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The map label for this gene is holC [H]

Identifier: 92115037

GI number: 92115037

Start: 3254185

End: 3254637

Strand: Direct

Name: holC [H]

Synonym: Csal_2921

Alternate gene names: 92115037

Gene position: 3254185-3254637 (Clockwise)

Preceding gene: 92115036

Following gene: 92115038

Centisome position: 88.03

GC content: 66.45

Gene sequence:

>453_bases
ATGACTCAAGTCGATTTCTACATCTTGCCCGATACCACGCTGGACGCGCGGCTGGCCTTCGCCTGCCGCCTGGCGGAGAC
CATTCATCGCAAGGGCTATCGGCTGCATATCCACACCGAGGACGAGACCATGGCGCGCGAGCTCGACGAGCGGCTGTGGA
CCTTCAAGCCCGAGAGCTACCTGCCCCACGCGGTGCTGGGCGACGATGTCTCGCCCGAGCCGCCCGTGACCCTCGGCTGG
GAAGCGCCGCCCGCGCCCGGTGTGGAGGCGATGCTCAACCTGCATCCCGAGATCCCCGAGTGGTTCTCGCGCTTCGAGCG
CGTCGCCGAGATCATCAACCAGCATCAGGACGTGCTGACCGCCAAGCGCGCCTGCTGGCAGACCTATAAAAAGCGCGGCT
ACCCCGTCAAGGCCAACGACCTCACCGGCTCGTCGCGCCACGCGACGGGCTGA

Upstream 100 bases:

>100_bases
TGGGGCGCATCGGCGAGCCCGAGGAAATCGCCAACGGCGTGCTGTGGCTGGCCGAGGCCGGCTTCACCACCGGGGCGTTG
ATCGATATCGACGGCGGCGT

Downstream 100 bases:

>100_bases
GCGCGCCATGACGCCACCCCGCTTGCGGGGTTATACTTGCCGGCATTTTTCGCCACGGCCGCGGGCCGTGTTGACGTCAT
TTCGAGAGCCGACCGACGCC

Product: DNA polymerase III chi subunit, HolC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MTQVDFYILPDTTLDARLAFACRLAETIHRKGYRLHIHTEDETMARELDERLWTFKPESYLPHAVLGDDVSPEPPVTLGW
EAPPAPGVEAMLNLHPEIPEWFSRFERVAEIINQHQDVLTAKRACWQTYKKRGYPVKANDLTGSSRHATG

Sequences:

>Translated_150_residues
MTQVDFYILPDTTLDARLAFACRLAETIHRKGYRLHIHTEDETMARELDERLWTFKPESYLPHAVLGDDVSPEPPVTLGW
EAPPAPGVEAMLNLHPEIPEWFSRFERVAEIINQHQDVLTAKRACWQTYKKRGYPVKANDLTGSSRHATG
>Mature_149_residues
TQVDFYILPDTTLDARLAFACRLAETIHRKGYRLHIHTEDETMARELDERLWTFKPESYLPHAVLGDDVSPEPPVTLGWE
APPAPGVEAMLNLHPEIPEWFSRFERVAEIINQHQDVLTAKRACWQTYKKRGYPVKANDLTGSSRHATG

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2927

COG function: function code L; DNA polymerase III, chi subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007459 [H]

Pfam domain/function: PF04364 DNA_pol3_chi [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 17196; Mature: 17064

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQVDFYILPDTTLDARLAFACRLAETIHRKGYRLHIHTEDETMARELDERLWTFKPESY
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCCC
LPHAVLGDDVSPEPPVTLGWEAPPAPGVEAMLNLHPEIPEWFSRFERVAEIINQHQDVLT
CCCHHCCCCCCCCCCEEECCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AKRACWQTYKKRGYPVKANDLTGSSRHATG
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TQVDFYILPDTTLDARLAFACRLAETIHRKGYRLHIHTEDETMARELDERLWTFKPESY
CCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCCC
LPHAVLGDDVSPEPPVTLGWEAPPAPGVEAMLNLHPEIPEWFSRFERVAEIINQHQDVLT
CCCHHCCCCCCCCCCEEECCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AKRACWQTYKKRGYPVKANDLTGSSRHATG
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9864319; 10984043 [H]