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The map label for this gene is gntR [H]

Identifier: 92115331

GI number: 92115331

Start: 3584488

End: 3585534

Strand: Direct

Name: gntR [H]

Synonym: Csal_3216

Alternate gene names: 92115331

Gene position: 3584488-3585534 (Clockwise)

Preceding gene: 92115325

Following gene: 92115332

Centisome position: 96.97

GC content: 58.55

Gene sequence:

>1047_bases
ATGGCAAACGAGAAGCCATCACCGCGGGGTAGACGCCGCCATCATGGCGACAACCGAGTCACCATCGACGATGTGGCAAA
AGAAGCTGGGGTGGCCCCGATTACGGTGTCTCGAGCTTTGAACACGCCTGATAAGGTGTCGGCCAAACTACGCGAACGTG
TCGATCAAGCAGTGACGTCACTGGGCTATGTCCCCAACCTCATCGCCGGAGGTCTCGCATCAGCGGGTACGCGAGTCATA
CCGGTCGTGGTGCCATCGCTATCCATCCTGACCTTTATCGAAGTAGTACACGGCATCCAGCAGACGCTCGAAGACGCTGG
CTATCAAGTGTTATTGGGTTCGACCGATTTCGACTTGGATCGTGAAACTTCACTGATCGATTCGGTGCTGGGCTACTCGC
CGTCGGGGGTCATTTTGACAGGTCTAAGGCATAACGATAGCACCGTGCAACGCCTCAAGGCCTGGGGCCGGCCAGTGGTC
GAGATCATGGAACTGGGACTGCCTTGCATCGATATGAATGTCGGTGTCGACAACCCTCGAGCGGGGGCCTGTATGGCCCA
GCATCTCCTTGACCGTGGCTATCGCCGCATCGCCTTTCTCGGGGTCGGGATGGCGCGTGACTATCGTGCCCGGCAACGTT
TCGAAGGACATCGCGAGGTGCTGGCTGCCGCAGGGGTCGAGAGTGACCTTCTGTTTACGAGTGAGGAACCATCCTCTTAT
GCAGCAGGACGCCGTGTTTTCCTTGAAGCGCTGGCTGCCCGCCCCGACCTCGATGCGCTTCACTTTGCCAACGACAACCT
CGCAGCCGGCGCGATCCTCGAGGCAAATCGTCAGGGAATCCGCGTGCCTGAAGACATCGCCATTGGCAGCTATCTGGGCC
TGTCTCTCGGCGAACACCTATCGCCTACGCTGACCACCGTGTCGGTGCCACGATTCGAAATGGGAGTCGAGGCGGCGAAG
CTACTGCTAGAGCGGCTAGAAGGTCGGTCGCCTTCTCAACCTCGGATCGATATCGGCTATCGCTTGATCACACGCGAAAG
CACTTGA

Upstream 100 bases:

>100_bases
GGGCAAGCATTCGACTTAGACTTATTGGTAGCGCTACCAGATAATTCCCATCAGAATGGGATAGCAGGAATACAATCTGT
ACAGCACGAGGACACCTTTC

Downstream 100 bases:

>100_bases
GGATCGTCAATAGAGAGATCATGGCATGAAACAACTCTTGGCCGCCTTCTATGGCGATGATTTCACAGGCTCGACGGAAA
ACTTGGCGCAATTCTGCCGC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MANEKPSPRGRRRHHGDNRVTIDDVAKEAGVAPITVSRALNTPDKVSAKLRERVDQAVTSLGYVPNLIAGGLASAGTRVI
PVVVPSLSILTFIEVVHGIQQTLEDAGYQVLLGSTDFDLDRETSLIDSVLGYSPSGVILTGLRHNDSTVQRLKAWGRPVV
EIMELGLPCIDMNVGVDNPRAGACMAQHLLDRGYRRIAFLGVGMARDYRARQRFEGHREVLAAAGVESDLLFTSEEPSSY
AAGRRVFLEALAARPDLDALHFANDNLAAGAILEANRQGIRVPEDIAIGSYLGLSLGEHLSPTLTTVSVPRFEMGVEAAK
LLLERLEGRSPSQPRIDIGYRLITREST

Sequences:

>Translated_348_residues
MANEKPSPRGRRRHHGDNRVTIDDVAKEAGVAPITVSRALNTPDKVSAKLRERVDQAVTSLGYVPNLIAGGLASAGTRVI
PVVVPSLSILTFIEVVHGIQQTLEDAGYQVLLGSTDFDLDRETSLIDSVLGYSPSGVILTGLRHNDSTVQRLKAWGRPVV
EIMELGLPCIDMNVGVDNPRAGACMAQHLLDRGYRRIAFLGVGMARDYRARQRFEGHREVLAAAGVESDLLFTSEEPSSY
AAGRRVFLEALAARPDLDALHFANDNLAAGAILEANRQGIRVPEDIAIGSYLGLSLGEHLSPTLTTVSVPRFEMGVEAAK
LLLERLEGRSPSQPRIDIGYRLITREST
>Mature_347_residues
ANEKPSPRGRRRHHGDNRVTIDDVAKEAGVAPITVSRALNTPDKVSAKLRERVDQAVTSLGYVPNLIAGGLASAGTRVIP
VVVPSLSILTFIEVVHGIQQTLEDAGYQVLLGSTDFDLDRETSLIDSVLGYSPSGVILTGLRHNDSTVQRLKAWGRPVVE
IMELGLPCIDMNVGVDNPRAGACMAQHLLDRGYRRIAFLGVGMARDYRARQRFEGHREVLAAAGVESDLLFTSEEPSSYA
AGRRVFLEALAARPDLDALHFANDNLAAGAILEANRQGIRVPEDIAIGSYLGLSLGEHLSPTLTTVSVPRFEMGVEAAKL
LLERLEGRSPSQPRIDIGYRLITREST

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=325, Percent_Identity=35.6923076923077, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1790715, Length=326, Percent_Identity=31.5950920245399, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1790369, Length=330, Percent_Identity=30.9090909090909, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1787948, Length=332, Percent_Identity=26.5060240963855, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1790194, Length=336, Percent_Identity=26.7857142857143, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789202, Length=299, Percent_Identity=29.4314381270903, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789068, Length=333, Percent_Identity=27.6276276276276, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1787580, Length=335, Percent_Identity=26.865671641791, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1788474, Length=317, Percent_Identity=28.0757097791798, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787906, Length=337, Percent_Identity=26.7062314540059, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786540, Length=321, Percent_Identity=25.5451713395639, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790689, Length=322, Percent_Identity=26.3975155279503, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786268, Length=277, Percent_Identity=25.2707581227437, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37717; Mature: 37585

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANEKPSPRGRRRHHGDNRVTIDDVAKEAGVAPITVSRALNTPDKVSAKLRERVDQAVTS
CCCCCCCCCCHHHCCCCCCEEHHHHHHHCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHHH
LGYVPNLIAGGLASAGTRVIPVVVPSLSILTFIEVVHGIQQTLEDAGYQVLLGSTDFDLD
HCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
RETSLIDSVLGYSPSGVILTGLRHNDSTVQRLKAWGRPVVEIMELGLPCIDMNVGVDNPR
HHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCCCC
AGACMAQHLLDRGYRRIAFLGVGMARDYRARQRFEGHREVLAAAGVESDLLFTSEEPSSY
HHHHHHHHHHHHHHHEEHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHH
AAGRRVFLEALAARPDLDALHFANDNLAAGAILEANRQGIRVPEDIAIGSYLGLSLGEHL
HHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCC
SPTLTTVSVPRFEMGVEAAKLLLERLEGRSPSQPRIDIGYRLITREST
CCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEECEEEEEECCC
>Mature Secondary Structure 
ANEKPSPRGRRRHHGDNRVTIDDVAKEAGVAPITVSRALNTPDKVSAKLRERVDQAVTS
CCCCCCCCCHHHCCCCCCEEHHHHHHHCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHHH
LGYVPNLIAGGLASAGTRVIPVVVPSLSILTFIEVVHGIQQTLEDAGYQVLLGSTDFDLD
HCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
RETSLIDSVLGYSPSGVILTGLRHNDSTVQRLKAWGRPVVEIMELGLPCIDMNVGVDNPR
HHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCCCC
AGACMAQHLLDRGYRRIAFLGVGMARDYRARQRFEGHREVLAAAGVESDLLFTSEEPSSY
HHHHHHHHHHHHHHHEEHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHH
AAGRRVFLEALAARPDLDALHFANDNLAAGAILEANRQGIRVPEDIAIGSYLGLSLGEHL
HHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCC
SPTLTTVSVPRFEMGVEAAKLLLERLEGRSPSQPRIDIGYRLITREST
CCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEECEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]