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Identifier: 92114975

GI number: 92114975

Start: 3189053

End: 3190456

Strand: Direct

Name: der

Synonym: Csal_2858

Alternate gene names: 92114975

Gene position: 3189053-3190456 (Clockwise)

Preceding gene: 92114974

Following gene: 92114978

Centisome position: 86.27

GC content: 65.24

Gene sequence:

>1404_bases
ATGAATCCCGTCATCGCCCTGGTAGGCCGACCCAATGTCGGCAAGTCGACCCTCTTCAATCGTCTGACCCGCACGCGCGA
CGCGCTGGTCGCCGACTTCCCCGGCCTGACGCGTGACCGCAAGTACGGCAACGGCGTTCTCGGCGACAAGACCTACACCG
TCATCGATACCGGCGGCATCAGCGGCAACGAGGAAGGCCTCGACGCCGCCATGGCCGAGCAGTCGCTGCTGGCCATCGAC
GAAGCCGACATCGTGCTGTTCATGGTCGACGGACGCACCGGGCTCAATGTCGCCGACGAGGCCATCGCCAACCACCTGCG
CGTCAATCAGAAGAAGACCTGGCTGGTGGTCAACAAGACGGACGGTCTGGAAGAGCACTCGGCAATGGCCGAGTTCTGGC
GGCTCGGCCTGGGCGACCCGCGTCCCATCGCCGCCGCGCACGGGCGCAACGTCACCAGCTTGATCGACGAGGTCCTGGCG
CCCTTCCCGCCGCGTGAAGCCAACGCCGCACCGCCGGATCTCAGCAATGGCATCCGCATCGGCGTCATCGGACGGCCCAA
CGTGGGCAAGTCGACGCTGGTCAATCGCCTGCTGGGCGAAGACCGGGTGGTGGTATACGACGAAGCCGGTACCACCCGCG
ACGCCATCGAGATTCCCTTCGAGCGCCGGGGCAAGCCCTACGTGCTGGTCGATACCGCCGGCGTGCGGCGACGCAAGAAC
GTCAGCGAGGCGGCCGAGAAATTCTCGATCATCAAGACGCTCGAGGCCATCAAGGCCTGCAACGTGGCCATCATGGTGCT
CGACGCCCGTAGCGGCCTGGTCGAACAGGACCTGCACCTGCTCGATTACGTGCTGAGCAGCGGCCGCGCTCTGGTTCTGG
CGGTCAACAAGTGGGATGGACTCGAACAGGAAGCCAAGGACAAGATGCGCGCCGCGATCAAGCGACGCCTGGGCTTCGCC
GATTATGCCGAGATGCATTTCATCTCGGCGCTGCACGGTACCGCGGTGGGCGATCTCTACCCGTCCATCACCCGTGCCTT
CGATTCGGCCAACAGCCACTGGTCGACCAACCGCCTGACCACCATCCTGCAGGACGCGGTGAGCGAGCATCAGCCACCCT
TGATCCACGGCCGCCGCATCAAGTTGCGCATGGCCCACCAGGGCGGCAGCAACCCGCCGATCATCGTGGTCCACGGCAAT
CAGACCGGCTCGCTCCCCGAGGCCTACAAGCGCTACCTGACCAATACCTTCCGCAAGGTTCTCAAGGTGCGCGGCACGCC
GCTGCGCTTCGAGTTTCGCTCGGGCAAGAACCCCTACGACAGCAACCCCGACGCGAGCGATCGCGAGAAGGCCAAGCAAC
GCGAACTGGGGCGCACGCGCGAGGCACGCAAGAACCGTCGCTGA

Upstream 100 bases:

>100_bases
TCACCCCCAGCGACAGCGTGGCGCTCGCGTCACGCACTTGGCGCGCGGTATCGCGCGACAGCCTCACTCACCGCTTCCGT
TCGCCGGTTTACGAGACAAC

Downstream 100 bases:

>100_bases
CGCCGATCAGCCCTCGGCGAGGACGCAATTGCGTCCCGCCAGCTTGGCGCGATACAGCCGACGCCCCACCACATCGAGCC
CCAATTCGACGCTTTCCGCC

Product: small GTP-binding protein

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MNPVIALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGNGVLGDKTYTVIDTGGISGNEEGLDAAMAEQSLLAID
EADIVLFMVDGRTGLNVADEAIANHLRVNQKKTWLVVNKTDGLEEHSAMAEFWRLGLGDPRPIAAAHGRNVTSLIDEVLA
PFPPREANAAPPDLSNGIRIGVIGRPNVGKSTLVNRLLGEDRVVVYDEAGTTRDAIEIPFERRGKPYVLVDTAGVRRRKN
VSEAAEKFSIIKTLEAIKACNVAIMVLDARSGLVEQDLHLLDYVLSSGRALVLAVNKWDGLEQEAKDKMRAAIKRRLGFA
DYAEMHFISALHGTAVGDLYPSITRAFDSANSHWSTNRLTTILQDAVSEHQPPLIHGRRIKLRMAHQGGSNPPIIVVHGN
QTGSLPEAYKRYLTNTFRKVLKVRGTPLRFEFRSGKNPYDSNPDASDREKAKQRELGRTREARKNRR

Sequences:

>Translated_467_residues
MNPVIALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGNGVLGDKTYTVIDTGGISGNEEGLDAAMAEQSLLAID
EADIVLFMVDGRTGLNVADEAIANHLRVNQKKTWLVVNKTDGLEEHSAMAEFWRLGLGDPRPIAAAHGRNVTSLIDEVLA
PFPPREANAAPPDLSNGIRIGVIGRPNVGKSTLVNRLLGEDRVVVYDEAGTTRDAIEIPFERRGKPYVLVDTAGVRRRKN
VSEAAEKFSIIKTLEAIKACNVAIMVLDARSGLVEQDLHLLDYVLSSGRALVLAVNKWDGLEQEAKDKMRAAIKRRLGFA
DYAEMHFISALHGTAVGDLYPSITRAFDSANSHWSTNRLTTILQDAVSEHQPPLIHGRRIKLRMAHQGGSNPPIIVVHGN
QTGSLPEAYKRYLTNTFRKVLKVRGTPLRFEFRSGKNPYDSNPDASDREKAKQRELGRTREARKNRR
>Mature_467_residues
MNPVIALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGNGVLGDKTYTVIDTGGISGNEEGLDAAMAEQSLLAID
EADIVLFMVDGRTGLNVADEAIANHLRVNQKKTWLVVNKTDGLEEHSAMAEFWRLGLGDPRPIAAAHGRNVTSLIDEVLA
PFPPREANAAPPDLSNGIRIGVIGRPNVGKSTLVNRLLGEDRVVVYDEAGTTRDAIEIPFERRGKPYVLVDTAGVRRRKN
VSEAAEKFSIIKTLEAIKACNVAIMVLDARSGLVEQDLHLLDYVLSSGRALVLAVNKWDGLEQEAKDKMRAAIKRRLGFA
DYAEMHFISALHGTAVGDLYPSITRAFDSANSHWSTNRLTTILQDAVSEHQPPLIHGRRIKLRMAHQGGSNPPIIVVHGN
QTGSLPEAYKRYLTNTFRKVLKVRGTPLRFEFRSGKNPYDSNPDASDREKAKQRELGRTREARKNRR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=466, Percent_Identity=57.0815450643777, Blast_Score=544, Evalue=1e-156,
Organism=Escherichia coli, GI1788919, Length=175, Percent_Identity=30.8571428571429, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI2367268, Length=95, Percent_Identity=34.7368421052632, Blast_Score=62, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=225, Percent_Identity=28.4444444444444, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45550813, Length=147, Percent_Identity=38.0952380952381, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_CHRSD (Q1QTK4)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_574903.1
- ProteinModelPortal:   Q1QTK4
- SMR:   Q1QTK4
- STRING:   Q1QTK4
- GeneID:   4028660
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_2858
- NMPDR:   fig|290398.4.peg.2552
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- BioCyc:   CSAL290398:CSAL_2858-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 51558; Mature: 51558

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPVIALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGNGVLGDKTYTVIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCC
SGNEEGLDAAMAEQSLLAIDEADIVLFMVDGRTGLNVADEAIANHLRVNQKKTWLVVNKT
CCCCCCHHHHHHHHHHEEECCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEECC
DGLEEHSAMAEFWRLGLGDPRPIAAAHGRNVTSLIDEVLAPFPPREANAAPPDLSNGIRI
CCCHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
GVIGRPNVGKSTLVNRLLGEDRVVVYDEAGTTRDAIEIPFERRGKPYVLVDTAGVRRRKN
EEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCEEECCHHHCCCCEEEEECCCCHHHCC
VSEAAEKFSIIKTLEAIKACNVAIMVLDARSGLVEQDLHLLDYVLSSGRALVLAVNKWDG
HHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCC
LEQEAKDKMRAAIKRRLGFADYAEMHFISALHGTAVGDLYPSITRAFDSANSHWSTNRLT
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHH
TILQDAVSEHQPPLIHGRRIKLRMAHQGGSNPPIIVVHGNQTGSLPEAYKRYLTNTFRKV
HHHHHHHHHCCCCCEECCEEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
LKVRGTPLRFEFRSGKNPYDSNPDASDREKAKQRELGRTREARKNRR
HHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNPVIALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGNGVLGDKTYTVIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCC
SGNEEGLDAAMAEQSLLAIDEADIVLFMVDGRTGLNVADEAIANHLRVNQKKTWLVVNKT
CCCCCCHHHHHHHHHHEEECCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEECC
DGLEEHSAMAEFWRLGLGDPRPIAAAHGRNVTSLIDEVLAPFPPREANAAPPDLSNGIRI
CCCHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
GVIGRPNVGKSTLVNRLLGEDRVVVYDEAGTTRDAIEIPFERRGKPYVLVDTAGVRRRKN
EEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCEEECCHHHCCCCEEEEECCCCHHHCC
VSEAAEKFSIIKTLEAIKACNVAIMVLDARSGLVEQDLHLLDYVLSSGRALVLAVNKWDG
HHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCC
LEQEAKDKMRAAIKRRLGFADYAEMHFISALHGTAVGDLYPSITRAFDSANSHWSTNRLT
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHH
TILQDAVSEHQPPLIHGRRIKLRMAHQGGSNPPIIVVHGNQTGSLPEAYKRYLTNTFRKV
HHHHHHHHHCCCCCEECCEEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
LKVRGTPLRFEFRSGKNPYDSNPDASDREKAKQRELGRTREARKNRR
HHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA