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The map label for this gene is dtd

Identifier: 92115250

GI number: 92115250

Start: 3491396

End: 3491833

Strand: Direct

Name: dtd

Synonym: Csal_3135

Alternate gene names: 92115250

Gene position: 3491396-3491833 (Clockwise)

Preceding gene: 92115249

Following gene: 92115252

Centisome position: 94.45

GC content: 68.04

Gene sequence:

>438_bases
ATGCGAGCCGTCATCCAACGTGTCCGTCACGCCGGCGTCGATGTCGACGCCCGAACCACCGGCGCCATCGAACAAGGCCT
GATGGTGCTGGTCGGCGTGGCCCCGGACGACACCCAGACCCGCGCCGACAAGATGCTGCACAAGCTGCTCGGGCTGCGGG
TGTTCAGCGACGAGGCGGGCAAGATGAACCTCAACGTGCAACAGGTCGAGGGCGGCCTGTTGCTGGTTCCGCAGTTCACC
CTCATGGCCAACACCACCAAGGGCCTGCGCCCGGGATTCGACGGCGCCGCGCCGCCCGCGCACGGCGAGGCACTGTTCGA
CTATCTGGTGGCGCAGGCCCGGCACGCCTGGCCATACGTCGCCACCGGCGAGTTCGGCGCCGACATGCAGGTCTCGCTGC
TCAACGACGGCCCGGTGACCTTCATCGTCGAGACCTGA

Upstream 100 bases:

>100_bases
CCTGATCGAGCGCTTGCTCGCCGACGTGCATGTGGACATGATGGTGTGCCGCGCCTGGTAGCGCGAATCTTCACCCCTCG
CGTCCACAAGGATCTTGCAC

Downstream 100 bases:

>100_bases
GGCTGCCCGGGGCTGAGTCGCGCCGGGATCAGGCGTCGTCCAGCAGTTCCGCCTCGCGTTGCTCGAGCGCTTCCTCGGCC
TCGAGCCAACGCTGCTCCAG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MRAVIQRVRHAGVDVDARTTGAIEQGLMVLVGVAPDDTQTRADKMLHKLLGLRVFSDEAGKMNLNVQQVEGGLLLVPQFT
LMANTTKGLRPGFDGAAPPAHGEALFDYLVAQARHAWPYVATGEFGADMQVSLLNDGPVTFIVET

Sequences:

>Translated_145_residues
MRAVIQRVRHAGVDVDARTTGAIEQGLMVLVGVAPDDTQTRADKMLHKLLGLRVFSDEAGKMNLNVQQVEGGLLLVPQFT
LMANTTKGLRPGFDGAAPPAHGEALFDYLVAQARHAWPYVATGEFGADMQVSLLNDGPVTFIVET
>Mature_145_residues
MRAVIQRVRHAGVDVDARTTGAIEQGLMVLVGVAPDDTQTRADKMLHKLLGLRVFSDEAGKMNLNVQQVEGGLLLVPQFT
LMANTTKGLRPGFDGAAPPAHGEALFDYLVAQARHAWPYVATGEFGADMQVSLLNDGPVTFIVET

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=148, Percent_Identity=39.8648648648649, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=52.0833333333333, Blast_Score=155, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI115533292, Length=148, Percent_Identity=34.4594594594595, Blast_Score=79, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=39.1891891891892, Blast_Score=111, Evalue=4e-26,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=36.734693877551, Blast_Score=90, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_CHRSD (Q1QSS9)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_575178.1
- ProteinModelPortal:   Q1QSS9
- SMR:   Q1QSS9
- STRING:   Q1QSS9
- GeneID:   4028602
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_3135
- NMPDR:   fig|290398.4.peg.3030
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- BioCyc:   CSAL290398:CSAL_3135-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 15584; Mature: 15584

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVIQRVRHAGVDVDARTTGAIEQGLMVLVGVAPDDTQTRADKMLHKLLGLRVFSDEAG
CHHHHHHHHHCCCCCCCCCCCHHHCCEEEEEEECCCCCHHHHHHHHHHHHCCEEECCCCC
KMNLNVQQVEGGLLLVPQFTLMANTTKGLRPGFDGAAPPAHGEALFDYLVAQARHAWPYV
EECCCCEEECCCEEEECCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
ATGEFGADMQVSLLNDGPVTFIVET
EECCCCCCEEEEEECCCCEEEEEEC
>Mature Secondary Structure
MRAVIQRVRHAGVDVDARTTGAIEQGLMVLVGVAPDDTQTRADKMLHKLLGLRVFSDEAG
CHHHHHHHHHCCCCCCCCCCCHHHCCEEEEEEECCCCCHHHHHHHHHHHHCCEEECCCCC
KMNLNVQQVEGGLLLVPQFTLMANTTKGLRPGFDGAAPPAHGEALFDYLVAQARHAWPYV
EECCCCEEECCCEEEECCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEE
ATGEFGADMQVSLLNDGPVTFIVET
EECCCCCCEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA