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The map label for this gene is cat1 [H]

Identifier: 93006055

GI number: 93006055

Start: 1493563

End: 1495113

Strand: Direct

Name: cat1 [H]

Synonym: Pcryo_1227

Alternate gene names: 93006055

Gene position: 1493563-1495113 (Clockwise)

Preceding gene: 93006053

Following gene: 93006057

Centisome position: 48.81

GC content: 46.1

Gene sequence:

>1551_bases
ATGACATCATTAAATCATGAAGGTCGCGTGCTTCACGACGGTCTAAGCAAAAAAATTATGTCTGCTGATCAAGCAGCAGC
GTTCATCAAAAACGACATGAATGTCGGTATGAGTGGCTTTACCGGTGCCGGTTACCCAAAAGCGATACCCGCTGCGCTTG
CCAAACATATGGAAGCGGCTCATGCTCGCGGTGAAGACTTTCAAATTGGTTTATTGACAGGTGCCTCTACCGCAACCGAA
TGTGATGGCGTATTGGCAGAAGCGAACGGCATCAAGTGGCGCACGCCATATCAATCAGAGCCTGCTTTACGTAAACAAAT
CAACGCAGGTGAAGCGCATTATTTCGATATGCATTTATCGCATGTAGCGCAGCAGAGCACCATCGGTTTCTATGGCAAGA
TGCATATAGCGGTCGTTGAAGTGTCGGGTATTTTGCCAGATGGTCGTTTGATTCCATCGACTTCTATCGGTAACAATAAT
GCCTGGTTAGAAAATGCAGACAAAATCATCTTAGAAGTGAACGCGCAGCAAAGCTTGATGTTAGAAGGTATGCACGATGT
CTATAATGATATCGGTATGCCGCCAAACCGCAAGCCGATTCCACTTGTGACCCCAGGCGGACGCATTGGTGTGCCGTATC
TACATTGTGACTTGGATAAAGTGGTTGGCGTTGTCCTAACGAACTCGCCTGATCGCAACAGCAAGTTTGCTGATCCTGAT
GAGTGTTCAAACAAAATAGCCAGTCATATCATTGATTTCTTCCATGATGAAGTCAAAAAAGGTCGCATGCCAGAAAATTT
ATTACCGATCCAGTCTGGTGTAGGTAACGTAGCCAATGCCGTATTGGCAGGACTACAAAACAGCCCGTTTGAGAATTTGA
CCGGCTACACAGAAGTATTGCAAGATGGTATGTTAGACCTAATTATGTCTGGCAAAATGACCATGGCATCTGCCACTGCA
CTGTCATTAAGCCCAGATGCGCTAGAGCGTTTTAATGCCAATATCGAAGAGCTGCGTGCGCGTATTGTATTGCGTCCACA
AGAAATCACCAACCATCCTGAAGTCGCGCGTCGCTTAGGTGTATTGGCCATTAATGCCATGATTGAATGCGACCTTTATG
GTAACGTCAACTCAACCCACGTCATGGGAACTAACATGATGAATGGCTTGGGCGGTTCAGGTGATTTCGCCCGTAACGCT
TATACGTCATTCTTTGTATCGCCATCAGTGGCAAAAGATGGCGCCATCTCTTGTATTACGCCGATGGTCTCGCATCACGA
CCATACTGAGCATGATGTGATGGTCATTGTCACCGAACAAGGATTGGCAGATTTGCGTGGTTTATCGCCGCGTCAACGTG
CAAAATCAATTATCGATAACTGTGCCCATCCTGACTATCGCCCAATGCTACAAGATTATTTTGATCGTGCTTCAGATACG
GCCGGTATGCAAACGCCGCATATCTTGGACGAAGCTTTATCATGGCATCAGCGTTATGTTGAAACGGGTGATATGCGTAT
CAAAAAATCAGCTTACAAAATTGCCGTTTAA

Upstream 100 bases:

>100_bases
GTTGCTAATATGCAGCAATGCATTTTATTGTTGGTTTCGTATCAAACGCTTCATCGCGAAGTGGTTTGATTTTAATATGG
AAGTTACTAGGAAAAAAGGT

Downstream 100 bases:

>100_bases
TATAATAGATATTATAACAGCATAAATAAATTTCAAAAAAACGCCCCTTATTTAATTTAAGGGGCGTTTTTTTGTGCAAC
GTTAAGTGATTTATTGACGA

Product: Acetyl-CoA hydrolase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MTSLNHEGRVLHDGLSKKIMSADQAAAFIKNDMNVGMSGFTGAGYPKAIPAALAKHMEAAHARGEDFQIGLLTGASTATE
CDGVLAEANGIKWRTPYQSEPALRKQINAGEAHYFDMHLSHVAQQSTIGFYGKMHIAVVEVSGILPDGRLIPSTSIGNNN
AWLENADKIILEVNAQQSLMLEGMHDVYNDIGMPPNRKPIPLVTPGGRIGVPYLHCDLDKVVGVVLTNSPDRNSKFADPD
ECSNKIASHIIDFFHDEVKKGRMPENLLPIQSGVGNVANAVLAGLQNSPFENLTGYTEVLQDGMLDLIMSGKMTMASATA
LSLSPDALERFNANIEELRARIVLRPQEITNHPEVARRLGVLAINAMIECDLYGNVNSTHVMGTNMMNGLGGSGDFARNA
YTSFFVSPSVAKDGAISCITPMVSHHDHTEHDVMVIVTEQGLADLRGLSPRQRAKSIIDNCAHPDYRPMLQDYFDRASDT
AGMQTPHILDEALSWHQRYVETGDMRIKKSAYKIAV

Sequences:

>Translated_516_residues
MTSLNHEGRVLHDGLSKKIMSADQAAAFIKNDMNVGMSGFTGAGYPKAIPAALAKHMEAAHARGEDFQIGLLTGASTATE
CDGVLAEANGIKWRTPYQSEPALRKQINAGEAHYFDMHLSHVAQQSTIGFYGKMHIAVVEVSGILPDGRLIPSTSIGNNN
AWLENADKIILEVNAQQSLMLEGMHDVYNDIGMPPNRKPIPLVTPGGRIGVPYLHCDLDKVVGVVLTNSPDRNSKFADPD
ECSNKIASHIIDFFHDEVKKGRMPENLLPIQSGVGNVANAVLAGLQNSPFENLTGYTEVLQDGMLDLIMSGKMTMASATA
LSLSPDALERFNANIEELRARIVLRPQEITNHPEVARRLGVLAINAMIECDLYGNVNSTHVMGTNMMNGLGGSGDFARNA
YTSFFVSPSVAKDGAISCITPMVSHHDHTEHDVMVIVTEQGLADLRGLSPRQRAKSIIDNCAHPDYRPMLQDYFDRASDT
AGMQTPHILDEALSWHQRYVETGDMRIKKSAYKIAV
>Mature_515_residues
TSLNHEGRVLHDGLSKKIMSADQAAAFIKNDMNVGMSGFTGAGYPKAIPAALAKHMEAAHARGEDFQIGLLTGASTATEC
DGVLAEANGIKWRTPYQSEPALRKQINAGEAHYFDMHLSHVAQQSTIGFYGKMHIAVVEVSGILPDGRLIPSTSIGNNNA
WLENADKIILEVNAQQSLMLEGMHDVYNDIGMPPNRKPIPLVTPGGRIGVPYLHCDLDKVVGVVLTNSPDRNSKFADPDE
CSNKIASHIIDFFHDEVKKGRMPENLLPIQSGVGNVANAVLAGLQNSPFENLTGYTEVLQDGMLDLIMSGKMTMASATAL
SLSPDALERFNANIEELRARIVLRPQEITNHPEVARRLGVLAINAMIECDLYGNVNSTHVMGTNMMNGLGGSGDFARNAY
TSFFVSPSVAKDGAISCITPMVSHHDHTEHDVMVIVTEQGLADLRGLSPRQRAKSIIDNCAHPDYRPMLQDYFDRASDTA
GMQTPHILDEALSWHQRYVETGDMRIKKSAYKIAV

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=487, Percent_Identity=45.3798767967146, Blast_Score=444, Evalue=1e-126,
Organism=Caenorhabditis elegans, GI17538151, Length=490, Percent_Identity=26.3265306122449, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32563853, Length=247, Percent_Identity=31.9838056680162, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319456, Length=514, Percent_Identity=42.0233463035019, Blast_Score=403, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 56181; Mature: 56049

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLNHEGRVLHDGLSKKIMSADQAAAFIKNDMNVGMSGFTGAGYPKAIPAALAKHMEAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
HARGEDFQIGLLTGASTATECDGVLAEANGIKWRTPYQSEPALRKQINAGEAHYFDMHLS
HCCCCCEEEEEEECCCCCHHHCCEEECCCCCEECCCCCCCCHHHHHCCCCCCEEHHHHHH
HVAQQSTIGFYGKMHIAVVEVSGILPDGRLIPSTSIGNNNAWLENADKIILEVNAQQSLM
HHHHHHCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHH
LEGMHDVYNDIGMPPNRKPIPLVTPGGRIGVPYLHCDLDKVVGVVLTNSPDRNSKFADPD
HHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCEEEECHHHHEEEEEECCCCCCCCCCCHH
ECSNKIASHIIDFFHDEVKKGRMPENLLPIQSGVGNVANAVLAGLQNSPFENLTGYTEVL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHH
QDGMLDLIMSGKMTMASATALSLSPDALERFNANIEELRARIVLRPQEITNHPEVARRLG
HHHHHHHHHCCCCHHHHCEEECCCHHHHHHHCCCHHHHHHHHEECCHHHCCCHHHHHHHH
VLAINAMIECDLYGNVNSTHVMGTNMMNGLGGSGDFARNAYTSFFVSPSVAKDGAISCIT
HHEEEEEEEEEECCCCCCCEEECCHHHHCCCCCCCHHHHHHHHEEECCCCCCCCCHHHHH
PMVSHHDHTEHDVMVIVTEQGLADLRGLSPRQRAKSIIDNCAHPDYRPMLQDYFDRASDT
HHHHCCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
AGMQTPHILDEALSWHQRYVETGDMRIKKSAYKIAV
CCCCCHHHHHHHHHHHHHHHHCCCEEEECCCEEECC
>Mature Secondary Structure 
TSLNHEGRVLHDGLSKKIMSADQAAAFIKNDMNVGMSGFTGAGYPKAIPAALAKHMEAA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
HARGEDFQIGLLTGASTATECDGVLAEANGIKWRTPYQSEPALRKQINAGEAHYFDMHLS
HCCCCCEEEEEEECCCCCHHHCCEEECCCCCEECCCCCCCCHHHHHCCCCCCEEHHHHHH
HVAQQSTIGFYGKMHIAVVEVSGILPDGRLIPSTSIGNNNAWLENADKIILEVNAQQSLM
HHHHHHCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHH
LEGMHDVYNDIGMPPNRKPIPLVTPGGRIGVPYLHCDLDKVVGVVLTNSPDRNSKFADPD
HHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCEEEECHHHHEEEEEECCCCCCCCCCCHH
ECSNKIASHIIDFFHDEVKKGRMPENLLPIQSGVGNVANAVLAGLQNSPFENLTGYTEVL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHH
QDGMLDLIMSGKMTMASATALSLSPDALERFNANIEELRARIVLRPQEITNHPEVARRLG
HHHHHHHHHCCCCHHHHCEEECCCHHHHHHHCCCHHHHHHHHEECCHHHCCCHHHHHHHH
VLAINAMIECDLYGNVNSTHVMGTNMMNGLGGSGDFARNAYTSFFVSPSVAKDGAISCIT
HHEEEEEEEEEECCCCCCCEEECCHHHHCCCCCCCHHHHHHHHEEECCCCCCCCCHHHHH
PMVSHHDHTEHDVMVIVTEQGLADLRGLSPRQRAKSIIDNCAHPDYRPMLQDYFDRASDT
HHHHCCCCCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
AGMQTPHILDEALSWHQRYVETGDMRIKKSAYKIAV
CCCCCHHHHHHHHHHHHHHHHCCCEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]