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The map label for this gene is gap [H]

Identifier: 93006508

GI number: 93006508

Start: 2072740

End: 2074185

Strand: Reverse

Name: gap [H]

Synonym: Pcryo_1684

Alternate gene names: 93006508

Gene position: 2074185-2072740 (Counterclockwise)

Preceding gene: 93006509

Following gene: 93006507

Centisome position: 67.79

GC content: 43.5

Gene sequence:

>1446_bases
ATGTTTCTCGTGAGTAACGCTGATACCTTACGCCAATTACATCAAGACCATTTGAGCAACTATAACACCCAGGAGCAACA
AGCGATTGAGCTCATGGGGCTATTGAACAAGCTCTACAATGAGCAAGATGTGCAAGTGACTTTATTCGGTGATACGCTAG
ATAGCAATTCTGTGGGTCAAATATTGGCGCTGCATCAAAAAGTTGCTTTGCGTGATCAAGGTGCTCATGCGATTGATATC
GCTGATACTTTAGCGATGGTTAAAGTGTTAGCAGAGAATAAAAATCTGTCAGCTGTACGTATTGATGTTGGTCAGCTAAT
CGCTAATGACAGTGATATTCAATCGGCATTACAGTCTGTTGATAATACTAAAGCGGCTATCAATGGCGCAGCGGATGTGG
TGCTATATGGTTTTGGTCGTATTGGTCGTATTCTAACTCGTTTATTGTTATCGCAAGCGTCAAGTGCCAAGGGCATGCAG
CTAAAAGCCATCGTAGTACGTCCCGCAGCAGCAGGCGACTTGGCTAAGCGTGCGTCATTGCTAGAGCGCGATTCGATTCA
CGGTAGTTTTGCAGGCGGCGTGATTGTTGATGATGAAAACAATGGTTTGATCATTAATGGTCGCTTTGTGCAAGTTATCT
ATGCCAAAGACCCAAGCGAGATTGATTATACTGCTTATGGTATTAACGATGCACTGGTCATTGATAATACGGGTATCTGG
AAAGATGAGGCTGGTCTTGGTAAGCATTTACAATCGACTGGTGTGAAAAAAGTGCTATTAACGGCACCTGCTGGCGGCGA
GATTAAAAACGTCGTATATGGCGTAAATAACGATACGGTCGGCGATGACACTATCGTTAGTGCGGCGAGCTGTACGACCA
ACGCAATTACCCCAACATTAAAAGTATTAAATGACGCATACGGTATTGAAAATGGTCACGTTGAAACCATTCACTCGTTC
ACTAACGATCAGAACTTAATTGATAATTATCATAAAGCAGATCGCCGTGGTCGTAGTGCGGTATTGAACATGGTTATCAC
CAGTACTGGTGCAGCAAAGGCAGTCGGGAAAGCGCTACCAGAGCTGAGTGGTAAATTGACGGGCAATGCCATCCGTGTAC
CGACACCAAACGTTAGCTTAGCGATTTTGAATTTAAATCTTAAAACTGCGCCAGCTAGTGCTGATGCGTTAAATGAGTTT
ATGCGCAAAATTTCAAATAGTAGCCAGTGGCAAACACAAATTGCTTACACGGATTCTACAGAAGCGGTATCAACGGATTT
TGTCGGTGATACACATGTAGGTATCGTTGATGCCCAAGCGACTATTTTGACGGATAATCATGCTATCGTTTATATTTGGT
ATGACAACGAAGTTGGTTATAGCACGCAAGTATTACGTTTGGCAACGCAAATGGCAGGTATCAGCTATGCGCAGATTCCA
GCTTAA

Upstream 100 bases:

>100_bases
AGTCGTCTGTTAGCATATCTGAGTGAGTACATAGACTGTATATACCTTATTCAATAATATTTCTTCCTATTTTACTGATT
CCCCAATACTGACCATAAGG

Downstream 100 bases:

