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The map label for this gene is lpxH [H]

Identifier: 93005493

GI number: 93005493

Start: 785926

End: 786774

Strand: Reverse

Name: lpxH [H]

Synonym: Pcryo_0663

Alternate gene names: 93005493

Gene position: 786774-785926 (Counterclockwise)

Preceding gene: 93005494

Following gene: 93005489

Centisome position: 25.71

GC content: 41.22

Gene sequence:

>849_bases
ATGCAAAGTTTCAGCCATCTAATTACCACCCGCCCTCATGAGGTGCGACAAGTATTGATTAGCGATTTGCATTTATCGCC
TGAAGAGCCTGCCTTAGTGCAGGCTTTTTTGGCGCTGCTTGATGATTGCCTTGCTCTGCCTGCGCTAAAACGCCTATTTA
TATTAGGTGACTGGTTTGAAGTCTGGCTTGGGGATGATTTTTATTTGTCTTTATCCGAAGAGGAACGACAAAAACATTGG
CTCACACCACTTATCATTAAATTAAAAAAACTGCGCATAGCTGGCTGCGAGATTTTGGTCATGCACGGCAACCGCGATTT
TTTGTTAGGGCAGCCATTTTGTAATATATTCGGTGGCGAGCTTATTTATGAGCCGTATACATTAACCGTTGGACAGCAAA
ACTATCGCTTAGAACACGGTGATGCACTATGCGTTGATGACAAAAAGTATCAGTTTTTTCGTAAAGTAATGCGTAATCGT
TTGACGCAGTGGTATTTGCTTAATAAATCGTTAGAGAAACGCTTGGCGATTGCTGATAATATGCGGCAAAAGAGTCAGCA
AAATAATGCCAATAAAGCGGCTCATATCATGGATGTTAATGAAGCAGCAGTGAATAAAGCTATTTATCGCTTTGACGCTC
TACTACATGGTCATACCCATCGTCCTGAAATCCACCAAAGTAATGAGGGTAAAACTCGCTATGTCCTTGGTGATTGGCGA
CTGTTAAATAAGGACAAGCGACAGCAAAAAGTGAGTGCCGTGATTGGTGCGATTACAGCAAGCGTAGATGAAGGTATTAT
TGCTGAGAGTGCAGAGTTTAACTTATTTGAATTTAACATTACTATTTAA

Upstream 100 bases:

>100_bases
CATCACTCAGTAATCATTCTTCAATAGTTATTACTCAGTAGCGATGAATCAGTGAAAGCTTATGAGTCGTTACTGTTTAA
AGTTATGAGGATAAGGATAA

Downstream 100 bases:

>100_bases
ATACCTAAACATCAAAACTGCTGCTGTTATCCTTATACAATGAAAAACTCCGTTATAAAACGGAGTTTTTTTTATTTAGT
AACATCGTTATTTTTAAACA

Product: UDP-2,3-diacylglucosamine hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MQSFSHLITTRPHEVRQVLISDLHLSPEEPALVQAFLALLDDCLALPALKRLFILGDWFEVWLGDDFYLSLSEEERQKHW
LTPLIIKLKKLRIAGCEILVMHGNRDFLLGQPFCNIFGGELIYEPYTLTVGQQNYRLEHGDALCVDDKKYQFFRKVMRNR
LTQWYLLNKSLEKRLAIADNMRQKSQQNNANKAAHIMDVNEAAVNKAIYRFDALLHGHTHRPEIHQSNEGKTRYVLGDWR
LLNKDKRQQKVSAVIGAITASVDEGIIAESAEFNLFEFNITI

Sequences:

>Translated_282_residues
MQSFSHLITTRPHEVRQVLISDLHLSPEEPALVQAFLALLDDCLALPALKRLFILGDWFEVWLGDDFYLSLSEEERQKHW
LTPLIIKLKKLRIAGCEILVMHGNRDFLLGQPFCNIFGGELIYEPYTLTVGQQNYRLEHGDALCVDDKKYQFFRKVMRNR
LTQWYLLNKSLEKRLAIADNMRQKSQQNNANKAAHIMDVNEAAVNKAIYRFDALLHGHTHRPEIHQSNEGKTRYVLGDWR
LLNKDKRQQKVSAVIGAITASVDEGIIAESAEFNLFEFNITI
>Mature_282_residues
MQSFSHLITTRPHEVRQVLISDLHLSPEEPALVQAFLALLDDCLALPALKRLFILGDWFEVWLGDDFYLSLSEEERQKHW
LTPLIIKLKKLRIAGCEILVMHGNRDFLLGQPFCNIFGGELIYEPYTLTVGQQNYRLEHGDALCVDDKKYQFFRKVMRNR
LTQWYLLNKSLEKRLAIADNMRQKSQQNNANKAAHIMDVNEAAVNKAIYRFDALLHGHTHRPEIHQSNEGKTRYVLGDWR
LLNKDKRQQKVSAVIGAITASVDEGIIAESAEFNLFEFNITI

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP [H]

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family [H]

Homologues:

Organism=Escherichia coli, GI1786735, Length=229, Percent_Identity=37.9912663755458, Blast_Score=132, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR010138 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: 3.6.1.-

Molecular weight: Translated: 32617; Mature: 32617

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSFSHLITTRPHEVRQVLISDLHLSPEEPALVQAFLALLDDCLALPALKRLFILGDWFE
CCCHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VWLGDDFYLSLSEEERQKHWLTPLIIKLKKLRIAGCEILVMHGNRDFLLGQPFCNIFGGE
HHCCCCEEEECCHHHHHHHHHHHHHHHHHHHEEECEEEEEEECCCCEEECCCHHHHCCCC
LIYEPYTLTVGQQNYRLEHGDALCVDDKKYQFFRKVMRNRLTQWYLLNKSLEKRLAIADN
EEECCEEEEECCCCEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRQKSQQNNANKAAHIMDVNEAAVNKAIYRFDALLHGHTHRPEIHQSNEGKTRYVLGDWR
HHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECEE
LLNKDKRQQKVSAVIGAITASVDEGIIAESAEFNLFEFNITI
ECCCHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEEEEEC
>Mature Secondary Structure
MQSFSHLITTRPHEVRQVLISDLHLSPEEPALVQAFLALLDDCLALPALKRLFILGDWFE
CCCHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VWLGDDFYLSLSEEERQKHWLTPLIIKLKKLRIAGCEILVMHGNRDFLLGQPFCNIFGGE
HHCCCCEEEECCHHHHHHHHHHHHHHHHHHHEEECEEEEEEECCCCEEECCCHHHHCCCC
LIYEPYTLTVGQQNYRLEHGDALCVDDKKYQFFRKVMRNRLTQWYLLNKSLEKRLAIADN
EEECCEEEEECCCCEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRQKSQQNNANKAAHIMDVNEAAVNKAIYRFDALLHGHTHRPEIHQSNEGKTRYVLGDWR
HHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECEE
LLNKDKRQQKVSAVIGAITASVDEGIIAESAEFNLFEFNITI
ECCCHHHHHHHHHHHHHHHHHCCCCCEECCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA