEISHQRLSQQHNGSDLDYQGLTRAQHSQFGNVMIKWQLYA
NANQDLSDLTYEADVLTSINNLSNNQNKLQNSLSAIVPPLLFYENITSEILTQLQQLTILVMPYYPNGSLANQLSAQKHF
LLTQAQKNQFILQSANLIYRLHNIGWLHNDIKPSNILLEGFLPNNADNSRITFDLLLTDFTLTSTLYQPSVANIAGTPAY
LAPERWQGYGSTVQSDIYAFGIMLYEILVGERPFAVDVRSSDSMIDWATQHCQKSVPTLPLEYSRYQDVVDKALAKQIEK
RYQSMGEMLLDLESMEWQGN

Specific function: Unknown

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI23943882, Length=139, Percent_Identity=34.5323741007194, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI217330559, Length=217, Percent_Identity=29.9539170506912, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI217330557, Length=217, Percent_Identity=29.9539170506912, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI4507831, Length=208, Percent_Identity=29.3269230769231, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI30039692, Length=154, Percent_Identity=29.8701298701299, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI156766068, Length=204, Percent_Identity=31.3725490196078, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17557200, Length=162, Percent_Identity=30.2469135802469, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508247, Length=183, Percent_Identity=24.5901639344262, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6320042, Length=208, Percent_Identity=28.3653846153846, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323643, Length=144, Percent_Identity=32.6388888888889, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24648518, Length=138, Percent_Identity=32.6086956521739, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI281366161, Length=157, Percent_Identity=30.5732484076433, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24663470, Length=157, Percent_Identity=30.5732484076433, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007536, Length=156, Percent_Identity=31.4102564102564, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI116007530, Length=156, Percent_Identity=31.4102564102564, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI116007532, Length=156, Percent_Identity=31.4102564102564, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI116007534, Length=156, Percent_Identity=31.4102564102564, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR005543
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271 [H]

Pfam domain/function: PF03793 PASTA; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 38480; Mature: 38480

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSASIPCVLQADAKQALRVQAQQILPALTAFFFSLNYSEISHQRLSQQHNGSDLDYQG
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHH
LTRAQHSQFGNVMIKWQLYANANQDLSDLTYEADVLTSINNLSNNQNKLQNSLSAIVPPL
HHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LFYENITSEILTQLQQLTILVMPYYPNGSLANQLSAQKHFLLTQAQKNQFILQSANLIYR
HHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHH
LHNIGWLHNDIKPSNILLEGFLPNNADNSRITFDLLLTDFTLTSTLYQPSVANIAGTPAY
HHHCCHHCCCCCCCCEEEEECCCCCCCCCEEEEEEEEHHHHHHHHHCCCCHHHCCCCCCC
LAPERWQGYGSTVQSDIYAFGIMLYEILVGERPFAVDVRSSDSMIDWATQHCQKSVPTLP
CCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCC
LEYSRYQDVVDKALAKQIEKRYQSMGEMLLDLESMEWQGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKNSASIPCVLQADAKQALRVQAQQILPALTAFFFSLNYSEISHQRLSQQHNGSDLDYQG
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHH
LTRAQHSQFGNVMIKWQLYANANQDLSDLTYEADVLTSINNLSNNQNKLQNSLSAIVPPL
HHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LFYENITSEILTQLQQLTILVMPYYPNGSLANQLSAQKHFLLTQAQKNQFILQSANLIYR
HHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHH
LHNIGWLHNDIKPSNILLEGFLPNNADNSRITFDLLLTDFTLTSTLYQPSVANIAGTPAY
HHHCCHHCCCCCCCCEEEEECCCCCCCCCEEEEEEEEHHHHHHHHHCCCCHHHCCCCCCC
LAPERWQGYGSTVQSDIYAFGIMLYEILVGERPFAVDVRSSDSMIDWATQHCQKSVPTLP
CCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCC
LEYSRYQDVVDKALAKQIEKRYQSMGEMLLDLESMEWQGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]