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The map label for this gene is coaD

Identifier: 92115051

GI number: 92115051

Start: 3273926

End: 3274429

Strand: Direct

Name: coaD

Synonym: Csal_2935

Alternate gene names: 92115051

Gene position: 3273926-3274429 (Clockwise)

Preceding gene: 92115050

Following gene: 92115052

Centisome position: 88.56

GC content: 60.91

Gene sequence:

>504_bases
ATGAATATCGTGGTCTATCCCGGTACCTTCGACCCCGTGACCAATGGCCATTACGACCTGATCGAGCGCGCCTCACGCAT
GTTCGACAAGGTCGTGGTGGCGGTGGCGGCGAGTCCGCGCAAGCAACCCACGCTATCCCTGGAGACCCGGGTGGCGCTGA
TCGAGGAAGTCACCGCCGACCTCGACAACGTCACCGTGACCGGCTTCAGCTGCCTGCTGACGCAACTGCTGGCGCAACAG
AACGCGCGCATCATCCTGCGCGGTCTGAGAGCGGTATCCGACTTCGAATATGAGTTACAATTGGCCAATATGAACCGGGC
CCAGGCACCTGACGTGGAAAGCCTGTTCCTGACGCCCGAGGTCGAGAACTCGTATATTTCTTCCACTATCGTGCGCGAGA
TCGCGCGTCTGGGGGGAGATGTCTCCAAGCTCGTGCATCCCTGCGTGGTCGATGCGCTGAGCCGGCATTTCGCCCAGGAC
CCCTCGTCGCCCAAGACGCAATAG

Upstream 100 bases:

>100_bases
CAACCCCTACGGTCAGCTGTGAAGGCGGCTCCGGGCGTCGACATTGTCGCCGCCCGGCGCCAACCACTACCCTGATGGTG
TCTCGGCACAGGATGCATCC

Downstream 100 bases:

>100_bases
AGGACGGACGCTTTATGGCTTTGATGATCACCGACGAGTGCATCAACTGCGACGTCTGCGAACCCGAGTGCCCCAACGGC
GCCATTTCCCCGGGTGAGGA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MNIVVYPGTFDPVTNGHYDLIERASRMFDKVVVAVAASPRKQPTLSLETRVALIEEVTADLDNVTVTGFSCLLTQLLAQQ
NARIILRGLRAVSDFEYELQLANMNRAQAPDVESLFLTPEVENSYISSTIVREIARLGGDVSKLVHPCVVDALSRHFAQD
PSSPKTQ

Sequences:

>Translated_167_residues
MNIVVYPGTFDPVTNGHYDLIERASRMFDKVVVAVAASPRKQPTLSLETRVALIEEVTADLDNVTVTGFSCLLTQLLAQQ
NARIILRGLRAVSDFEYELQLANMNRAQAPDVESLFLTPEVENSYISSTIVREIARLGGDVSKLVHPCVVDALSRHFAQD
PSSPKTQ
>Mature_167_residues
MNIVVYPGTFDPVTNGHYDLIERASRMFDKVVVAVAASPRKQPTLSLETRVALIEEVTADLDNVTVTGFSCLLTQLLAQQ
NARIILRGLRAVSDFEYELQLANMNRAQAPDVESLFLTPEVENSYISSTIVREIARLGGDVSKLVHPCVVDALSRHFAQD
PSSPKTQ

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=149, Percent_Identity=54.3624161073826, Blast_Score=178, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_CHRSD (Q1QTC8)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_574979.1
- ProteinModelPortal:   Q1QTC8
- SMR:   Q1QTC8
- STRING:   Q1QTC8
- GeneID:   4028330
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_2935
- NMPDR:   fig|290398.4.peg.3133
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- BioCyc:   CSAL290398:CSAL_2935-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18414; Mature: 18414

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVVYPGTFDPVTNGHYDLIERASRMFDKVVVAVAASPRKQPTLSLETRVALIEEVTAD
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHC
LDNVTVTGFSCLLTQLLAQQNARIILRGLRAVSDFEYELQLANMNRAQAPDVESLFLTPE
CCCEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCCCEEECCC
VENSYISSTIVREIARLGGDVSKLVHPCVVDALSRHFAQDPSSPKTQ
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNIVVYPGTFDPVTNGHYDLIERASRMFDKVVVAVAASPRKQPTLSLETRVALIEEVTAD
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHC
LDNVTVTGFSCLLTQLLAQQNARIILRGLRAVSDFEYELQLANMNRAQAPDVESLFLTPE
CCCEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHEEEECCCCCCCCCCCCCEEECCC
VENSYISSTIVREIARLGGDVSKLVHPCVVDALSRHFAQDPSSPKTQ
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA