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The map label for this gene is cysH [H]

Identifier: 93006222

GI number: 93006222

Start: 1706908

End: 1707546

Strand: Direct

Name: cysH [H]

Synonym: Pcryo_1396

Alternate gene names: 93006222

Gene position: 1706908-1707546 (Clockwise)

Preceding gene: 93006221

Following gene: 93006223

Centisome position: 55.78

GC content: 43.66

Gene sequence:

>639_bases
ATGAGCCAATTACACCCAAATCTAGATATCGATCAAGCCAACCAAGACTTGCAAGGTCAAACACCAGAACAAATCGTAGA
ATGGGCATTAAGCCAAGCGAAAAACCCAATCATTACCACTAACTTCCGTCCTTACGAGTCAGCGATTTTGCATTTGGTCG
CATCGCTGCGCCCTAACATCACCGTATTGTGGGTAGATTCTGGCTATAATACTGACGCCACTTACCAGTTTGCCAATAAA
GTCATTCGTGATTTAAATTTAAACGTGATCACCTATATTCCTAAGCAAACTGCTGCCCATCGTGACGTGACGATGGAAGG
CATCCCTGGTATTGATAACCCACTACATGATGAGTTCACCGATCAAGTGAAGCTTGAGCCATTCCGCCGCGCTTTAGATG
AGCTAAAGCCTGATGTTTGGTTCAATGCTATTCGTAAAGATCAAACCGAATTCCGTCAAGGTCTTGATGTCCTGAGCTTG
TCTAAAGACGGCGTGTTAAAAGTCGCACCGTTATTTGATAAGACAGATAGCGATTTGGATGTTTATCTTGAAGAACATAA
CCTACCGAATGAGTTCGATTACTTCGATCCGACTAAAGTAGAAGAGCACCGCGAATGTGGCTTGCATACGCAGTTGTAA

Upstream 100 bases:

>100_bases
ATGTTTGCAGGCACTTAGTTTTAGAATAAATCATAAGCACTTATATTAGTTACTTTTCACTCAAATCATTTTTACATGAA
CTTTCATCAAGGAATCTACC

Downstream 100 bases:

>100_bases
TTGCTAAATACAGAATTGTGATTTAATAAATACAATGCATAAAAATCCCGCTTAACCGGTTTATACCGAGTTAAGCGGGA
TTTTTTTAGTATCATAATTT

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSQLHPNLDIDQANQDLQGQTPEQIVEWALSQAKNPIITTNFRPYESAILHLVASLRPNITVLWVDSGYNTDATYQFANK
VIRDLNLNVITYIPKQTAAHRDVTMEGIPGIDNPLHDEFTDQVKLEPFRRALDELKPDVWFNAIRKDQTEFRQGLDVLSL
SKDGVLKVAPLFDKTDSDLDVYLEEHNLPNEFDYFDPTKVEEHRECGLHTQL

Sequences:

>Translated_212_residues
MSQLHPNLDIDQANQDLQGQTPEQIVEWALSQAKNPIITTNFRPYESAILHLVASLRPNITVLWVDSGYNTDATYQFANK
VIRDLNLNVITYIPKQTAAHRDVTMEGIPGIDNPLHDEFTDQVKLEPFRRALDELKPDVWFNAIRKDQTEFRQGLDVLSL
SKDGVLKVAPLFDKTDSDLDVYLEEHNLPNEFDYFDPTKVEEHRECGLHTQL
>Mature_211_residues
SQLHPNLDIDQANQDLQGQTPEQIVEWALSQAKNPIITTNFRPYESAILHLVASLRPNITVLWVDSGYNTDATYQFANKV
IRDLNLNVITYIPKQTAAHRDVTMEGIPGIDNPLHDEFTDQVKLEPFRRALDELKPDVWFNAIRKDQTEFRQGLDVLSLS
KDGVLKVAPLFDKTDSDLDVYLEEHNLPNEFDYFDPTKVEEHRECGLHTQL

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=230, Percent_Identity=29.5652173913043, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR011800
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 24356; Mature: 24224

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLHPNLDIDQANQDLQGQTPEQIVEWALSQAKNPIITTNFRPYESAILHLVASLRPNI
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCCE
TVLWVDSGYNTDATYQFANKVIRDLNLNVITYIPKQTAAHRDVTMEGIPGIDNPLHDEFT
EEEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEECCCCCCCCCCCHHHH
DQVKLEPFRRALDELKPDVWFNAIRKDQTEFRQGLDVLSLSKDGVLKVAPLFDKTDSDLD
HHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCCCE
VYLEEHNLPNEFDYFDPTKVEEHRECGLHTQL
EEEECCCCCCCCCCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
SQLHPNLDIDQANQDLQGQTPEQIVEWALSQAKNPIITTNFRPYESAILHLVASLRPNI
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCCE
TVLWVDSGYNTDATYQFANKVIRDLNLNVITYIPKQTAAHRDVTMEGIPGIDNPLHDEFT
EEEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEECCCCCCCCCCCHHHH
DQVKLEPFRRALDELKPDVWFNAIRKDQTEFRQGLDVLSLSKDGVLKVAPLFDKTDSDLD
HHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCCCE
VYLEEHNLPNEFDYFDPTKVEEHRECGLHTQL
EEEECCCCCCCCCCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA