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The map label for this gene is serC [H]

Identifier: 93006260

GI number: 93006260

Start: 1763312

End: 1764421

Strand: Reverse

Name: serC [H]

Synonym: Pcryo_1434

Alternate gene names: 93006260

Gene position: 1764421-1763312 (Counterclockwise)

Preceding gene: 93006261

Following gene: 93006259

Centisome position: 57.66

GC content: 45.32

Gene sequence:

>1110_bases
ATGACTACCAAAGCCGCTCCTAACCGTGTACCTAATTTTTCAGCAGGACCTGCTACTATACCGACCGCCGTGTTATCACG
TGCTCAAGAAGAGTTGCTAGACTGGCAAGGACGCGGCGTATCGGTGATGGAAATCAGCCATCGTAGTAAAGAATACATCG
CGATTACTGAAAAAGCTGAAGCCAAACTGCGCTCATTGATGGATATTCCAGACAATTATAAAGTGCTGTTTTTGCAAGGT
GGCGCCAGCTTACAGTTTTCAGCCATTCCATTAAATCTGTTAAATGGTGGACGCGGTGACTACCTCACTACTGGTGCTTG
GTCAGGAAAAGCCATTAAAGAAGCGCAGCGTTATGCTAATTTAGGCCTTGGTGAGGTTAATCTGGTGGCAACAGGCAAAG
ACAGTAACTTTACCGACGTGCCAGACCAAAGTGACTGGAACCTGAGCGAAGATGCGGCGTATTTCCACTACTGTGCCAAT
GAGACCATTCATGGTTTGCAAGTATTTGAGCCACCGAAAGTTGATGCGCCTATTATCGTTGATATGTCATCTTGCATTTT
GTCACAACCGATTGATGTGTCTAAATTTGGGATGATTTATGCTGGTGCGCAAAAGAATATTGGTCCAGCTGGGCTAATTA
TTGTCATCATTCGCGAAGACTTATTAGGGCAGGCAAGTGAGTGGTGCCCGCTACTCATGAACTATGAACACCAAGCCGAA
AAAGAATCTATGTCAAACACGCCAGCGACGTACTCTTGGTACTTGGCAGGTCTGGTCTTTGATTGGTTAGAAGAGCAAGG
CGGCGTTGCTGCTATCGGAAAAATCAATCAACAAAAAGCGGATTTGCTCTATAAAACGATTGATGATAGTCGCTTTTATA
GCAATCCAGTCGACACTAAGTATCGTTCTATCATGAACGTCCCATTTACGTTGGCTGACAGCAGTCTTGATAAAGTATTT
TTAGAAGAGTCAGAAGCAGCAGGTTTACTGCATCTAAAAGGTCACCGCGATGTTGGCGGTATGCGTGCTAGCATCTACAA
TGCGGTGTCGCTAGACTGGGTACAGCAGCTGGTCGACTTTATGATTGCGTTTGAAAAGAAGCACGCCTAA

Upstream 100 bases:

>100_bases
AATAAAAACGTAAGAAGTATTTCAATGGTTAACTTTTAAATCCCATAATTTTTAAAACCCAACTAACAACGATGATTTTA
TCATATTTAGGATAATGATT

Downstream 100 bases:

>100_bases
GTCAGTACAGTTTTTGGAAAAAAGACGCACTTTTATGAGTTGCGTCTTTTTTTATGAGCATTGATGCTTATCATTGGTGA
ATAATGTGTCATAGAGTCAC

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MTTKAAPNRVPNFSAGPATIPTAVLSRAQEELLDWQGRGVSVMEISHRSKEYIAITEKAEAKLRSLMDIPDNYKVLFLQG
GASLQFSAIPLNLLNGGRGDYLTTGAWSGKAIKEAQRYANLGLGEVNLVATGKDSNFTDVPDQSDWNLSEDAAYFHYCAN
ETIHGLQVFEPPKVDAPIIVDMSSCILSQPIDVSKFGMIYAGAQKNIGPAGLIIVIIREDLLGQASEWCPLLMNYEHQAE
KESMSNTPATYSWYLAGLVFDWLEEQGGVAAIGKINQQKADLLYKTIDDSRFYSNPVDTKYRSIMNVPFTLADSSLDKVF
LEESEAAGLLHLKGHRDVGGMRASIYNAVSLDWVQQLVDFMIAFEKKHA

Sequences:

>Translated_369_residues
MTTKAAPNRVPNFSAGPATIPTAVLSRAQEELLDWQGRGVSVMEISHRSKEYIAITEKAEAKLRSLMDIPDNYKVLFLQG
GASLQFSAIPLNLLNGGRGDYLTTGAWSGKAIKEAQRYANLGLGEVNLVATGKDSNFTDVPDQSDWNLSEDAAYFHYCAN
ETIHGLQVFEPPKVDAPIIVDMSSCILSQPIDVSKFGMIYAGAQKNIGPAGLIIVIIREDLLGQASEWCPLLMNYEHQAE
KESMSNTPATYSWYLAGLVFDWLEEQGGVAAIGKINQQKADLLYKTIDDSRFYSNPVDTKYRSIMNVPFTLADSSLDKVF
LEESEAAGLLHLKGHRDVGGMRASIYNAVSLDWVQQLVDFMIAFEKKHA
>Mature_368_residues
TTKAAPNRVPNFSAGPATIPTAVLSRAQEELLDWQGRGVSVMEISHRSKEYIAITEKAEAKLRSLMDIPDNYKVLFLQGG
ASLQFSAIPLNLLNGGRGDYLTTGAWSGKAIKEAQRYANLGLGEVNLVATGKDSNFTDVPDQSDWNLSEDAAYFHYCANE
TIHGLQVFEPPKVDAPIIVDMSSCILSQPIDVSKFGMIYAGAQKNIGPAGLIIVIIREDLLGQASEWCPLLMNYEHQAEK
ESMSNTPATYSWYLAGLVFDWLEEQGGVAAIGKINQQKADLLYKTIDDSRFYSNPVDTKYRSIMNVPFTLADSSLDKVFL
EESEAAGLLHLKGHRDVGGMRASIYNAVSLDWVQQLVDFMIAFEKKHA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=372, Percent_Identity=48.6559139784946, Blast_Score=360, Evalue=1e-99,
Organism=Homo sapiens, GI10863955, Length=367, Percent_Identity=43.5967302452316, Blast_Score=305, Evalue=4e-83,
Organism=Escherichia coli, GI1787136, Length=363, Percent_Identity=55.3719008264463, Blast_Score=408, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17506897, Length=373, Percent_Identity=43.6997319034853, Blast_Score=316, Evalue=1e-86,
Organism=Saccharomyces cerevisiae, GI6324758, Length=390, Percent_Identity=40.7692307692308, Blast_Score=261, Evalue=1e-70,
Organism=Drosophila melanogaster, GI21356589, Length=367, Percent_Identity=48.2288828337875, Blast_Score=352, Evalue=2e-97,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40666; Mature: 40534

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKAAPNRVPNFSAGPATIPTAVLSRAQEELLDWQGRGVSVMEISHRSKEYIAITEKAE
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECHHH
AKLRSLMDIPDNYKVLFLQGGASLQFSAIPLNLLNGGRGDYLTTGAWSGKAIKEAQRYAN
HHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHC
LGLGEVNLVATGKDSNFTDVPDQSDWNLSEDAAYFHYCANETIHGLQVFEPPKVDAPIIV
CCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCEEE
DMSSCILSQPIDVSKFGMIYAGAQKNIGPAGLIIVIIREDLLGQASEWCPLLMNYEHQAE
ECHHHHHCCCCCHHHCCEEEECCCCCCCCCCEEEEEEECHHHCCCHHCCHHHHCCCHHHH
KESMSNTPATYSWYLAGLVFDWLEEQGGVAAIGKINQQKADLLYKTIDDSRFYSNPVDTK
HHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHH
YRSIMNVPFTLADSSLDKVFLEESEAAGLLHLKGHRDVGGMRASIYNAVSLDWVQQLVDF
HHHHHCCCEEECCCCHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
MIAFEKKHA
HHHHHHCCC
>Mature Secondary Structure 
TTKAAPNRVPNFSAGPATIPTAVLSRAQEELLDWQGRGVSVMEISHRSKEYIAITEKAE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECHHH
AKLRSLMDIPDNYKVLFLQGGASLQFSAIPLNLLNGGRGDYLTTGAWSGKAIKEAQRYAN
HHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHC
LGLGEVNLVATGKDSNFTDVPDQSDWNLSEDAAYFHYCANETIHGLQVFEPPKVDAPIIV
CCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCEEE
DMSSCILSQPIDVSKFGMIYAGAQKNIGPAGLIIVIIREDLLGQASEWCPLLMNYEHQAE
ECHHHHHCCCCCHHHCCEEEECCCCCCCCCCEEEEEEECHHHCCCHHCCHHHHCCCHHHH
KESMSNTPATYSWYLAGLVFDWLEEQGGVAAIGKINQQKADLLYKTIDDSRFYSNPVDTK
HHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHH
YRSIMNVPFTLADSSLDKVFLEESEAAGLLHLKGHRDVGGMRASIYNAVSLDWVQQLVDF
HHHHHCCCEEECCCCHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
MIAFEKKHA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA