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The map label for this gene is sir1 [H]

Identifier: 93006220

GI number: 93006220

Start: 1704551

End: 1706236

Strand: Direct

Name: sir1 [H]

Synonym: Pcryo_1394

Alternate gene names: 93006220

Gene position: 1704551-1706236 (Clockwise)

Preceding gene: 93006218

Following gene: 93006221

Centisome position: 55.71

GC content: 45.67

Gene sequence:

>1686_bases
ATGTATCAATATAACTACGCTGACCAAACCTTGGTAGAAGAACGAGTCGCCCAGTTTCGCGACCAAACCGAACGGTTTTT
GGCGGGTGAGCTGCCAGAAGAACAGTTTTTGCCACTGCGTTTGCAGAATGGTCTTTATATTCAGCGTTATGCGCCGATGT
TACGTATTGCTATTCCTTACGGCCTACTAGCCAGCTATCAACTGCGTAAACTGGCGGAGATTACCCGTAAGTACGATAAA
GGTTACGGACACTTCACGACCCGTACCAATATCCAGCTAAACTGGCCAAAGCTAGAAGAAGTGCCAGATATTTTGGCGGA
GCTAGCATCGGTACAGATGCATGCCATTCAAACCTCAGGCAACTGTATTCGTAACACGACTACCGATCCTTATGCCGGTA
TTCATCAAGAAGAGATTGCGGATCCACGCCCTTATTGCGAAATTATCCGTCAGTGGTCTACCTTTCATCCTGAATTTGCT
TTTTTACCGCGTAAATTTAAGATTGCTGTCGTTGGTACTGCCAATGATCGCGCGGCGACGCAAGTACATGATGTTGGATT
ACATGTAAAAACCAATGACACAGGCGAGATTGGTTTTGAAGTATTGGTAGGTGGCGGTCTTGGCCGTACACCAGTGATTG
GTAAAGTAATTAACGAATTCTTGCCACGTCAGCATCTGCTTAGCTATCTAGACGCTATTTTGCGCGTTTATAACCTGCAT
GGTCGCCGCGATAATAAATACAAAGCGCGTATCAAAATATTGGTCGAGAGCATGGGCGGTCCTGCCTTTGCGAAATTGGT
CGATGCTGAGTGGGAAGCCCATACCAAAGACGGTCCACTGACTTTGACCGATGCCAATTTTGACACTGCTATTGGCTTCT
TTAGTGAGCCTGATTATGTTGGCTTTGATGCCTTACAAGTACAGTCTGACTTGCAACAGCAACTCAATGCGAATAAAGAT
TTTGCCGATTGGTATAACCAAAATACAGTCGCGCATAAAATAGCAGGCTATCGCGCCGTCGTAATTTCTCTAAAAGCAGG
CTTGGTCGATGGAACCTACGTACCATCTGGTGATGTCAGCGAATCACAAATGGATGCTCTCGCGGATCTGTCAGACAAAT
ATAGCTTTGGTGAATTGCGCGGTACTTATCAGCAAAATCTCGTATTCTCTGATGTGCAAACCAATCAGCTATATGAGCTA
TGGCAACAGCTGTCTGAACTGCATTTAGCGCGTGCCAACATAAACACACTAACCGATATGATTGTTTGCCCAGGTTGGGA
CTATTGCTCACTCGCCAATGCTACGACTCACAACATCGCTGAGCAAATCGAGAAGCAATTTGATGATCTCGATTACCTTT
ATGACTTGGGTGAAATTCGCCTAAATATGTCTGGCTGCATGAATGCCTGTGCGCATCACCATACAGGTGATATCGGTATA
TTGGGTGTTGATAAAAAGGGTGAGCATTGGTATCAAATCAGCCTTGGCGGCAACTCTAGCAACGATGCCAAGGTCGGTAA
AATATTGGGTAAAGCAGTACCAGCCGAAGATGTGGCGATTACCCTACAAAAAATACTGGACGTCTATTTAGAGCAGCGCG
TGAGCAATGAGAACGACGTAGAAGCTTTTAGTGACTTGGTCAATCGCGTTGGCGTGGCACCTTTTAAGGAGAAGGTCTAT
GGGTAA

Upstream 100 bases:

