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The map label for this gene is pdxH [H]

Identifier: 93005835

GI number: 93005835

Start: 1205243

End: 1205893

Strand: Direct

Name: pdxH [H]

Synonym: Pcryo_1007

Alternate gene names: 93005835

Gene position: 1205243-1205893 (Clockwise)

Preceding gene: 93005834

Following gene: 93005843

Centisome position: 39.39

GC content: 43.78

Gene sequence:

>651_bases
ATGAGTATGGATTTTAGCGATCAGCGTTTGTCATATGAAAAAGGTCAACTAGACCAACAATCAATACCAGCATCACCGTT
TGAGCTGTTAAATGTTTGGATGCAGCAGGCCATAGAAGAAAACGTGCAAGAGCCGTATGCTATGAGCTTAGCGACTTGTG
GGGCGGATAATAAGCCTAGCGTGCGTATTGTTCTATTGCGTGAGATTACAGATAAAGGTATCGTTTTTTATACCAATTAC
GAAAGTGCCAAGGGTCAAGATATCGCTGAAAATCCTAATGTCGAAGCGCTGTTTTTTTGGCATAAGCTTGAGCGTCAGAT
TCGTATTAGCGGCAGTATTGCTAAAATTGATGCTGATAAATCTGCTGCTTACTTTCAAAAACGCCCGCACGATAGCCAAG
TAGGCGCATGGGTTAGCCAACCACAAAGCGGTGAAGTTGCTAATCGCGATGTGATGGAGCAGACGTTTGAGCAATTGAAA
ATAGACTATCCAGAAGGTGCAGCCGTACCAACGCCTGAGTTTTGGGGTGGTTACGAGATTACTGTCAATGAGATTGAGTT
TTGGCAAGGTCGCGCCAATCGAATGCATGACCGTATTGTCTATCATAAAGAGGCGGATGGTAGTTTTAGCACCAAACGCT
TATTGCCTTAA

Upstream 100 bases:

>100_bases
TGTGATGTAATGGCGAATGATTTGGCAGATAAAATAAAAGCCATATTGGGTTAATAGTCTTTGATATAAACATACTAGAA
TAGCAAAATAAGGGACAATC

Downstream 100 bases:

>100_bases
ACGTAATCAATAGCGCATGATATGGGCTTAGAAGAAGTTCATGTTTATAAAAAAGCCACTTTACCTGTCGTATTCATATG
GCAAAAAAAGTGGCTTTTTT

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSMDFSDQRLSYEKGQLDQQSIPASPFELLNVWMQQAIEENVQEPYAMSLATCGADNKPSVRIVLLREITDKGIVFYTNY
ESAKGQDIAENPNVEALFFWHKLERQIRISGSIAKIDADKSAAYFQKRPHDSQVGAWVSQPQSGEVANRDVMEQTFEQLK
IDYPEGAAVPTPEFWGGYEITVNEIEFWQGRANRMHDRIVYHKEADGSFSTKRLLP

Sequences:

>Translated_216_residues
MSMDFSDQRLSYEKGQLDQQSIPASPFELLNVWMQQAIEENVQEPYAMSLATCGADNKPSVRIVLLREITDKGIVFYTNY
ESAKGQDIAENPNVEALFFWHKLERQIRISGSIAKIDADKSAAYFQKRPHDSQVGAWVSQPQSGEVANRDVMEQTFEQLK
IDYPEGAAVPTPEFWGGYEITVNEIEFWQGRANRMHDRIVYHKEADGSFSTKRLLP
>Mature_215_residues
SMDFSDQRLSYEKGQLDQQSIPASPFELLNVWMQQAIEENVQEPYAMSLATCGADNKPSVRIVLLREITDKGIVFYTNYE
SAKGQDIAENPNVEALFFWHKLERQIRISGSIAKIDADKSAAYFQKRPHDSQVGAWVSQPQSGEVANRDVMEQTFEQLKI
DYPEGAAVPTPEFWGGYEITVNEIEFWQGRANRMHDRIVYHKEADGSFSTKRLLP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=206, Percent_Identity=36.4077669902913, Blast_Score=149, Evalue=1e-36,
Organism=Escherichia coli, GI1787926, Length=208, Percent_Identity=42.7884615384615, Blast_Score=184, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17553712, Length=224, Percent_Identity=39.2857142857143, Blast_Score=154, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6319509, Length=216, Percent_Identity=33.3333333333333, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI45551845, Length=180, Percent_Identity=40, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24644901, Length=180, Percent_Identity=40, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24644903, Length=179, Percent_Identity=27.3743016759777, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 24684; Mature: 24553

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMDFSDQRLSYEKGQLDQQSIPASPFELLNVWMQQAIEENVQEPYAMSLATCGADNKPS
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCC
VRIVLLREITDKGIVFYTNYESAKGQDIAENPNVEALFFWHKLERQIRISGSIAKIDADK
EEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEHHHHHEEECCCEEEECCCC
SAAYFQKRPHDSQVGAWVSQPQSGEVANRDVMEQTFEQLKIDYPEGAAVPTPEFWGGYEI
CHHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEE
TVNEIEFWQGRANRMHDRIVYHKEADGSFSTKRLLP
EEECEEECCCHHHHHHHHEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
SMDFSDQRLSYEKGQLDQQSIPASPFELLNVWMQQAIEENVQEPYAMSLATCGADNKPS
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCC
VRIVLLREITDKGIVFYTNYESAKGQDIAENPNVEALFFWHKLERQIRISGSIAKIDADK
EEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEHHHHHEEECCCEEEECCCC
SAAYFQKRPHDSQVGAWVSQPQSGEVANRDVMEQTFEQLKIDYPEGAAVPTPEFWGGYEI
CHHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEE
TVNEIEFWQGRANRMHDRIVYHKEADGSFSTKRLLP
EEECEEECCCHHHHHHHHEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA