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The map label for this gene is trkH [H]

Identifier: 92114990

GI number: 92114990

Start: 3204087

End: 3205535

Strand: Direct

Name: trkH [H]

Synonym: Csal_2873

Alternate gene names: 92114990

Gene position: 3204087-3205535 (Clockwise)

Preceding gene: 92114989

Following gene: 92114991

Centisome position: 86.68

GC content: 63.84

Gene sequence:

>1449_bases
ATGAGTCTTCTGGTGATCCTGCGGATCGTCGGGCTGCTGTTGATGCTGTTCAGCCTGACCATGGTACCGCCGGTGGCGAT
ATCGTTGATCTTCGACGATGCCACCTGGGACGCCTTCGTCATTGGCCTGGGGATCTCGTTCGCCACGGGGATGGCGCTGT
ACTGGCCCACCCGCCACGCGCGACGCGAGCTGCGTACCCGTGACGGTTTCTTGATCACCGTGATGTTCTGGAGCGTGCTG
GGGCTGTTCGGCTCGCTGCCCCTGATGCTCGCCGAGGATCCCTCGCTGTCGCTCACCGACGCGGTGTTCGAGTCCTTCTC
GGGCCTCACCACCACCGGGGCGACGGTTCTCACCGGCATCGACCTGCTGCCCGAATCGATTCGCTTCTACCGCCAGCAGC
TGCAGTGGCTGGGTGGCATGGGGATCGTGGTCCTGGCGGTGGCGATCCTGCCGACGCTGGGCATCGGTGGCATGCAGCTC
TACCGCACCGAGATCCCGGGGCCGCTCAAGGACTCCAAGCTGACACCGCGCATCACCGAGACCGCCAAGGCACTGTGGTA
TATCTACGCCGCCCTGACGCTGGCGTGTTTTCTGGCTTACTGGCTCGCAGGCATGAGCTGGTTCGACGCCATCGGGCATA
GCTTTTCCACCGTCGCCATCGGCGGCTTCTCGACCCACGATGCCAGCATCGGCTATTTCGACAGCGCCACCATCGAACTC
ATCTGCGTGTTCTTCATGGTGATCTCGTCGCTGAGCTTCGGGCTGCACTTCGCGGTGTGGCGTGAGAAACGCCTGCGCCA
TTATCTGGTCGATCCGGAATTCCGCTTCTTCATCATCTTTCTAACGTTGCTGGTCACCATCACCATCGCCACGCTCATGC
TCAGCGGCACCTACACCGACACCCTGGGGCTGCGCCACGGCCTGTTCGAAGTGGTCTCGGTGGCCACCACCACCGGATTC
GGGGTCGCCGACTTCACCGCCTGGCCGGGCGTGCTGCCGTTCATGCTGTTCATCGCCGCCTTCGTCGGGGCCTGCTCGGG
TTCCGCCGGCGGGGGCATGAAGGTGATCCGCATCCTGCTGATCCTCAAGCAGGGGCTGCGCGAGATTCATCGCCTGATCC
ACCCCAACGCGGTGTTCTCGGTCAAGGTGGGCAAGATGCGCATTTCCAGCGGCGTGGCCGAGGCGGTATGGGGCTTTTTC
TCCGCCTATCTGCTGCTCTTCGTGCTGATGCTGATGGTCCTGCTGGCCACCGGGCTGGACCAGGTCACGGCCTGGTCGGC
GGTGGGCTCGGCGCTCAACAACCTGGGGCCGGGGTTGGGCAGCGTGGCCACGCACTACGGCGACATGCCGGCGCTCGCCA
AGTGGACCCTGGTAATGGCCATGATGTTCGGCCGTCTGGAAATCTTCACCATCCTGGTGCTGTTCACACCGGCCTTCTGG
CGCCGCTGA

Upstream 100 bases:

>100_bases
CGACGCATTCGCGATGTCGAGCGGCTCTTCCAGGTAGGGCTGACTTTCTTCTGATGAGTACGACGTCCCCCGCGCACCCG
GCGCCGACACGGCGGACGCC

Downstream 100 bases:

>100_bases
CCGAGCGCTGCCGCGCGACAACATTCACTGTTGAATCGCACGCCAGCTGAAGATTTCTCCCTCAATCCTGCCGAAACGGC
ACGCTTCTTACCAAAGGATG

Product: K+ transporter Trk

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MSLLVILRIVGLLLMLFSLTMVPPVAISLIFDDATWDAFVIGLGISFATGMALYWPTRHARRELRTRDGFLITVMFWSVL
GLFGSLPLMLAEDPSLSLTDAVFESFSGLTTTGATVLTGIDLLPESIRFYRQQLQWLGGMGIVVLAVAILPTLGIGGMQL
YRTEIPGPLKDSKLTPRITETAKALWYIYAALTLACFLAYWLAGMSWFDAIGHSFSTVAIGGFSTHDASIGYFDSATIEL
ICVFFMVISSLSFGLHFAVWREKRLRHYLVDPEFRFFIIFLTLLVTITIATLMLSGTYTDTLGLRHGLFEVVSVATTTGF
GVADFTAWPGVLPFMLFIAAFVGACSGSAGGGMKVIRILLILKQGLREIHRLIHPNAVFSVKVGKMRISSGVAEAVWGFF
SAYLLLFVLMLMVLLATGLDQVTAWSAVGSALNNLGPGLGSVATHYGDMPALAKWTLVMAMMFGRLEIFTILVLFTPAFW
RR

Sequences:

>Translated_482_residues
MSLLVILRIVGLLLMLFSLTMVPPVAISLIFDDATWDAFVIGLGISFATGMALYWPTRHARRELRTRDGFLITVMFWSVL
GLFGSLPLMLAEDPSLSLTDAVFESFSGLTTTGATVLTGIDLLPESIRFYRQQLQWLGGMGIVVLAVAILPTLGIGGMQL
YRTEIPGPLKDSKLTPRITETAKALWYIYAALTLACFLAYWLAGMSWFDAIGHSFSTVAIGGFSTHDASIGYFDSATIEL
ICVFFMVISSLSFGLHFAVWREKRLRHYLVDPEFRFFIIFLTLLVTITIATLMLSGTYTDTLGLRHGLFEVVSVATTTGF
GVADFTAWPGVLPFMLFIAAFVGACSGSAGGGMKVIRILLILKQGLREIHRLIHPNAVFSVKVGKMRISSGVAEAVWGFF
SAYLLLFVLMLMVLLATGLDQVTAWSAVGSALNNLGPGLGSVATHYGDMPALAKWTLVMAMMFGRLEIFTILVLFTPAFW
RR
>Mature_481_residues
SLLVILRIVGLLLMLFSLTMVPPVAISLIFDDATWDAFVIGLGISFATGMALYWPTRHARRELRTRDGFLITVMFWSVLG
LFGSLPLMLAEDPSLSLTDAVFESFSGLTTTGATVLTGIDLLPESIRFYRQQLQWLGGMGIVVLAVAILPTLGIGGMQLY
RTEIPGPLKDSKLTPRITETAKALWYIYAALTLACFLAYWLAGMSWFDAIGHSFSTVAIGGFSTHDASIGYFDSATIELI
CVFFMVISSLSFGLHFAVWREKRLRHYLVDPEFRFFIIFLTLLVTITIATLMLSGTYTDTLGLRHGLFEVVSVATTTGFG
VADFTAWPGVLPFMLFIAAFVGACSGSAGGGMKVIRILLILKQGLREIHRLIHPNAVFSVKVGKMRISSGVAEAVWGFFS
AYLLLFVLMLMVLLATGLDQVTAWSAVGSALNNLGPGLGSVATHYGDMPALAKWTLVMAMMFGRLEIFTILVLFTPAFWR
R

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=483, Percent_Identity=56.1076604554865, Blast_Score=508, Evalue=1e-145,
Organism=Escherichia coli, GI1787626, Length=477, Percent_Identity=40.041928721174, Blast_Score=373, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52819; Mature: 52687

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00778 HIS_ACID_PHOSPHAT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLVILRIVGLLLMLFSLTMVPPVAISLIFDDATWDAFVIGLGISFATGMALYWPTRHA
CHHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCHHHHHHHHHHHHHCCCCEECCCHHH
RRELRTRDGFLITVMFWSVLGLFGSLPLMLAEDPSLSLTDAVFESFSGLTTTGATVLTGI
HHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHH
DLLPESIRFYRQQLQWLGGMGIVVLAVAILPTLGIGGMQLYRTEIPGPLKDSKLTPRITE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCHHHH
TAKALWYIYAALTLACFLAYWLAGMSWFDAIGHSFSTVAIGGFSTHDASIGYFDSATIEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHH
ICVFFMVISSLSFGLHFAVWREKRLRHYLVDPEFRFFIIFLTLLVTITIATLMLSGTYTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
TLGLRHGLFEVVSVATTTGFGVADFTAWPGVLPFMLFIAAFVGACSGSAGGGMKVIRILL
HHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ILKQGLREIHRLIHPNAVFSVKVGKMRISSGVAEAVWGFFSAYLLLFVLMLMVLLATGLD
HHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
QVTAWSAVGSALNNLGPGLGSVATHYGDMPALAKWTLVMAMMFGRLEIFTILVLFTPAFW
HHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RR
CC
>Mature Secondary Structure 
SLLVILRIVGLLLMLFSLTMVPPVAISLIFDDATWDAFVIGLGISFATGMALYWPTRHA
HHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCHHHHHHHHHHHHHCCCCEECCCHHH
RRELRTRDGFLITVMFWSVLGLFGSLPLMLAEDPSLSLTDAVFESFSGLTTTGATVLTGI
HHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHH
DLLPESIRFYRQQLQWLGGMGIVVLAVAILPTLGIGGMQLYRTEIPGPLKDSKLTPRITE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCHHHH
TAKALWYIYAALTLACFLAYWLAGMSWFDAIGHSFSTVAIGGFSTHDASIGYFDSATIEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHH
ICVFFMVISSLSFGLHFAVWREKRLRHYLVDPEFRFFIIFLTLLVTITIATLMLSGTYTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
TLGLRHGLFEVVSVATTTGFGVADFTAWPGVLPFMLFIAAFVGACSGSAGGGMKVIRILL
HHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ILKQGLREIHRLIHPNAVFSVKVGKMRISSGVAEAVWGFFSAYLLLFVLMLMVLLATGLD
HHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
QVTAWSAVGSALNNLGPGLGSVATHYGDMPALAKWTLVMAMMFGRLEIFTILVLFTPAFW
HHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]