>100_bases
TACGTTTGTATAGCAGCAATGACTCGGTCATAATGCTTTGATTCAAAGAGCAGAGCGATGGTCATTAGTTATATAAACAA
ACGGATATGGTTTTAGCGGT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MFLVSNADTLRQLHQDHLSNYNTQEQQAIELMGLLNKLYNEQDVQVTLFGDTLDSNSVGQILALHQKVALRDQGAHAIDI
ADTLAMVKVLAENKNLSAVRIDVGQLIANDSDIQSALQSVDNTKAAINGAADVVLYGFGRIGRILTRLLLSQASSAKGMQ
LKAIVVRPAAAGDLAKRASLLERDSIHGSFAGGVIVDDENNGLIINGRFVQVIYAKDPSEIDYTAYGINDALVIDNTGIW
KDEAGLGKHLQSTGVKKVLLTAPAGGEIKNVVYGVNNDTVGDDTIVSAASCTTNAITPTLKVLNDAYGIENGHVETIHSF
TNDQNLIDNYHKADRRGRSAVLNMVITSTGAAKAVGKALPELSGKLTGNAIRVPTPNVSLAILNLNLKTAPASADALNEF
MRKISNSSQWQTQIAYTDSTEAVSTDFVGDTHVGIVDAQATILTDNHAIVYIWYDNEVGYSTQVLRLATQMAGISYAQIP
A

Sequences:

>Translated_481_residues
MFLVSNADTLRQLHQDHLSNYNTQEQQAIELMGLLNKLYNEQDVQVTLFGDTLDSNSVGQILALHQKVALRDQGAHAIDI
ADTLAMVKVLAENKNLSAVRIDVGQLIANDSDIQSALQSVDNTKAAINGAADVVLYGFGRIGRILTRLLLSQASSAKGMQ
LKAIVVRPAAAGDLAKRASLLERDSIHGSFAGGVIVDDENNGLIINGRFVQVIYAKDPSEIDYTAYGINDALVIDNTGIW
KDEAGLGKHLQSTGVKKVLLTAPAGGEIKNVVYGVNNDTVGDDTIVSAASCTTNAITPTLKVLNDAYGIENGHVETIHSF
TNDQNLIDNYHKADRRGRSAVLNMVITSTGAAKAVGKALPELSGKLTGNAIRVPTPNVSLAILNLNLKTAPASADALNEF
MRKISNSSQWQTQIAYTDSTEAVSTDFVGDTHVGIVDAQATILTDNHAIVYIWYDNEVGYSTQVLRLATQMAGISYAQIP
A
>Mature_481_residues
MFLVSNADTLRQLHQDHLSNYNTQEQQAIELMGLLNKLYNEQDVQVTLFGDTLDSNSVGQILALHQKVALRDQGAHAIDI
ADTLAMVKVLAENKNLSAVRIDVGQLIANDSDIQSALQSVDNTKAAINGAADVVLYGFGRIGRILTRLLLSQASSAKGMQ
LKAIVVRPAAAGDLAKRASLLERDSIHGSFAGGVIVDDENNGLIINGRFVQVIYAKDPSEIDYTAYGINDALVIDNTGIW
KDEAGLGKHLQSTGVKKVLLTAPAGGEIKNVVYGVNNDTVGDDTIVSAASCTTNAITPTLKVLNDAYGIENGHVETIHSF
TNDQNLIDNYHKADRRGRSAVLNMVITSTGAAKAVGKALPELSGKLTGNAIRVPTPNVSLAILNLNLKTAPASADALNEF
MRKISNSSQWQTQIAYTDSTEAVSTDFVGDTHVGIVDAQATILTDNHAIVYIWYDNEVGYSTQVLRLATQMAGISYAQIP
A

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=347, Percent_Identity=38.6167146974063, Blast_Score=202, Evalue=8e-52,
Organism=Homo sapiens, GI7657116, Length=339, Percent_Identity=39.8230088495575, Blast_Score=198, Evalue=1e-50,
Organism=Escherichia coli, GI1788079, Length=338, Percent_Identity=39.3491124260355, Blast_Score=204, Evalue=9e-54,
Organism=Escherichia coli, GI1789295, Length=347, Percent_Identity=34.2939481268012, Blast_Score=178, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17534677, Length=350, Percent_Identity=39.4285714285714, Blast_Score=192, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17534679, Length=350, Percent_Identity=38.8571428571429, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17568413, Length=346, Percent_Identity=38.150289017341, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI32566163, Length=346, Percent_Identity=38.150289017341, Blast_Score=189, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6321631, Length=344, Percent_Identity=39.5348837209302, Blast_Score=209, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6322409, Length=343, Percent_Identity=40.8163265306122, Blast_Score=207, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6322468, Length=343, Percent_Identity=39.6501457725948, Blast_Score=206, Evalue=7e-54,
Organism=Drosophila melanogaster, GI85725000, Length=340, Percent_Identity=38.2352941176471, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI22023983, Length=340, Percent_Identity=38.2352941176471, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI17933600, Length=338, Percent_Identity=38.4615384615385, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI18110149, Length=338, Percent_Identity=38.4615384615385, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI19922412, Length=346, Percent_Identity=38.4393063583815, Blast_Score=191, Evalue=1e-48,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 51451; Mature: 51451

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLVSNADTLRQLHQDHLSNYNTQEQQAIELMGLLNKLYNEQDVQVTLFGDTLDSNSVGQ
CEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHH
ILALHQKVALRDQGAHAIDIADTLAMVKVLAENKNLSAVRIDVGQLIANDSDIQSALQSV
HHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCCHHHHHHHHHC
DNTKAAINGAADVVLYGFGRIGRILTRLLLSQASSAKGMQLKAIVVRPAAAGDLAKRASL
CCCHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHH
LERDSIHGSFAGGVIVDDENNGLIINGRFVQVIYAKDPSEIDYTAYGINDALVIDNTGIW
HHHHCCCCEEECCEEEECCCCCEEEECEEEEEEEECCCCCCCEEEECCCCEEEEECCCCC
KDEAGLGKHLQSTGVKKVLLTAPAGGEIKNVVYGVNNDTVGDDTIVSAASCTTNAITPTL
CCCCCHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCCCHHEEECCCCCCCCCHHH
KVLNDAYGIENGHVETIHSFTNDQNLIDNYHKADRRGRSAVLNMVITSTGAAKAVGKALP
HHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHEEHEEECCCHHHHHHHHHH
ELSGKLTGNAIRVPTPNVSLAILNLNLKTAPASADALNEFMRKISNSSQWQTQIAYTDST
HHCCCCCCCEEECCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEEECCC
EAVSTDFVGDTHVGIVDAQATILTDNHAIVYIWYDNEVGYSTQVLRLATQMAGISYAQIP
CCCEECCCCCCCEEEEECEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEECCC
A
C
>Mature Secondary Structure
MFLVSNADTLRQLHQDHLSNYNTQEQQAIELMGLLNKLYNEQDVQVTLFGDTLDSNSVGQ
CEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHH
ILALHQKVALRDQGAHAIDIADTLAMVKVLAENKNLSAVRIDVGQLIANDSDIQSALQSV
HHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCCHHHHHHHHHC
DNTKAAINGAADVVLYGFGRIGRILTRLLLSQASSAKGMQLKAIVVRPAAAGDLAKRASL
CCCHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHH
LERDSIHGSFAGGVIVDDENNGLIINGRFVQVIYAKDPSEIDYTAYGINDALVIDNTGIW
HHHHCCCCEEECCEEEECCCCCEEEECEEEEEEEECCCCCCCEEEECCCCEEEEECCCCC
KDEAGLGKHLQSTGVKKVLLTAPAGGEIKNVVYGVNNDTVGDDTIVSAASCTTNAITPTL
CCCCCHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCCCHHEEECCCCCCCCCHHH
KVLNDAYGIENGHVETIHSFTNDQNLIDNYHKADRRGRSAVLNMVITSTGAAKAVGKALP
HHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHEEHEEECCCHHHHHHHHHH
ELSGKLTGNAIRVPTPNVSLAILNLNLKTAPASADALNEFMRKISNSSQWQTQIAYTDST
HHCCCCCCCEEECCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEEECCC
EAVSTDFVGDTHVGIVDAQATILTDNHAIVYIWYDNEVGYSTQVLRLATQMAGISYAQIP
CCCEECCCCCCCEEEEECEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEECCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]