BacMap

Definition	Psychrobacter cryohalolentis K5 chromosome, complete genome.
Accession	NC_007969
Length	3,059,876

Click here to switch to the map view.

The map label for this gene is gra-orf6 [H]

Identifier: 93005823

GI number: 93005823

Start: 1186876

End: 1187679

Strand: Reverse

Name: gra-orf6 [H]

Synonym: Pcryo_0995

Alternate gene names: 93005823

Gene position: 1187679-1186876 (Counterclockwise)

Preceding gene: 93005824

Following gene: 93005822

Centisome position: 38.81

GC content: 45.9

Gene sequence:

>804_bases
ATGAATCAAAAAACTAAAACTTCTCAGCCAATTGATACTCATGCCCCTGTTATGCTTGTGACTGGTAGCGCTAAGCGTAT
CGGTGCTGCAATTGTTCGTGCGGCTCACAAGCAAGGCTATCGCGTCATTATCCATTGTCATCATAGTGAGCAAGAGGCAC
ATGCATTAGCAGACGTGCTGAATGATACTTGCGCTCATAGTGCTGTGGTTATTGTCGCGGATTTGGCAGTGGTAAATCAG
GCAGACACTCTCAAGCACCTGACCCAAACTATCATGCAGGCATTTGGGCAACTAAACGTACTGGTACATAATGCCTCTCG
CTTTTACTCTACTCCCCTTGGCAGTATTAATTATGACCAGTGGGATGAGCTGCTGTTGACCAATGCCAAAGCGCCTTTGT
TGTTAAGCCAAGCACTACTACCTTATCTTAAGCAACAACAAGGTTGTATTATTAGTTTGCTCGATATTCATGCACAGGAT
AAGCCGTTCGCCAATTATACGGTTTACAATATGGCAAAAGCGGCCCATCGGATGATGGTGCAGTCTTTAGCACTGGATAT
GGCGCCTGATGTACGCGTTAATGGGGTCGCGCCTGGGGTCAATATTTTACCCAATACAGATAGCGATCAAGCGCTTGATA
GTCAACAGCAAAGTAAGATTATAGGTTCCATTCCTATGCAGCGAATAGGTATCCCTGCTGACATTGCGCATAGCGTGCTC
TATTTGGCGAATGCCAGTTATGTGACGGGTGAAATAATAACCGTAGATGGAGGCCGAAGTTTGACGCTGGCTGGTGGTAA
TTAG

Upstream 100 bases:

>100_bases
TCAATGCAGAATTGAGCATTTACAAACGCAAACAGCCTGACTAAAAATAGAGTAAATGACCTTTTAAAACTTAAAAATAT
ATCCTGATTAAAATGCTACT

Downstream 100 bases:

>100_bases
TGATAATTCATTAAATAGTATGCCCTATCTGCTAACTTTTACTTGAAAATATATAAAAATCAGGTATCATTGTGCGTCTA
AAGGGCCCATAGCTCAGTTG

Product: pteridine reductase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: ORF6 [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MNQKTKTSQPIDTHAPVMLVTGSAKRIGAAIVRAAHKQGYRVIIHCHHSEQEAHALADVLNDTCAHSAVVIVADLAVVNQ
ADTLKHLTQTIMQAFGQLNVLVHNASRFYSTPLGSINYDQWDELLLTNAKAPLLLSQALLPYLKQQQGCIISLLDIHAQD
KPFANYTVYNMAKAAHRMMVQSLALDMAPDVRVNGVAPGVNILPNTDSDQALDSQQQSKIIGSIPMQRIGIPADIAHSVL
YLANASYVTGEIITVDGGRSLTLAGGN

Sequences:

>Translated_267_residues
MNQKTKTSQPIDTHAPVMLVTGSAKRIGAAIVRAAHKQGYRVIIHCHHSEQEAHALADVLNDTCAHSAVVIVADLAVVNQ
ADTLKHLTQTIMQAFGQLNVLVHNASRFYSTPLGSINYDQWDELLLTNAKAPLLLSQALLPYLKQQQGCIISLLDIHAQD
KPFANYTVYNMAKAAHRMMVQSLALDMAPDVRVNGVAPGVNILPNTDSDQALDSQQQSKIIGSIPMQRIGIPADIAHSVL
YLANASYVTGEIITVDGGRSLTLAGGN
>Mature_267_residues
MNQKTKTSQPIDTHAPVMLVTGSAKRIGAAIVRAAHKQGYRVIIHCHHSEQEAHALADVLNDTCAHSAVVIVADLAVVNQ
ADTLKHLTQTIMQAFGQLNVLVHNASRFYSTPLGSINYDQWDELLLTNAKAPLLLSQALLPYLKQQQGCIISLLDIHAQD
KPFANYTVYNMAKAAHRMMVQSLALDMAPDVRVNGVAPGVNILPNTDSDQALDSQQQSKIIGSIPMQRIGIPADIAHSVL
YLANASYVTGEIITVDGGRSLTLAGGN

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=28.3400809716599, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=31.496062992126, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=31.4516129032258, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=27.2, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI33667109, Length=187, Percent_Identity=31.5508021390374, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI10190704, Length=259, Percent_Identity=27.7992277992278, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI59889578, Length=243, Percent_Identity=31.2757201646091, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=27.3092369477912, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=26.5193370165746, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=29.9212598425197, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=28.968253968254, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1786812, Length=264, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=24.2914979757085, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=27.0161290322581, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=31.2, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789208, Length=196, Percent_Identity=27.5510204081633, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=26.7716535433071, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI2367175, Length=253, Percent_Identity=25.6916996047431, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=28.7449392712551, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI1787891, Length=248, Percent_Identity=26.6129032258064, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=27.4809160305344, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=27.7777777777778, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=27.2727272727273, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=29.5275590551181, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=30.5220883534137, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=26.6666666666667, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=29.1512915129151, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=264, Percent_Identity=26.8939393939394, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=28.030303030303, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=28.8461538461538, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=271, Percent_Identity=26.5682656826568, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=28.4090909090909, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=30.4, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=28.9156626506024, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=28.7878787878788, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=269, Percent_Identity=29.368029739777, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=25.9398496240602, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=270, Percent_Identity=29.2592592592593, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=29.0076335877863, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=26.8199233716475, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=26.4150943396226, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=28.8888888888889, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=26.615969581749, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=27.3469387755102, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=261, Percent_Identity=29.1187739463602, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=217, Percent_Identity=25.8064516129032, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=32.8, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=30.8880308880309, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=29.2, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=27.8884462151394, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24644337, Length=171, Percent_Identity=34.5029239766082, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=26.8482490272374, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24643142, Length=255, Percent_Identity=28.2352941176471, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 28785; Mature: 28785

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQKTKTSQPIDTHAPVMLVTGSAKRIGAAIVRAAHKQGYRVIIHCHHSEQEAHALADVL
CCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHH
NDTCAHSAVVIVADLAVVNQADTLKHLTQTIMQAFGQLNVLVHNASRFYSTPLGSINYDQ
HHHHHHHHHHEEHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEECCHHHHCCCCCCCCHHH
WDELLLTNAKAPLLLSQALLPYLKQQQGCIISLLDIHAQDKPFANYTVYNMAKAAHRMMV
HHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
QSLALDMAPDVRVNGVAPGVNILPNTDSDQALDSQQQSKIIGSIPMQRIGIPADIAHSVL
HHHHHHCCCCCEEECCCCCCEECCCCCCHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHH
YLANASYVTGEIITVDGGRSLTLAGGN
HHHCCCEEEEEEEEECCCCEEEEECCC
>Mature Secondary Structure
MNQKTKTSQPIDTHAPVMLVTGSAKRIGAAIVRAAHKQGYRVIIHCHHSEQEAHALADVL
CCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHH
NDTCAHSAVVIVADLAVVNQADTLKHLTQTIMQAFGQLNVLVHNASRFYSTPLGSINYDQ
HHHHHHHHHHEEHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEECCHHHHCCCCCCCCHHH
WDELLLTNAKAPLLLSQALLPYLKQQQGCIISLLDIHAQDKPFANYTVYNMAKAAHRMMV
HHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
QSLALDMAPDVRVNGVAPGVNILPNTDSDQALDSQQQSKIIGSIPMQRIGIPADIAHSVL
HHHHHHCCCCCEEECCCCCCEECCCCCCHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHH
YLANASYVTGEIITVDGGRSLTLAGGN
HHHCCCEEEEEEEEECCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2583128; 9831526 [H]