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The map label for this gene is hit [H]

Identifier: 93005904

GI number: 93005904

Start: 1295997

End: 1296437

Strand: Direct

Name: hit [H]

Synonym: Pcryo_1076

Alternate gene names: 93005904

Gene position: 1295997-1296437 (Clockwise)

Preceding gene: 93005900

Following gene: 93005905

Centisome position: 42.35

GC content: 43.31

Gene sequence:

>441_bases
ATGAGCCAAGCCAATCCGCAAACTACTTATAAAGACGATAATATTTTTGCCAAAATGCTCGATGGCGATATCCCTTATCA
TAAAGTTTATGAAGATGATAAGACTCTTGCTTTTATGGATATCATGCCACAAGCAAAGGGGCATGTTTTGGTCATTCCTA
AGCAAAAAGCGGTGGACTTAGCTGATCTTGAACCTGAATATGCGGCAGCTGTGTTGATGACGGCTAAAAAAGTCATGGAA
GCCCAACGTCAGGTATTTAATCGTGAAGGCATTGTCCAAATGCAGCTAAATGGTGCAGAAGCGGGGCAAACGGTGTTTCA
TTATCATGTGCACCTGATTCCTTCTAGTATTCATGAGCTTGGTCGCCATGCCGTCACACAAGCAGATCATGCCGAGCTTG
CAAAAACAGCTGAACAACTGGCAGCGATTATTACTGCGTAA

Upstream 100 bases:

>100_bases
TCGTCCACTATATTTAATGGTGTAAGTATTCGTTTAATACTCGCTATCCAAACAATACTAACTTTGATTCAATAATAATA
CAGGTTAAAGGAATAAGATA

Downstream 100 bases:

>100_bases
TTTTAAAAACGTCTATCGTTGTTCTGAGTTAAAAGAACAGATAGTACTTACTCTTTAGATAATAATAAAAGGGCAACTAA
CAAGTTGCCTTTTTTGTTTT

Product: histidine triad (HIT) protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MSQANPQTTYKDDNIFAKMLDGDIPYHKVYEDDKTLAFMDIMPQAKGHVLVIPKQKAVDLADLEPEYAAAVLMTAKKVME
AQRQVFNREGIVQMQLNGAEAGQTVFHYHVHLIPSSIHELGRHAVTQADHAELAKTAEQLAAIITA

Sequences:

>Translated_146_residues
MSQANPQTTYKDDNIFAKMLDGDIPYHKVYEDDKTLAFMDIMPQAKGHVLVIPKQKAVDLADLEPEYAAAVLMTAKKVME
AQRQVFNREGIVQMQLNGAEAGQTVFHYHVHLIPSSIHELGRHAVTQADHAELAKTAEQLAAIITA
>Mature_145_residues
SQANPQTTYKDDNIFAKMLDGDIPYHKVYEDDKTLAFMDIMPQAKGHVLVIPKQKAVDLADLEPEYAAAVLMTAKKVMEA
QRQVFNREGIVQMQLNGAEAGQTVFHYHVHLIPSSIHELGRHAVTQADHAELAKTAEQLAAIITA

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=103, Percent_Identity=35.9223300970874, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17506713, Length=106, Percent_Identity=34.9056603773585, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320078, Length=132, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574010, Length=105, Percent_Identity=32.3809523809524, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581222, Length=105, Percent_Identity=32.3809523809524, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 16209; Mature: 16078

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQANPQTTYKDDNIFAKMLDGDIPYHKVYEDDKTLAFMDIMPQAKGHVLVIPKQKAVDL
CCCCCCCCCCCCCCHHEEECCCCCCCHHEECCCCEEEEEECCCCCCCCEEEECCCCCCCC
ADLEPEYAAAVLMTAKKVMEAQRQVFNREGIVQMQLNGAEAGQTVFHYHVHLIPSSIHEL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEECHHHHHHH
GRHAVTQADHAELAKTAEQLAAIITA
HHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQANPQTTYKDDNIFAKMLDGDIPYHKVYEDDKTLAFMDIMPQAKGHVLVIPKQKAVDL
CCCCCCCCCCCCCHHEEECCCCCCCHHEECCCCEEEEEECCCCCCCCEEEECCCCCCCC
ADLEPEYAAAVLMTAKKVMEAQRQVFNREGIVQMQLNGAEAGQTVFHYHVHLIPSSIHEL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEECHHHHHHH
GRHAVTQADHAELAKTAEQLAAIITA
HHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]