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The map label for this gene is xerC

Identifier: 92115230

GI number: 92115230

Start: 3469903

End: 3470799

Strand: Direct

Name: xerC

Synonym: Csal_3115

Alternate gene names: 92115230

Gene position: 3469903-3470799 (Clockwise)

Preceding gene: 92115229

Following gene: 92115231

Centisome position: 93.87

GC content: 71.13

Gene sequence:

>897_bases
ATGCACGCCGCGGTTGAACGCTTCCTGCACAGCCTGTCGGGGCATGCCAGCCCCGCGACGCTGGATGCCTACCGGCGCGA
CCTGACCGCGCTGGCACGCTTTCTCGAGGCGAGCGGCATCGATGACTGGGCGGCACTCGACGTCGCCCAGGTGCGCCGCT
TCATGGGCGCCGAACGCACACGCGGCCTGGCGCCGCGCAGCCTCGCCCGCCGCCGTGCCGCGCTCTCGCGTTTCGCCGAC
CACCTGGTGCGCAGCGGCATCCTCGATCACAACCCGGTGGCGCTGACCCAGACGCCCCGTCAGCCCCGGCATCTGCCACG
CCCGGTGGATGTCGATCAGCTCGCGCGCTTCCTGGATACCCCGCACGACGGGACGCCGCTCGCCGTGCGCGATCAAGCCA
TGCTGGAACTGTTCTATTCATGCGGGTTGCGTCTGGCGGAACTCACGGCACTGGACGTCACCGACCTCGATGCACGCCGC
CTGCGCGTGGTGGGCAAGGGCAACAAGCCTCGCCAGATGCCCATCGGCCGGCGCGCGCAGGCGGCCCTGGCGGACTGGTA
CCGGCTGCGCGGCCAGCTCGCCGGGCATGACGAGCCCGCCCTCTTCGTCGGCCAGCGTGGGGCGCGGCTGGGCCATCGTG
CGGTACAGAAACGCCTCGCTCAGCTCGCCCGCGAGCGAGGGCTGGCCGAGCACCTGCACCCCCATCGCTTGCGCCACTCC
TTCGCCAGTCACTTGCTCGAGTCGAGCCAGGACCTGCGTGCCGTGCAGGAACTGCTGGGGCACGCCAACCTCTCCACCAC
CCAGGTCTATACCCGGCTCGACTGGCAGCATCTGGCCGATGCCTACGATCAGGCGCACCCCCGCGCCCGGCGTCGCGCGC
CACCGGACGACACCTGA

Upstream 100 bases:

>100_bases
AGCCAGGAGAGCGAACACTTCCGCGCCACGCTCGATACGCTATTCACCGATTACCTCGGGGAAATCGTCGGGCGACTCCT
CGTGCGCCTGGATGCTGCGC

Downstream 100 bases:

>100_bases
CACCGCCGCCCCGGAGAATGCCCCATGGCGATCACCGCCCTCACTTTCGATCTCGACGACACCCTCTGGGACAACCGCCC
CATTCTCGAACGCGCCGAGG

Product: phage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MHAAVERFLHSLSGHASPATLDAYRRDLTALARFLEASGIDDWAALDVAQVRRFMGAERTRGLAPRSLARRRAALSRFAD
HLVRSGILDHNPVALTQTPRQPRHLPRPVDVDQLARFLDTPHDGTPLAVRDQAMLELFYSCGLRLAELTALDVTDLDARR
LRVVGKGNKPRQMPIGRRAQAALADWYRLRGQLAGHDEPALFVGQRGARLGHRAVQKRLAQLARERGLAEHLHPHRLRHS
FASHLLESSQDLRAVQELLGHANLSTTQVYTRLDWQHLADAYDQAHPRARRRAPPDDT

Sequences:

>Translated_298_residues
MHAAVERFLHSLSGHASPATLDAYRRDLTALARFLEASGIDDWAALDVAQVRRFMGAERTRGLAPRSLARRRAALSRFAD
HLVRSGILDHNPVALTQTPRQPRHLPRPVDVDQLARFLDTPHDGTPLAVRDQAMLELFYSCGLRLAELTALDVTDLDARR
LRVVGKGNKPRQMPIGRRAQAALADWYRLRGQLAGHDEPALFVGQRGARLGHRAVQKRLAQLARERGLAEHLHPHRLRHS
FASHLLESSQDLRAVQELLGHANLSTTQVYTRLDWQHLADAYDQAHPRARRRAPPDDT
>Mature_298_residues
MHAAVERFLHSLSGHASPATLDAYRRDLTALARFLEASGIDDWAALDVAQVRRFMGAERTRGLAPRSLARRRAALSRFAD
HLVRSGILDHNPVALTQTPRQPRHLPRPVDVDQLARFLDTPHDGTPLAVRDQAMLELFYSCGLRLAELTALDVTDLDARR
LRVVGKGNKPRQMPIGRRAQAALADWYRLRGQLAGHDEPALFVGQRGARLGHRAVQKRLAQLARERGLAEHLHPHRLRHS
FASHLLESSQDLRAVQELLGHANLSTTQVYTRLDWQHLADAYDQAHPRARRRAPPDDT

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=50.8474576271186, Blast_Score=277, Evalue=6e-76,
Organism=Escherichia coli, GI1789261, Length=298, Percent_Identity=37.9194630872483, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1790768, Length=146, Percent_Identity=31.5068493150685, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790767, Length=169, Percent_Identity=26.6272189349112, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_CHRSD (Q1QSU9)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_575158.1
- ProteinModelPortal:   Q1QSU9
- SMR:   Q1QSU9
- STRING:   Q1QSU9
- GeneID:   4028756
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_3115
- NMPDR:   fig|290398.4.peg.2817
- eggNOG:   COG4973
- HOGENOM:   HBG727654
- OMA:   RASPHTR
- BioCyc:   CSAL290398:CSAL_3115-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 33524; Mature: 33524

Theoretical pI: Translated: 11.37; Mature: 11.37

Prosite motif: NA

Important sites: ACT_SITE 144-144 ACT_SITE 166-166 ACT_SITE 235-235 ACT_SITE 238-238 ACT_SITE 261-261 ACT_SITE 270-270

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAAVERFLHSLSGHASPATLDAYRRDLTALARFLEASGIDDWAALDVAQVRRFMGAERT
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RGLAPRSLARRRAALSRFADHLVRSGILDHNPVALTQTPRQPRHLPRPVDVDQLARFLDT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHCC
PHDGTPLAVRDQAMLELFYSCGLRLAELTALDVTDLDARRLRVVGKGNKPRQMPIGRRAQ
CCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHEECCCCCCCCCCCCHHHH
AALADWYRLRGQLAGHDEPALFVGQRGARLGHRAVQKRLAQLARERGLAEHLHPHRLRHS
HHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHH
FASHLLESSQDLRAVQELLGHANLSTTQVYTRLDWQHLADAYDQAHPRARRRAPPDDT
HHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCC
>Mature Secondary Structure
MHAAVERFLHSLSGHASPATLDAYRRDLTALARFLEASGIDDWAALDVAQVRRFMGAERT
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RGLAPRSLARRRAALSRFADHLVRSGILDHNPVALTQTPRQPRHLPRPVDVDQLARFLDT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHCC
PHDGTPLAVRDQAMLELFYSCGLRLAELTALDVTDLDARRLRVVGKGNKPRQMPIGRRAQ
CCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHEECCCCCCCCCCCCHHHH
AALADWYRLRGQLAGHDEPALFVGQRGARLGHRAVQKRLAQLARERGLAEHLHPHRLRHS
HHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHH
FASHLLESSQDLRAVQELLGHANLSTTQVYTRLDWQHLADAYDQAHPRARRRAPPDDT
HHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA