Click here to switch to the map view.

The map label for this gene is trpD [H]

Identifier: 93006268

GI number: 93006268

Start: 1774334

End: 1775473

Strand: Direct

Name: trpD [H]

Synonym: Pcryo_1442

Alternate gene names: 93006268

Gene position: 1774334-1775473 (Clockwise)

Preceding gene: 93006267

Following gene: 93006269

Centisome position: 57.99

GC content: 46.23

Gene sequence:

>1140_bases
ATGATGACCACTGCTCCTTTGCAGAATGTACTTTCAAACGTAACCCGTACGCCAGAAGATATCCATCAGTTGTCAGATGA
CAGTATCCATGAGCTACTAACCACCGCATTAGGTAGGATTTTTCAACACATTGATCTGACCTTTGATGAGATGTATCAAG
TGATGCTAATCATCATGCAAGGCAGATGTAGTGATGCCATGATGGGTGCTATTTTGACCGGTCTGCGTATGAAAGGCGAA
TCAATCGATGAGATTACTGCCTCAGCAAGTGCTATGCGTGCATTAGCGTCAAATATCGCCCCAAAAGACTGTGACTATAT
GGTCGATATCGTTGGTACAGGTGGTGATGGTGCCAACTTATTTAATGTCTCTACAGCGGCAGCGTTGGTAGCAGCAGCAG
CAGGTGCACAAGTTGCCAAACATGGTAACCGCGGTGTGTCAAGCAAATCTGGTAGCTCGGACTTGCTTGAGCAAGCTGGT
ATCAGTCTATCGCTGACGCCTGAGCAAGCGCAAGCCTGTATCGAAGACCAAGGTATTGGCTTTTTATTTGCGCCAAACCA
CCATAGCGCCATGCGTTATGCCAATCCAGTACGCCGTGAGCTAAAATCTAGAACGATTTTTAATATTTTAGGTCCACTCA
CCAACCCTGCTGGTACGCCCAATTTGGTGATTGGCGTTTTTACCGCGCAATTATGTGAACCTTTAGCAAAGGTCATGAAA
AATCTAGGCGCGCGCCATGTGATGGTCGTCGGTGCAAAAGATGGTTTGGATGAAATAAGTCTCGCAACCTCGACCACGGT
GGCTGAATTAAAAGATGGTGAAATTTCTGTCTATGATATGATGCCAGAGGATGCAGGTATTGATTCACAAACCTTGATTG
GGCTTGATGTTGACTCACCAGCGCAAAGCCTTGAGCTAATACGTGCCGCTTTGTCAGGCACAGAGACACATGAACGATCA
GTGCTTAAAGCGCGCGATATGATTGCGTTAAATGCAGGCGCAGCGATATATACTGCAGGACTTGCAAGCAACTATCCAAA
CGGTGTGAGCCGAGCACAAAAAATTATCCAAAATGGCGAGGCTTTAGTGAAGCTTGAGTCTTTGGCACAATATACGCAGC
AATTGGCAGCCAATGCTTAA

Upstream 100 bases:

>100_bases
ACGAGCGCATCATTTGGCTGTTATAGACACCGATAACTTGCCACAGGTAGGCTAGCCGCTAGAAATTATCTAAAAATTTA
AAATAATAATAAGTGAGAAT

Downstream 100 bases:

>100_bases
CTTATAAGTACATAAACCTAGCCATCATAGACTATTTATCTTTAACCATATTTGGATACCGCCATGACTACTAACAAAAC
AGTTGGCTCACATATTCCTT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MMTTAPLQNVLSNVTRTPEDIHQLSDDSIHELLTTALGRIFQHIDLTFDEMYQVMLIIMQGRCSDAMMGAILTGLRMKGE
SIDEITASASAMRALASNIAPKDCDYMVDIVGTGGDGANLFNVSTAAALVAAAAGAQVAKHGNRGVSSKSGSSDLLEQAG
ISLSLTPEQAQACIEDQGIGFLFAPNHHSAMRYANPVRRELKSRTIFNILGPLTNPAGTPNLVIGVFTAQLCEPLAKVMK
NLGARHVMVVGAKDGLDEISLATSTTVAELKDGEISVYDMMPEDAGIDSQTLIGLDVDSPAQSLELIRAALSGTETHERS
VLKARDMIALNAGAAIYTAGLASNYPNGVSRAQKIIQNGEALVKLESLAQYTQQLAANA

Sequences:

>Translated_379_residues
MMTTAPLQNVLSNVTRTPEDIHQLSDDSIHELLTTALGRIFQHIDLTFDEMYQVMLIIMQGRCSDAMMGAILTGLRMKGE
SIDEITASASAMRALASNIAPKDCDYMVDIVGTGGDGANLFNVSTAAALVAAAAGAQVAKHGNRGVSSKSGSSDLLEQAG
ISLSLTPEQAQACIEDQGIGFLFAPNHHSAMRYANPVRRELKSRTIFNILGPLTNPAGTPNLVIGVFTAQLCEPLAKVMK
NLGARHVMVVGAKDGLDEISLATSTTVAELKDGEISVYDMMPEDAGIDSQTLIGLDVDSPAQSLELIRAALSGTETHERS
VLKARDMIALNAGAAIYTAGLASNYPNGVSRAQKIIQNGEALVKLESLAQYTQQLAANA
>Mature_379_residues
MMTTAPLQNVLSNVTRTPEDIHQLSDDSIHELLTTALGRIFQHIDLTFDEMYQVMLIIMQGRCSDAMMGAILTGLRMKGE
SIDEITASASAMRALASNIAPKDCDYMVDIVGTGGDGANLFNVSTAAALVAAAAGAQVAKHGNRGVSSKSGSSDLLEQAG
ISLSLTPEQAQACIEDQGIGFLFAPNHHSAMRYANPVRRELKSRTIFNILGPLTNPAGTPNLVIGVFTAQLCEPLAKVMK
NLGARHVMVVGAKDGLDEISLATSTTVAELKDGEISVYDMMPEDAGIDSQTLIGLDVDSPAQSLELIRAALSGTETHERS
VLKARDMIALNAGAAIYTAGLASNYPNGVSRAQKIIQNGEALVKLESLAQYTQQLAANA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=283, Percent_Identity=42.4028268551237, Blast_Score=204, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6320561, Length=363, Percent_Identity=27.2727272727273, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 40041; Mature: 40041

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTTAPLQNVLSNVTRTPEDIHQLSDDSIHELLTTALGRIFQHIDLTFDEMYQVMLIIMQ
CCCCHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GRCSDAMMGAILTGLRMKGESIDEITASASAMRALASNIAPKDCDYMVDIVGTGGDGANL
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCE
FNVSTAAALVAAAAGAQVAKHGNRGVSSKSGSSDLLEQAGISLSLTPEQAQACIEDQGIG
EHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCEEEECHHHHHHHHHHCCCE
FLFAPNHHSAMRYANPVRRELKSRTIFNILGPLTNPAGTPNLVIGVFTAQLCEPLAKVMK
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
NLGARHVMVVGAKDGLDEISLATSTTVAELKDGEISVYDMMPEDAGIDSQTLIGLDVDSP
HCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCH
AQSLELIRAALSGTETHERSVLKARDMIALNAGAAIYTAGLASNYPNGVSRAQKIIQNGE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCCHHHHHHHHHHCCH
ALVKLESLAQYTQQLAANA
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMTTAPLQNVLSNVTRTPEDIHQLSDDSIHELLTTALGRIFQHIDLTFDEMYQVMLIIMQ
CCCCHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
GRCSDAMMGAILTGLRMKGESIDEITASASAMRALASNIAPKDCDYMVDIVGTGGDGANL
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCE
FNVSTAAALVAAAAGAQVAKHGNRGVSSKSGSSDLLEQAGISLSLTPEQAQACIEDQGIG
EHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCEEEECHHHHHHHHHHCCCE
FLFAPNHHSAMRYANPVRRELKSRTIFNILGPLTNPAGTPNLVIGVFTAQLCEPLAKVMK
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
NLGARHVMVVGAKDGLDEISLATSTTVAELKDGEISVYDMMPEDAGIDSQTLIGLDVDSP
HCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCH
AQSLELIRAALSGTETHERSVLKARDMIALNAGAAIYTAGLASNYPNGVSRAQKIIQNGE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCCHHHHHHHHHHCCH
ALVKLESLAQYTQQLAANA
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA