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The map label for this gene is sdaA [H]

Identifier: 93006023

GI number: 93006023

Start: 1447456

End: 1448889

Strand: Reverse

Name: sdaA [H]

Synonym: Pcryo_1195

Alternate gene names: 93006023

Gene position: 1448889-1447456 (Counterclockwise)

Preceding gene: 93006025

Following gene: 93006019

Centisome position: 47.35

GC content: 45.33

Gene sequence:

>1434_bases
ATGATTAGTGTCTTTGATTTATTCAAAATCGGCGTTGGCCCATCAAGCTCTCATACGGTTGGTCCTATGATAGCGGCTAA
CTTGTTTGTACAGTCACTCCTAAAGCAAACCAATCTGAGCGACATCCAGTCTTTAGAGATTGAGTTATATGGCTCGCTTG
CGGCAACTGGTAAAGGACATGCTACAGATACTGCCATATTACTGGGCTTACTTGGTCATGCACCTAGCACCATCGATACG
CGTTTGACCAGTGAATATCTAGCACCGATCTTTTCAGACAATCAACTCAATATCGCAGGCGAGCACGTTATTGCTTTTGA
TACAGAGCGTGATATTCACTGGTATGATGAGACGGTTCTACCTTATCATCCGAATGCTATGACTATTCGTGTGTCTTTGG
CGAATGGCAGCCATTATCAGCAGACTTATTATTCCGTAGGAGGTGGATTTGTTATCAATGAAGAAGATGCGACCAATCCT
GATGAAGATAATGCAACGCCGACTATCGATGTGATTCCTTATCCTTTTAATAGCGCCGCAGAGCTATTAGAACAATGCCG
TAAACATCACTTGAGCGTGAGCGAGCTGGTATTAGCAAACGAATGCCATTACCGTGAGCAGGCAGAAGTATTTGCGTATT
TAGATTCTATTTGGGAGTCGATGCAAGATTGTGTGACCCGTGGCTGCCAAAACAGCGGTATTTTACCGGGTGGCTTAGAT
GTGAGACGCCGTGCTCAAGCATTATACGTGCAACTGTGTGCTGAAAAAGATCAGCCGATTGCGCAAAATGACAAATTGGT
TGCGATGGATTGGATTGATTTATATGCTTTAGCAGTCAATGAAGAAAACGCCAATGGCGGCAATGTGGTCACCGCTCCTA
CCAACGGCGCCGCAGGTATCATTCCTGCAGTGATGCATTATTATCGCGATTTTTTATCAAACTATAGCCTTGATGGCGCG
CGCAAGTTTTTGTTAAATGCCACAGCAATTGGCAGCTTAATCAAACAAAACGCTTCAATATCGGGTGCTGAAGTTGGCTG
TCAAGGTGAAGTCGGTTCAGCTTGTGCAATGGCGGCGTCTGCATTGGCAGAAATCCTAGGCGGAGATCCTGCTAAATGTC
TTAATGCTGCTGAGATTGGTATCGAGCATAACTTGGGTCTGACCTGTGATCCTGTTGGTGGCTTAGTCCAAGTCCCTTGT
ATCGAGCGCAATGCGATGGGCGCAGTCAAAGCAGTCAATGCTGCACGACTTGCCTGTCGTGGTAACGGTCAACATTTTGT
CTCTTTAGACAAAGTCATTGAAACTATGAAAGTTACTGGTGCTGACATGTTAGATAAATACAAAGAAACTTCTCGCGGTG
GATTGGCAGTATATGCTGACAACCGTATACCGACTGCCACTCATGGCGTCAGCGTAAAATACAGCCAGTGCTAA

Upstream 100 bases:

>100_bases
GATACTTATTATCTATTGTTGCCCGTTATAATTTTATATGGGCGCAGTAGTCTTTGCTATGCGGTTTTTCTGAATCCCTT
TTATTTTTTGGTAACTTATT

Downstream 100 bases:

>100_bases
TGATTGGGCAGCTTATAATTCAATAGAACATATAAAACCTATTATAAAAAAAGACCTCTAATCATTAGAGGTCTTTTTTT
GAGCTAACTACTATTGAACT

Product: L-serine dehydratase 1

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MISVFDLFKIGVGPSSSHTVGPMIAANLFVQSLLKQTNLSDIQSLEIELYGSLAATGKGHATDTAILLGLLGHAPSTIDT
RLTSEYLAPIFSDNQLNIAGEHVIAFDTERDIHWYDETVLPYHPNAMTIRVSLANGSHYQQTYYSVGGGFVINEEDATNP
DEDNATPTIDVIPYPFNSAAELLEQCRKHHLSVSELVLANECHYREQAEVFAYLDSIWESMQDCVTRGCQNSGILPGGLD
VRRRAQALYVQLCAEKDQPIAQNDKLVAMDWIDLYALAVNEENANGGNVVTAPTNGAAGIIPAVMHYYRDFLSNYSLDGA
RKFLLNATAIGSLIKQNASISGAEVGCQGEVGSACAMAASALAEILGGDPAKCLNAAEIGIEHNLGLTCDPVGGLVQVPC
IERNAMGAVKAVNAARLACRGNGQHFVSLDKVIETMKVTGADMLDKYKETSRGGLAVYADNRIPTATHGVSVKYSQC

Sequences:

>Translated_477_residues
MISVFDLFKIGVGPSSSHTVGPMIAANLFVQSLLKQTNLSDIQSLEIELYGSLAATGKGHATDTAILLGLLGHAPSTIDT
RLTSEYLAPIFSDNQLNIAGEHVIAFDTERDIHWYDETVLPYHPNAMTIRVSLANGSHYQQTYYSVGGGFVINEEDATNP
DEDNATPTIDVIPYPFNSAAELLEQCRKHHLSVSELVLANECHYREQAEVFAYLDSIWESMQDCVTRGCQNSGILPGGLD
VRRRAQALYVQLCAEKDQPIAQNDKLVAMDWIDLYALAVNEENANGGNVVTAPTNGAAGIIPAVMHYYRDFLSNYSLDGA
RKFLLNATAIGSLIKQNASISGAEVGCQGEVGSACAMAASALAEILGGDPAKCLNAAEIGIEHNLGLTCDPVGGLVQVPC
IERNAMGAVKAVNAARLACRGNGQHFVSLDKVIETMKVTGADMLDKYKETSRGGLAVYADNRIPTATHGVSVKYSQC
>Mature_477_residues
MISVFDLFKIGVGPSSSHTVGPMIAANLFVQSLLKQTNLSDIQSLEIELYGSLAATGKGHATDTAILLGLLGHAPSTIDT
RLTSEYLAPIFSDNQLNIAGEHVIAFDTERDIHWYDETVLPYHPNAMTIRVSLANGSHYQQTYYSVGGGFVINEEDATNP
DEDNATPTIDVIPYPFNSAAELLEQCRKHHLSVSELVLANECHYREQAEVFAYLDSIWESMQDCVTRGCQNSGILPGGLD
VRRRAQALYVQLCAEKDQPIAQNDKLVAMDWIDLYALAVNEENANGGNVVTAPTNGAAGIIPAVMHYYRDFLSNYSLDGA
RKFLLNATAIGSLIKQNASISGAEVGCQGEVGSACAMAASALAEILGGDPAKCLNAAEIGIEHNLGLTCDPVGGLVQVPC
IERNAMGAVKAVNAARLACRGNGQHFVSLDKVIETMKVTGADMLDKYKETSRGGLAVYADNRIPTATHGVSVKYSQC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=458, Percent_Identity=50.8733624454148, Blast_Score=447, Evalue=1e-127,
Organism=Escherichia coli, GI1788116, Length=458, Percent_Identity=49.7816593886463, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI48994925, Length=458, Percent_Identity=51.7467248908297, Blast_Score=444, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 51157; Mature: 51157

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVFDLFKIGVGPSSSHTVGPMIAANLFVQSLLKQTNLSDIQSLEIELYGSLAATGKGH
CCCCEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHEEEEEEEEEEEECCCCC
ATDTAILLGLLGHAPSTIDTRLTSEYLAPIFSDNQLNIAGEHVIAFDTERDIHWYDETVL
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCEEECCEEC
PYHPNAMTIRVSLANGSHYQQTYYSVGGGFVINEEDATNPDEDNATPTIDVIPYPFNSAA
CCCCCEEEEEEEECCCCCHHHHHHCCCCCEEECCCCCCCCCCCCCCCEEEEEECCCCHHH
ELLEQCRKHHLSVSELVLANECHYREQAEVFAYLDSIWESMQDCVTRGCQNSGILPGGLD
HHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
VRRRAQALYVQLCAEKDQPIAQNDKLVAMDWIDLYALAVNEENANGGNVVTAPTNGAAGI
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEEEEECCCCCCCEEEECCCCCCCHH
IPAVMHYYRDFLSNYSLDGARKFLLNATAIGSLIKQNASISGAEVGCQGEVGSACAMAAS
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
ALAEILGGDPAKCLNAAEIGIEHNLGLTCDPVGGLVQVPCIERNAMGAVKAVNAARLACR
HHHHHHCCCHHHHHHHHHCCEECCCCEEECCCCCEEECCCCCCCCCCHHHHHHHHEEEEC
GNGQHFVSLDKVIETMKVTGADMLDKYKETSRGGLAVYADNRIPTATHGVSVKYSQC
CCCCEEEEHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEECCC
>Mature Secondary Structure
MISVFDLFKIGVGPSSSHTVGPMIAANLFVQSLLKQTNLSDIQSLEIELYGSLAATGKGH
CCCCEEEHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHEEEEEEEEEEEECCCCC
ATDTAILLGLLGHAPSTIDTRLTSEYLAPIFSDNQLNIAGEHVIAFDTERDIHWYDETVL
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCEEECCEEC
PYHPNAMTIRVSLANGSHYQQTYYSVGGGFVINEEDATNPDEDNATPTIDVIPYPFNSAA
CCCCCEEEEEEEECCCCCHHHHHHCCCCCEEECCCCCCCCCCCCCCCEEEEEECCCCHHH
ELLEQCRKHHLSVSELVLANECHYREQAEVFAYLDSIWESMQDCVTRGCQNSGILPGGLD
HHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
VRRRAQALYVQLCAEKDQPIAQNDKLVAMDWIDLYALAVNEENANGGNVVTAPTNGAAGI
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEEEEEECCCCCCCEEEECCCCCCCHH
IPAVMHYYRDFLSNYSLDGARKFLLNATAIGSLIKQNASISGAEVGCQGEVGSACAMAAS
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
ALAEILGGDPAKCLNAAEIGIEHNLGLTCDPVGGLVQVPCIERNAMGAVKAVNAARLACR
HHHHHHCCCHHHHHHHHHCCEECCCCEEECCCCCEEECCCCCCCCCCHHHHHHHHEEEEC
GNGQHFVSLDKVIETMKVTGADMLDKYKETSRGGLAVYADNRIPTATHGVSVKYSQC
CCCCEEEEHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]