>100_bases
AGCTGAACGGTACACATTACGATCGACAACAAAATATATTACACACGCAAATCATTTTCGTCGCTGCTTTTAAGACTAAA
AACAAAATTGAGATTACGTC

Downstream 100 bases:

>100_bases
TCATCATGTGTTAAACAGCAAAGGTATTGATATCGGTCAAAGTGATACGTGGTTGGCGCTTAATACCGATGAGCTACCAG
ATGGCATTGCTCTTAGCCAT

Product: nitrite and sulfite reductase 4Fe-4S region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MYQYNYADQTLVEERVAQFRDQTERFLAGELPEEQFLPLRLQNGLYIQRYAPMLRIAIPYGLLASYQLRKLAEITRKYDK
GYGHFTTRTNIQLNWPKLEEVPDILAELASVQMHAIQTSGNCIRNTTTDPYAGIHQEEIADPRPYCEIIRQWSTFHPEFA
FLPRKFKIAVVGTANDRAATQVHDVGLHVKTNDTGEIGFEVLVGGGLGRTPVIGKVINEFLPRQHLLSYLDAILRVYNLH
GRRDNKYKARIKILVESMGGPAFAKLVDAEWEAHTKDGPLTLTDANFDTAIGFFSEPDYVGFDALQVQSDLQQQLNANKD
FADWYNQNTVAHKIAGYRAVVISLKAGLVDGTYVPSGDVSESQMDALADLSDKYSFGELRGTYQQNLVFSDVQTNQLYEL
WQQLSELHLARANINTLTDMIVCPGWDYCSLANATTHNIAEQIEKQFDDLDYLYDLGEIRLNMSGCMNACAHHHTGDIGI
LGVDKKGEHWYQISLGGNSSNDAKVGKILGKAVPAEDVAITLQKILDVYLEQRVSNENDVEAFSDLVNRVGVAPFKEKVY
G

Sequences:

>Translated_561_residues
MYQYNYADQTLVEERVAQFRDQTERFLAGELPEEQFLPLRLQNGLYIQRYAPMLRIAIPYGLLASYQLRKLAEITRKYDK
GYGHFTTRTNIQLNWPKLEEVPDILAELASVQMHAIQTSGNCIRNTTTDPYAGIHQEEIADPRPYCEIIRQWSTFHPEFA
FLPRKFKIAVVGTANDRAATQVHDVGLHVKTNDTGEIGFEVLVGGGLGRTPVIGKVINEFLPRQHLLSYLDAILRVYNLH
GRRDNKYKARIKILVESMGGPAFAKLVDAEWEAHTKDGPLTLTDANFDTAIGFFSEPDYVGFDALQVQSDLQQQLNANKD
FADWYNQNTVAHKIAGYRAVVISLKAGLVDGTYVPSGDVSESQMDALADLSDKYSFGELRGTYQQNLVFSDVQTNQLYEL
WQQLSELHLARANINTLTDMIVCPGWDYCSLANATTHNIAEQIEKQFDDLDYLYDLGEIRLNMSGCMNACAHHHTGDIGI
LGVDKKGEHWYQISLGGNSSNDAKVGKILGKAVPAEDVAITLQKILDVYLEQRVSNENDVEAFSDLVNRVGVAPFKEKVY
G
>Mature_561_residues
MYQYNYADQTLVEERVAQFRDQTERFLAGELPEEQFLPLRLQNGLYIQRYAPMLRIAIPYGLLASYQLRKLAEITRKYDK
GYGHFTTRTNIQLNWPKLEEVPDILAELASVQMHAIQTSGNCIRNTTTDPYAGIHQEEIADPRPYCEIIRQWSTFHPEFA
FLPRKFKIAVVGTANDRAATQVHDVGLHVKTNDTGEIGFEVLVGGGLGRTPVIGKVINEFLPRQHLLSYLDAILRVYNLH
GRRDNKYKARIKILVESMGGPAFAKLVDAEWEAHTKDGPLTLTDANFDTAIGFFSEPDYVGFDALQVQSDLQQQLNANKD
FADWYNQNTVAHKIAGYRAVVISLKAGLVDGTYVPSGDVSESQMDALADLSDKYSFGELRGTYQQNLVFSDVQTNQLYEL
WQQLSELHLARANINTLTDMIVCPGWDYCSLANATTHNIAEQIEKQFDDLDYLYDLGEIRLNMSGCMNACAHHHTGDIGI
LGVDKKGEHWYQISLGGNSSNDAKVGKILGKAVPAEDVAITLQKILDVYLEQRVSNENDVEAFSDLVNRVGVAPFKEKVY
G

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

None

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 63100; Mature: 63100

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00365 NIR_SIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQYNYADQTLVEERVAQFRDQTERFLAGELPEEQFLPLRLQNGLYIQRYAPMLRIAIPY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCEEECCCEEEEHHCCHHHHHHHH
GLLASYQLRKLAEITRKYDKGYGHFTTRTNIQLNWPKLEEVPDILAELASVQMHAIQTSG
HHHHHHHHHHHHHHHHHHHCCCCCEEEECEEEECCCCHHHHHHHHHHHHHHHHHEEECCC
NCIRNTTTDPYAGIHQEEIADPRPYCEIIRQWSTFHPEFAFLPRKFKIAVVGTANDRAAT
CEEECCCCCCCCCCCHHHCCCCCHHHHHHHHHHCCCCCHHCCCCEEEEEEEECCCCCHHH
QVHDVGLHVKTNDTGEIGFEVLVGGGLGRTPVIGKVINEFLPRQHLLSYLDAILRVYNLH
HHHHCEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
GRRDNKYKARIKILVESMGGPAFAKLVDAEWEAHTKDGPLTLTDANFDTAIGFFSEPDYV
CCCCCCHHHHHEEEEHHCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCEECCCCCCCCC
GFDALQVQSDLQQQLNANKDFADWYNQNTVAHKIAGYRAVVISLKAGLVDGTYVPSGDVS
CCHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCC
ESQMDALADLSDKYSFGELRGTYQQNLVFSDVQTNQLYELWQQLSELHLARANINTLTDM
HHHHHHHHHHHCCCCHHHHCCHHHHCEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
IVCPGWDYCSLANATTHNIAEQIEKQFDDLDYLYDLGEIRLNMSGCMNACAHHHTGDIGI
HCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHCCCCCEEE
LGVDKKGEHWYQISLGGNSSNDAKVGKILGKAVPAEDVAITLQKILDVYLEQRVSNENDV
EEECCCCCEEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
EAFSDLVNRVGVAPFKEKVYG
HHHHHHHHHCCCCCHHHHCCC
>Mature Secondary Structure
MYQYNYADQTLVEERVAQFRDQTERFLAGELPEEQFLPLRLQNGLYIQRYAPMLRIAIPY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCEEECCCEEEEHHCCHHHHHHHH
GLLASYQLRKLAEITRKYDKGYGHFTTRTNIQLNWPKLEEVPDILAELASVQMHAIQTSG
HHHHHHHHHHHHHHHHHHHCCCCCEEEECEEEECCCCHHHHHHHHHHHHHHHHHEEECCC
NCIRNTTTDPYAGIHQEEIADPRPYCEIIRQWSTFHPEFAFLPRKFKIAVVGTANDRAAT
CEEECCCCCCCCCCCHHHCCCCCHHHHHHHHHHCCCCCHHCCCCEEEEEEEECCCCCHHH
QVHDVGLHVKTNDTGEIGFEVLVGGGLGRTPVIGKVINEFLPRQHLLSYLDAILRVYNLH
HHHHCEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
GRRDNKYKARIKILVESMGGPAFAKLVDAEWEAHTKDGPLTLTDANFDTAIGFFSEPDYV
CCCCCCHHHHHEEEEHHCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCEECCCCCCCCC
GFDALQVQSDLQQQLNANKDFADWYNQNTVAHKIAGYRAVVISLKAGLVDGTYVPSGDVS
CCHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCC
ESQMDALADLSDKYSFGELRGTYQQNLVFSDVQTNQLYELWQQLSELHLARANINTLTDM
HHHHHHHHHHHCCCCHHHHCCHHHHCEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHH
IVCPGWDYCSLANATTHNIAEQIEKQFDDLDYLYDLGEIRLNMSGCMNACAHHHTGDIGI
HCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHCCCCCEEE
LGVDKKGEHWYQISLGGNSSNDAKVGKILGKAVPAEDVAITLQKILDVYLEQRVSNENDV
EEECCCCCEEEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHH
EAFSDLVNRVGVAPFKEKVYG
HHHHHHHHHCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA