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The map label for this gene is rutG [H]

Identifier: 93006024

GI number: 93006024

Start: 1449605

End: 1451038

Strand: Direct

Name: rutG [H]

Synonym: Pcryo_1196

Alternate gene names: 93006024

Gene position: 1449605-1451038 (Clockwise)

Preceding gene: 93006022

Following gene: 93006026

Centisome position: 47.37

GC content: 45.47

Gene sequence:

>1434_bases
ATGATAACCCCTCCAAAAAACTCGTCTCAATCGACGCCGCATAGTCAGAAAGAACCATCAACGCCAAATGCATTAGAAGC
AGCAGGTATTGATGTTGCAACTGGCTCGGCGACAATGAACTTACCGCACAACCCAGACTTTGATAATGGTCGCTGGTTTC
CAACATGGCGTCCATATGGCGGTGATTTGGATCGGGATCCGGTTGGCATTAATGAGTATTTACCGCCCTCAAAAAGCATG
CTACTGGGTATACAGCATACCTTTGCGATGTTTGGGGCGACAGTGCTTGCGCCATTATTAATGGGCTTTGATCCAAACTT
AGCGATTTTGATGTCTGGTATTTGTACGGTGATGTTTTTTGTGATTACCGGTGGACGTATGCCAAGTTATTTGGGTTCGA
GTTTTGCTTTTATTGGTCCCGTGATTGCCGTGACGGCATATGCTGGCGTAGGGTTTAATTCCAATCTGAATGTTGCATTG
GGCGGCATTATGGCCTGCGGTATTATTTATGCATTGATAGGTCTGCTGGTCATGAAGACGGGTACAGGCTGGATTGAGCG
CTTAATGCCACCGATTGTTACCGGTGCGATTGTAATGATTATTGGTCTTAATTTAGCGCCTGTGACCATTCAAGGGGTGT
CTGTCAACCAATTTGATGCATGGATGGCGACGTTAACGGTATTGCTTATCAGTGGGGTAGCGGTATTTACCCGCGGCATG
CTACGTCGTTTGCTGTTATTAGTTGGCTTAATATTGTCTTATATTGCTTATTTTGTGATGACCAATGTATTGGGCTATGG
CGTGCCGATTGATTTTAGTAGTGTGTCGACGGCTTCATGGTTTGGTCTGCCAAGTATTCATGCGCCGCGTTTTGAGATGA
GCGCCATTATATTAATTGCCCCTGTCGCCTTTATTTTAGTTGCTGAAAATTTGGGACATTTTAAAGCGGTAGAAGGCATG
ACTAAAGCGCGAGTAACGCCTTATATGGGGCGCGCCTTCTTTGCTGATGGCTTAGCGACGACTTTTTCGGCAGGTTTTGG
TGGTACGGGTGTGACGACTTATGCAGAAAATATCGGCGTGATGGCGGTCACCAAAGTATATAGTACGACTATTTTTGTCG
TAGCAGGTTTGGTTGCTATCATGCTGGGCTTGTCACCGAAATTTGGTGCGATTATTCAAACCATTCCGCCCGCATTATTG
GGCGGTGCTTCTATCGTAGTTTTTGGTTTGATTGCCATCGCTGGTGCGAAAATTTGGATAGACAACCATATCGACTTTAG
TAAAAACAGCAATCTTATCATCGCAGCAGTCACTGTGATCATGGGAACCGGTAACTTTAGCTTGCATCTAGGCGGCTTTG
ATTTGGGTGGCATCGGTACGGCTACCTTAACAGCAATTGTGCTTAACGCTCTATTTAATCGCCAAAAAGACTAA

Upstream 100 bases:

>100_bases
TTTGTTATCTCGTTATTTATTCGAGCTATTATTAGCCTGTATCGTTAATGAGTCATTACCAGTCTGTTATTATTAGCTTA
AGCCTATAGGACAATCGCGC

Downstream 100 bases:

>100_bases
CTTTTTTACTATCTTAAGCTTCAAATAACTCACTATATTGATAAGCAAAAGCCACAATAATCATTGTGGCTTTTATCTAT
TAAGGCGCTTGTTTATGATC

Product: uracil-xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MITPPKNSSQSTPHSQKEPSTPNALEAAGIDVATGSATMNLPHNPDFDNGRWFPTWRPYGGDLDRDPVGINEYLPPSKSM
LLGIQHTFAMFGATVLAPLLMGFDPNLAILMSGICTVMFFVITGGRMPSYLGSSFAFIGPVIAVTAYAGVGFNSNLNVAL
GGIMACGIIYALIGLLVMKTGTGWIERLMPPIVTGAIVMIIGLNLAPVTIQGVSVNQFDAWMATLTVLLISGVAVFTRGM
LRRLLLLVGLILSYIAYFVMTNVLGYGVPIDFSSVSTASWFGLPSIHAPRFEMSAIILIAPVAFILVAENLGHFKAVEGM
TKARVTPYMGRAFFADGLATTFSAGFGGTGVTTYAENIGVMAVTKVYSTTIFVVAGLVAIMLGLSPKFGAIIQTIPPALL
GGASIVVFGLIAIAGAKIWIDNHIDFSKNSNLIIAAVTVIMGTGNFSLHLGGFDLGGIGTATLTAIVLNALFNRQKD

Sequences:

>Translated_477_residues
MITPPKNSSQSTPHSQKEPSTPNALEAAGIDVATGSATMNLPHNPDFDNGRWFPTWRPYGGDLDRDPVGINEYLPPSKSM
LLGIQHTFAMFGATVLAPLLMGFDPNLAILMSGICTVMFFVITGGRMPSYLGSSFAFIGPVIAVTAYAGVGFNSNLNVAL
GGIMACGIIYALIGLLVMKTGTGWIERLMPPIVTGAIVMIIGLNLAPVTIQGVSVNQFDAWMATLTVLLISGVAVFTRGM
LRRLLLLVGLILSYIAYFVMTNVLGYGVPIDFSSVSTASWFGLPSIHAPRFEMSAIILIAPVAFILVAENLGHFKAVEGM
TKARVTPYMGRAFFADGLATTFSAGFGGTGVTTYAENIGVMAVTKVYSTTIFVVAGLVAIMLGLSPKFGAIIQTIPPALL
GGASIVVFGLIAIAGAKIWIDNHIDFSKNSNLIIAAVTVIMGTGNFSLHLGGFDLGGIGTATLTAIVLNALFNRQKD
>Mature_477_residues
MITPPKNSSQSTPHSQKEPSTPNALEAAGIDVATGSATMNLPHNPDFDNGRWFPTWRPYGGDLDRDPVGINEYLPPSKSM
LLGIQHTFAMFGATVLAPLLMGFDPNLAILMSGICTVMFFVITGGRMPSYLGSSFAFIGPVIAVTAYAGVGFNSNLNVAL
GGIMACGIIYALIGLLVMKTGTGWIERLMPPIVTGAIVMIIGLNLAPVTIQGVSVNQFDAWMATLTVLLISGVAVFTRGM
LRRLLLLVGLILSYIAYFVMTNVLGYGVPIDFSSVSTASWFGLPSIHAPRFEMSAIILIAPVAFILVAENLGHFKAVEGM
TKARVTPYMGRAFFADGLATTFSAGFGGTGVTTYAENIGVMAVTKVYSTTIFVVAGLVAIMLGLSPKFGAIIQTIPPALL
GGASIVVFGLIAIAGAKIWIDNHIDFSKNSNLIIAAVTVIMGTGNFSLHLGGFDLGGIGTATLTAIVLNALFNRQKD

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=454, Percent_Identity=22.0264317180617, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI40316845, Length=454, Percent_Identity=22.0264317180617, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87081818, Length=423, Percent_Identity=63.3569739952719, Blast_Score=535, Evalue=1e-153,
Organism=Escherichia coli, GI1788843, Length=423, Percent_Identity=37.3522458628842, Blast_Score=264, Evalue=9e-72,
Organism=Escherichia coli, GI87082181, Length=458, Percent_Identity=26.4192139737991, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1790087, Length=455, Percent_Identity=25.9340659340659, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87082178, Length=411, Percent_Identity=26.5206812652068, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17542262, Length=422, Percent_Identity=25.1184834123223, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71993493, Length=168, Percent_Identity=33.9285714285714, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17542260, Length=168, Percent_Identity=33.9285714285714, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17541904, Length=219, Percent_Identity=27.3972602739726, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17558856, Length=443, Percent_Identity=22.7990970654628, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356175, Length=430, Percent_Identity=23.7209302325581, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 50196; Mature: 50196

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITPPKNSSQSTPHSQKEPSTPNALEAAGIDVATGSATMNLPHNPDFDNGRWFPTWRPYG
CCCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEECCCEEEECCCCCCCCCCEECCCCCCCC
GDLDRDPVGINEYLPPSKSMLLGIQHTFAMFGATVLAPLLMGFDPNLAILMSGICTVMFF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VITGGRMPSYLGSSFAFIGPVIAVTAYAGVGFNSNLNVALGGIMACGIIYALIGLLVMKT
HHCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GTGWIERLMPPIVTGAIVMIIGLNLAPVTIQGVSVNQFDAWMATLTVLLISGVAVFTRGM
CCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LRRLLLLVGLILSYIAYFVMTNVLGYGVPIDFSSVSTASWFGLPSIHAPRFEMSAIILIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHH
PVAFILVAENLGHFKAVEGMTKARVTPYMGRAFFADGLATTFSAGFGGTGVTTYAENIGV
HHHHHHHHHCCCCHHHHCCHHHHCCCHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHCCCH
MAVTKVYSTTIFVVAGLVAIMLGLSPKFGAIIQTIPPALLGGASIVVFGLIAIAGAKIWI
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHCCHHHHHHHHHHHHCCEEEE
DNHIDFSKNSNLIIAAVTVIMGTGNFSLHLGGFDLGGIGTATLTAIVLNALFNRQKD
ECCCCCCCCCCEEEEEEEHHEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MITPPKNSSQSTPHSQKEPSTPNALEAAGIDVATGSATMNLPHNPDFDNGRWFPTWRPYG
CCCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEECCCEEEECCCCCCCCCCEECCCCCCCC
GDLDRDPVGINEYLPPSKSMLLGIQHTFAMFGATVLAPLLMGFDPNLAILMSGICTVMFF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
VITGGRMPSYLGSSFAFIGPVIAVTAYAGVGFNSNLNVALGGIMACGIIYALIGLLVMKT
HHCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GTGWIERLMPPIVTGAIVMIIGLNLAPVTIQGVSVNQFDAWMATLTVLLISGVAVFTRGM
CCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LRRLLLLVGLILSYIAYFVMTNVLGYGVPIDFSSVSTASWFGLPSIHAPRFEMSAIILIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHH
PVAFILVAENLGHFKAVEGMTKARVTPYMGRAFFADGLATTFSAGFGGTGVTTYAENIGV
HHHHHHHHHCCCCHHHHCCHHHHCCCHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHCCCH
MAVTKVYSTTIFVVAGLVAIMLGLSPKFGAIIQTIPPALLGGASIVVFGLIAIAGAKIWI
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHCCHHHHHHHHHHHHCCEEEE
DNHIDFSKNSNLIIAAVTVIMGTGNFSLHLGGFDLGGIGTATLTAIVLNALFNRQKD
ECCCCCCCCCCEEEEEEEHHEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]