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The map label for this gene is arsC [H]

Identifier: 93006291

GI number: 93006291

Start: 1806411

End: 1806815

Strand: Reverse

Name: arsC [H]

Synonym: Pcryo_1465

Alternate gene names: 93006291

Gene position: 1806815-1806411 (Counterclockwise)

Preceding gene: 93006292

Following gene: 93006290

Centisome position: 59.05

GC content: 45.19

Gene sequence:

>405_bases
ATGACATCTTTGATTTTTCACAACCCAAAATGCGGTACTTCTCGTAATACCTTAGCCATTATGCAAGCGTCAGGGGATAA
TCCAGAGGTGATTGAATACCTTAAAACACCGCCGAGTCGCGAGTATTTGGTTGAGCTGTTGGCAAAAATGGCTCTCTCAC
CACGAGAGCTGTTACGCAGTAAAGAATCGATTAATGATGAGCTGGGTCTAGACAACCCTGCGCTATCTGATGATGAGATT
ATCGATGCCATGATTGACCATCCTATCTTAATCAATCGGCCTATCGTAGTCACAGATAAGGGCGCAGCATTGTGCCGACC
ATCGGAGCGAGTGTTTGAGTTACTGGAGAACCCCGTGAGTAGCTTCACTAAGGAAGATGGGGAAGTGATTTATCATGGCA
AATAA

Upstream 100 bases:

>100_bases
ATTAATGAGCTGGATGATGTTGAAAACCACCCCCATTGTTAAACTGCTATCAATCAAAAACATCCCAATTCTATATTCAT
AAAAAATAGGTGAGATTACG

Downstream 100 bases:

>100_bases
TACAGCAGATTTGAATGTGGTCGATTTAGATAATTTGCCTAATGTTGATTCAAGTCTTATTCATCCTATCGATATTGAGT
CTTTAATAGGCGCAAATGAC

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MTSLIFHNPKCGTSRNTLAIMQASGDNPEVIEYLKTPPSREYLVELLAKMALSPRELLRSKESINDELGLDNPALSDDEI
IDAMIDHPILINRPIVVTDKGAALCRPSERVFELLENPVSSFTKEDGEVIYHGK

Sequences:

>Translated_134_residues
MTSLIFHNPKCGTSRNTLAIMQASGDNPEVIEYLKTPPSREYLVELLAKMALSPRELLRSKESINDELGLDNPALSDDEI
IDAMIDHPILINRPIVVTDKGAALCRPSERVFELLENPVSSFTKEDGEVIYHGK
>Mature_133_residues
TSLIFHNPKCGTSRNTLAIMQASGDNPEVIEYLKTPPSREYLVELLAKMALSPRELLRSKESINDELGLDNPALSDDEII
DAMIDHPILINRPIVVTDKGAALCRPSERVFELLENPVSSFTKEDGEVIYHGK

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=127, Percent_Identity=54.3307086614173, Blast_Score=138, Evalue=2e-34,
Organism=Escherichia coli, GI1788841, Length=112, Percent_Identity=43.75, Blast_Score=98, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 14919; Mature: 14788

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLIFHNPKCGTSRNTLAIMQASGDNPEVIEYLKTPPSREYLVELLAKMALSPRELLRS
CCCCEEECCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHH
KESINDELGLDNPALSDDEIIDAMIDHPILINRPIVVTDKGAALCRPSERVFELLENPVS
HHHCCHHCCCCCCCCCHHHHHHHHHCCCEEECCCEEEECCCCCCCCCHHHHHHHHHHHHH
SFTKEDGEVIYHGK
HHHCCCCCEEEECC
>Mature Secondary Structure 
TSLIFHNPKCGTSRNTLAIMQASGDNPEVIEYLKTPPSREYLVELLAKMALSPRELLRS
CCCEEECCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHH
KESINDELGLDNPALSDDEIIDAMIDHPILINRPIVVTDKGAALCRPSERVFELLENPVS
HHHCCHHCCCCCCCCCHHHHHHHHHCCCEEECCCEEEECCCCCCCCCHHHHHHHHHHHHH
SFTKEDGEVIYHGK
HHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3021763; 1703401; 1704144 [H]