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The map label for this gene is fadI [H]

Identifier: 93005896

GI number: 93005896

Start: 1284247

End: 1285860

Strand: Reverse

Name: fadI [H]

Synonym: Pcryo_1068

Alternate gene names: 93005896

Gene position: 1285860-1284247 (Counterclockwise)

Preceding gene: 93005901

Following gene: 93005895

Centisome position: 42.02

GC content: 45.23

Gene sequence:

>1614_bases
ATGAGTAACAAAAACAATCATCCAGATAGTCCTATAGTTGAGACCACCGTGGTAAAAGCCAGTGATGCTAAGAGCACCGA
TACTGCTGTAAAATCAGACACCACTGATGCTAAAAAAACAGATGCCAAAGCAGAACCAAAAGCTGATAGCGCTAAAAAAG
ACACCGTAGCAAAAGATAGTAAAACCACTGCTACGAAAGAGGATAACGCAGCTAAAGAAAGTGCGGCAAAAAGTAACAGT
GATAAAAAAGAAGCATCTAAAAAGGCTGACGCGACTCCTGCTAAGAAAACAAATACTGTGGCTAAAAAAGCAAGTACGAC
TAAGCTTAGCTCAGGTCAGAACCGTGTGGCTATCCTAGGTGGCAACCGTATCCCATTTGCTCGCTCAAACGGCTCATATG
CTGATGTTAGCAACACGGATATGCTCACTGCTGCGTTAGATGGTTTGGTCGAGCGTTTTAACTTACAAGATGAAAAAATC
GGTGAAGTCGTTGCTGGTGCAGTTATGAAACTGAGTCGCGATATCAACCTGACTCGTGAAGCGACATTAAATACTGCACT
TAACCCACATACCCCAACGTATGATATCTCTCAAGCTTGTGGTACTGGCTTGCAAGCGACGTTTGCTTCTGCCAATAAAA
TCGCGCTTGGTATCATCGATTCAGCTATTACTGGCGGTGTTGATACTACTTCTGATGCGCCTATCGCAGTCGGCGATGGC
TTACGTAAAGTATTGATTAAATTGGGCGCAGCTAAAGACAATAAACAACGCCTAAAAGCATTGATGGGTCTAAACCCGAA
AGATTTACTTGATACGCCGCAAAATGGTGAGCCACGTACTGGTTTATCCATGGGCGACCATCAAGCGATCACTACGCTAG
AATGGAACATCAGCCGTGAAGCGCAAGATGAGCTTGCCTTCAATAGTCATCAAAACCTAGCACGCGCTTATGACGAAGGT
TTCTTTGATGATTTAATTACCCCATATAAAGGTCTGACCCGCGATAACAACTTGCGTCCAGATACCACTTTAGAGAAGCT
AGCTAAGCTCAAGCCTGTTTTTGGTAAAAAGAATGCCAAGCCAACCATGACTGCTGCTAACTCTACCCCATTGACTGATG
GTGCATCTTGTATCCTATTGGGTACTGATGAGTGGGCGGCAGCACATGGTCTAAAACCATTGGCTTATATCGTCCATCAA
GAAACAGCGGCTGTTGATTTCATCGGTAAATCTGGTGATACAGAAGGCTTGCTCATGGCACCGGCCTATGCCGTACCGCG
TATGCTTGAGCGTGCTGGTTTGACGCTACAAGATTTCGATTTTTATGAAATCCATGAAGCTTTTGCTTCACAAGTATTAT
CAACGCTTGCTGCATGGGAAGACGAGAAGTTCTGTGAAGAGCGTCTAGGTCTTGACGCGCCACTAGGCTCTATCGATCGT
AGTAAGCTAAACGTCAACGGCTCATCACTTGCTGCAGGTCATCCATTTGCTGCAACCGGTGGTCGTATCCTAGCCACTGC
TGCCAAACTATTAGATCAAAAAGGCTCAGGTCGTGCGCTTATCTCTATTTGCGCCGCTGGCGGTCAAGGTGTGACCTGTA
TCTTAGAAAAATAG

Upstream 100 bases:

>100_bases
AGTATTTTAGGTGTTTTTAGAATAAAGACTTCTATTATTTAAATATTTTTTTGATAACTTCCCTCTTCTATTTCTACCCA
TATTTTTTAAGGATAATATT

Downstream 100 bases:

>100_bases
TGATATGTAAATACAACGTGTAAGACTGATGCAGTTTTAAAAATACCCTTTAATCTATTGATTAGAGGGTATTTTTTTAT
CTAAATAAATATTGGCTACT

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: ACSs; Acetyl-CoA acyltransferase; Acyl-CoA ligase; Beta-ketothiolase; Fatty acid oxidation complex subunit beta [H]

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MSNKNNHPDSPIVETTVVKASDAKSTDTAVKSDTTDAKKTDAKAEPKADSAKKDTVAKDSKTTATKEDNAAKESAAKSNS
DKKEASKKADATPAKKTNTVAKKASTTKLSSGQNRVAILGGNRIPFARSNGSYADVSNTDMLTAALDGLVERFNLQDEKI
GEVVAGAVMKLSRDINLTREATLNTALNPHTPTYDISQACGTGLQATFASANKIALGIIDSAITGGVDTTSDAPIAVGDG
LRKVLIKLGAAKDNKQRLKALMGLNPKDLLDTPQNGEPRTGLSMGDHQAITTLEWNISREAQDELAFNSHQNLARAYDEG
FFDDLITPYKGLTRDNNLRPDTTLEKLAKLKPVFGKKNAKPTMTAANSTPLTDGASCILLGTDEWAAAHGLKPLAYIVHQ
ETAAVDFIGKSGDTEGLLMAPAYAVPRMLERAGLTLQDFDFYEIHEAFASQVLSTLAAWEDEKFCEERLGLDAPLGSIDR
SKLNVNGSSLAAGHPFAATGGRILATAAKLLDQKGSGRALISICAAGGQGVTCILEK

Sequences:

>Translated_537_residues
MSNKNNHPDSPIVETTVVKASDAKSTDTAVKSDTTDAKKTDAKAEPKADSAKKDTVAKDSKTTATKEDNAAKESAAKSNS
DKKEASKKADATPAKKTNTVAKKASTTKLSSGQNRVAILGGNRIPFARSNGSYADVSNTDMLTAALDGLVERFNLQDEKI
GEVVAGAVMKLSRDINLTREATLNTALNPHTPTYDISQACGTGLQATFASANKIALGIIDSAITGGVDTTSDAPIAVGDG
LRKVLIKLGAAKDNKQRLKALMGLNPKDLLDTPQNGEPRTGLSMGDHQAITTLEWNISREAQDELAFNSHQNLARAYDEG
FFDDLITPYKGLTRDNNLRPDTTLEKLAKLKPVFGKKNAKPTMTAANSTPLTDGASCILLGTDEWAAAHGLKPLAYIVHQ
ETAAVDFIGKSGDTEGLLMAPAYAVPRMLERAGLTLQDFDFYEIHEAFASQVLSTLAAWEDEKFCEERLGLDAPLGSIDR
SKLNVNGSSLAAGHPFAATGGRILATAAKLLDQKGSGRALISICAAGGQGVTCILEK
>Mature_536_residues
SNKNNHPDSPIVETTVVKASDAKSTDTAVKSDTTDAKKTDAKAEPKADSAKKDTVAKDSKTTATKEDNAAKESAAKSNSD
KKEASKKADATPAKKTNTVAKKASTTKLSSGQNRVAILGGNRIPFARSNGSYADVSNTDMLTAALDGLVERFNLQDEKIG
EVVAGAVMKLSRDINLTREATLNTALNPHTPTYDISQACGTGLQATFASANKIALGIIDSAITGGVDTTSDAPIAVGDGL
RKVLIKLGAAKDNKQRLKALMGLNPKDLLDTPQNGEPRTGLSMGDHQAITTLEWNISREAQDELAFNSHQNLARAYDEGF
FDDLITPYKGLTRDNNLRPDTTLEKLAKLKPVFGKKNAKPTMTAANSTPLTDGASCILLGTDEWAAAHGLKPLAYIVHQE
TAAVDFIGKSGDTEGLLMAPAYAVPRMLERAGLTLQDFDFYEIHEAFASQVLSTLAAWEDEKFCEERLGLDAPLGSIDRS
KLNVNGSSLAAGHPFAATGGRILATAAKLLDQKGSGRALISICAAGGQGVTCILEK

Specific function: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI4504327, Length=428, Percent_Identity=37.8504672897196, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI167614485, Length=430, Percent_Identity=29.0697674418605, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI4501853, Length=436, Percent_Identity=29.5871559633028, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI148539872, Length=439, Percent_Identity=26.879271070615, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI4557237, Length=433, Percent_Identity=28.6374133949192, Blast_Score=145, Evalue=6e-35,
Organism=Escherichia coli, GI1788683, Length=430, Percent_Identity=39.0697674418605, Blast_Score=278, Evalue=8e-76,
Organism=Escherichia coli, GI1787663, Length=435, Percent_Identity=32.4137931034483, Blast_Score=166, Evalue=5e-42,
Organism=Escherichia coli, GI87082165, Length=434, Percent_Identity=28.8018433179723, Blast_Score=156, Evalue=4e-39,
Organism=Escherichia coli, GI1788554, Length=437, Percent_Identity=29.2906178489703, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI48994986, Length=435, Percent_Identity=27.816091954023, Blast_Score=138, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17551802, Length=429, Percent_Identity=36.3636363636364, Blast_Score=255, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI133906874, Length=432, Percent_Identity=28.7037037037037, Blast_Score=161, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI17535921, Length=434, Percent_Identity=27.6497695852535, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI25147385, Length=447, Percent_Identity=26.6219239373602, Blast_Score=135, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6322031, Length=460, Percent_Identity=29.5652173913043, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6325229, Length=446, Percent_Identity=27.5784753363229, Blast_Score=150, Evalue=4e-37,
Organism=Drosophila melanogaster, GI17137578, Length=439, Percent_Identity=36.9020501138952, Blast_Score=252, Evalue=4e-67,
Organism=Drosophila melanogaster, GI24655093, Length=434, Percent_Identity=27.6497695852535, Blast_Score=166, Evalue=5e-41,
Organism=Drosophila melanogaster, GI17648125, Length=449, Percent_Identity=30.0668151447661, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24640423, Length=440, Percent_Identity=26.1363636363636, Blast_Score=140, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012806
- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.16 [H]

Molecular weight: Translated: 56773; Mature: 56642

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKNNHPDSPIVETTVVKASDAKSTDTAVKSDTTDAKKTDAKAEPKADSAKKDTVAKDS
CCCCCCCCCCCCEEEEEEECCCCCCCCCHHCCCCCCCHHCCCCCCCCCCCCHHHHHCCCC
KTTATKEDNAAKESAAKSNSDKKEASKKADATPAKKTNTVAKKASTTKLSSGQNRVAILG
CCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCHHHCCCCCCEEEEEE
GNRIPFARSNGSYADVSNTDMLTAALDGLVERFNLQDEKIGEVVAGAVMKLSRDINLTRE
CCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHH
ATLNTALNPHTPTYDISQACGTGLQATFASANKIALGIIDSAITGGVDTTSDAPIAVGDG
HHHHCCCCCCCCCCCHHHHHCCCCEEHHCCCCEEEEEEHHHHHCCCCCCCCCCCEEHHHH
LRKVLIKLGAAKDNKQRLKALMGLNPKDLLDTPQNGEPRTGLSMGDHQAITTLEWNISRE
HHHHHHHHCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCH
AQDELAFNSHQNLARAYDEGFFDDLITPYKGLTRDNNLRPDTTLEKLAKLKPVFGKKNAK
HHHHHHHCCHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
PTMTAANSTPLTDGASCILLGTDEWAAAHGLKPLAYIVHQETAAVDFIGKSGDTEGLLMA
CCEEECCCCCCCCCCCEEEEECCHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCCEEEC
PAYAVPRMLERAGLTLQDFDFYEIHEAFASQVLSTLAAWEDEKFCEERLGLDAPLGSIDR
CHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCC
SKLNVNGSSLAAGHPFAATGGRILATAAKLLDQKGSGRALISICAAGGQGVTCILEK
CEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEC
>Mature Secondary Structure 
SNKNNHPDSPIVETTVVKASDAKSTDTAVKSDTTDAKKTDAKAEPKADSAKKDTVAKDS
CCCCCCCCCCCEEEEEEECCCCCCCCCHHCCCCCCCHHCCCCCCCCCCCCHHHHHCCCC
KTTATKEDNAAKESAAKSNSDKKEASKKADATPAKKTNTVAKKASTTKLSSGQNRVAILG
CCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHCCHHHCCCCCCEEEEEE
GNRIPFARSNGSYADVSNTDMLTAALDGLVERFNLQDEKIGEVVAGAVMKLSRDINLTRE
CCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHH
ATLNTALNPHTPTYDISQACGTGLQATFASANKIALGIIDSAITGGVDTTSDAPIAVGDG
HHHHCCCCCCCCCCCHHHHHCCCCEEHHCCCCEEEEEEHHHHHCCCCCCCCCCCEEHHHH
LRKVLIKLGAAKDNKQRLKALMGLNPKDLLDTPQNGEPRTGLSMGDHQAITTLEWNISRE
HHHHHHHHCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCH
AQDELAFNSHQNLARAYDEGFFDDLITPYKGLTRDNNLRPDTTLEKLAKLKPVFGKKNAK
HHHHHHHCCHHHHHHHHHHHHHHHHHCHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
PTMTAANSTPLTDGASCILLGTDEWAAAHGLKPLAYIVHQETAAVDFIGKSGDTEGLLMA
CCEEECCCCCCCCCCCEEEEECCHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCCEEEC
PAYAVPRMLERAGLTLQDFDFYEIHEAFASQVLSTLAAWEDEKFCEERLGLDAPLGSIDR
CHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCC
SKLNVNGSSLAAGHPFAATGGRILATAAKLLDQKGSGRALISICAAGGQGVTCILEK
CEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA