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The map label for this gene is uxuA

Identifier: 92115096

GI number: 92115096

Start: 3318704

End: 3319879

Strand: Direct

Name: uxuA

Synonym: Csal_2980

Alternate gene names: 92115096

Gene position: 3318704-3319879 (Clockwise)

Preceding gene: 92115095

Following gene: 92115097

Centisome position: 89.78

GC content: 67.6

Gene sequence:

>1176_bases
ATGGAACACACCTGGCGCTGGTTCGGGCCCGACGACCCGATCACCCTCGACGAGATTCGCCAGACCGGAGCCACCGGTAT
CGTCACCGCCCTGCACGAGATCCCCAACGGCGAAATCTGGCCGGAAGCGGCGATCGCCGAACGCAAGCGCCTGATCGAGG
CCTCGGGTCTTGCCTGGTCGGTCGTCGAAAGCGTCCCCGTGCATGAAGACATCAAGCAGGGGCGCGGCGACTGCGAGACA
CATATCGCCCGCTACCAGCAAACGCTGCGCAACCTGGCGGCCTGCGGCATCGACGTGGTCTGCTACAACTTCATGCCGGT
GCTCGACTGGACGCGCACCGATCTGGCCTGGCCACTGCCCGGCGGGGGCACGGCGCTGCGTTTCGATCAGACCGCCTTCG
CCGCCTTCGACCTTTATCTGCTCGAGCGTCCAGGCGCCGAGGCCGACTACGACGCCACCGAGCGCGACGCCGCACGCGCC
TATCTCGACGGCCTCGACGAGAGTGCCCGCCAGAGGTTGATCGATACCATCATCGCCGGACTGCCCGGCGCCGAGGAGCA
CTACAGCCTGGCACGTTTCCGCGAGGTCATCGCCGAGTATGCCGAGATCGATGCCGAGCGCTTGCGCGACAACCTCGGCC
ACTTCCTGCGTGCGGTGGTGCCGGTGGCCGAGGAGGTCGGCATCCGCCTGGCGATCCATCCCGACGATCCCCCTCGGCCG
CTGCTGGGTCTGCCACGGGTGGTCTCGACCCCCCGTGACGTGCAATGGATTCTCGATGCCGCCCCTAGCCCGGCCAACGG
CCTGACCTTCTGCACCGGCTCCTACGGTGTCAGCGCGGCAATCGACCTGGTGGCGATGGGCGAGCGTTTTGCCGAGCGCA
TCTACTTCGCCCACCTGCGCGCCACGCAGCGCGAGAACGACCCCCGGAGCTTCCACGAATCGGCCCATCTCGACGGCGAC
GTGGACATGGTCGGCGTGATCAAGGCCCTGGTCGGCGAGGAACGCCGCCGCGAACGCGACGGCGGCCCGCGACTGCCCCT
GCGTCCCGATCACGGTCATCACCTGCTCGACGACCTGAGTCGCGACACCCGCCCCGGTTACCCCCTGATCGGTCGGCTCA
AGGGGCTGGCAGAATTGCGTGGGGTCGAGACCGCGATCAAACAACTCGCGATCTAG

Upstream 100 bases:

>100_bases
CTTTTCAGCCGCAGTGCTCGAGGCCTACCGCACACTGGACGAAGGTGGCGTCGAGAGATCGCTGACCGGCCTCGACGCAC
GCACACGATAGGAGACGACC

Downstream 100 bases:

>100_bases
CGCTCCCAGGAGGGGGACGGGTCATACGCAGCTAGCTGACAGAATGGTAGTATCATCGCTGGAGCCTCCCAGGGATGAGC
CACCATGTCACAGTTGAGTC

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MEHTWRWFGPDDPITLDEIRQTGATGIVTALHEIPNGEIWPEAAIAERKRLIEASGLAWSVVESVPVHEDIKQGRGDCET
HIARYQQTLRNLAACGIDVVCYNFMPVLDWTRTDLAWPLPGGGTALRFDQTAFAAFDLYLLERPGAEADYDATERDAARA
YLDGLDESARQRLIDTIIAGLPGAEEHYSLARFREVIAEYAEIDAERLRDNLGHFLRAVVPVAEEVGIRLAIHPDDPPRP
LLGLPRVVSTPRDVQWILDAAPSPANGLTFCTGSYGVSAAIDLVAMGERFAERIYFAHLRATQRENDPRSFHESAHLDGD
VDMVGVIKALVGEERRRERDGGPRLPLRPDHGHHLLDDLSRDTRPGYPLIGRLKGLAELRGVETAIKQLAI

Sequences:

>Translated_391_residues
MEHTWRWFGPDDPITLDEIRQTGATGIVTALHEIPNGEIWPEAAIAERKRLIEASGLAWSVVESVPVHEDIKQGRGDCET
HIARYQQTLRNLAACGIDVVCYNFMPVLDWTRTDLAWPLPGGGTALRFDQTAFAAFDLYLLERPGAEADYDATERDAARA
YLDGLDESARQRLIDTIIAGLPGAEEHYSLARFREVIAEYAEIDAERLRDNLGHFLRAVVPVAEEVGIRLAIHPDDPPRP
LLGLPRVVSTPRDVQWILDAAPSPANGLTFCTGSYGVSAAIDLVAMGERFAERIYFAHLRATQRENDPRSFHESAHLDGD
VDMVGVIKALVGEERRRERDGGPRLPLRPDHGHHLLDDLSRDTRPGYPLIGRLKGLAELRGVETAIKQLAI
>Mature_391_residues
MEHTWRWFGPDDPITLDEIRQTGATGIVTALHEIPNGEIWPEAAIAERKRLIEASGLAWSVVESVPVHEDIKQGRGDCET
HIARYQQTLRNLAACGIDVVCYNFMPVLDWTRTDLAWPLPGGGTALRFDQTAFAAFDLYLLERPGAEADYDATERDAARA
YLDGLDESARQRLIDTIIAGLPGAEEHYSLARFREVIAEYAEIDAERLRDNLGHFLRAVVPVAEEVGIRLAIHPDDPPRP
LLGLPRVVSTPRDVQWILDAAPSPANGLTFCTGSYGVSAAIDLVAMGERFAERIYFAHLRATQRENDPRSFHESAHLDGD
VDMVGVIKALVGEERRRERDGGPRLPLRPDHGHHLLDDLSRDTRPGYPLIGRLKGLAELRGVETAIKQLAI

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family

Homologues:

Organism=Escherichia coli, GI1790778, Length=389, Percent_Identity=61.1825192802057, Blast_Score=506, Evalue=1e-145,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UXUA_CHRSD (Q1QT83)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_575024.1
- ProteinModelPortal:   Q1QT83
- SMR:   Q1QT83
- STRING:   Q1QT83
- GeneID:   4027518
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_2980
- NMPDR:   fig|290398.4.peg.1810
- eggNOG:   COG1312
- HOGENOM:   HBG585927
- OMA:   VHEEIKT
- ProtClustDB:   PRK03906
- BioCyc:   CSAL290398:CSAL_2980-MONOMER
- HAMAP:   MF_00106
- InterPro:   IPR004628
- InterPro:   IPR013022
- Gene3D:   G3DSA:3.20.20.150
- PIRSF:   PIRSF016049
- TIGRFAMs:   TIGR00695

Pfam domain/function: PF03786 UxuA; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =4.2.1.8

Molecular weight: Translated: 43446; Mature: 43446

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHTWRWFGPDDPITLDEIRQTGATGIVTALHEIPNGEIWPEAAIAERKRLIEASGLAWS
CCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHH
VVESVPVHEDIKQGRGDCETHIARYQQTLRNLAACGIDVVCYNFMPVLDWTRTDLAWPLP
HHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCC
GGGTALRFDQTAFAAFDLYLLERPGAEADYDATERDAARAYLDGLDESARQRLIDTIIAG
CCCCEEEECCHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHC
LPGAEEHYSLARFREVIAEYAEIDAERLRDNLGHFLRAVVPVAEEVGIRLAIHPDDPPRP
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCC
LLGLPRVVSTPRDVQWILDAAPSPANGLTFCTGSYGVSAAIDLVAMGERFAERIYFAHLR
CCCCCHHHCCCCHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
ATQRENDPRSFHESAHLDGDVDMVGVIKALVGEERRRERDGGPRLPLRPDHGHHLLDDLS
HHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
RDTRPGYPLIGRLKGLAELRGVETAIKQLAI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEHTWRWFGPDDPITLDEIRQTGATGIVTALHEIPNGEIWPEAAIAERKRLIEASGLAWS
CCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHH
VVESVPVHEDIKQGRGDCETHIARYQQTLRNLAACGIDVVCYNFMPVLDWTRTDLAWPLP
HHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCC
GGGTALRFDQTAFAAFDLYLLERPGAEADYDATERDAARAYLDGLDESARQRLIDTIIAG
CCCCEEEECCHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHC
LPGAEEHYSLARFREVIAEYAEIDAERLRDNLGHFLRAVVPVAEEVGIRLAIHPDDPPRP
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCC
LLGLPRVVSTPRDVQWILDAAPSPANGLTFCTGSYGVSAAIDLVAMGERFAERIYFAHLR
CCCCCHHHCCCCHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
ATQRENDPRSFHESAHLDGDVDMVGVIKALVGEERRRERDGGPRLPLRPDHGHHLLDDLS
HHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
RDTRPGYPLIGRLKGLAELRGVETAIKQLAI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA